CS270546B1 - Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu - Google Patents

Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu Download PDF

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CS270546B1
CS270546B1 CS889073A CS907388A CS270546B1 CS 270546 B1 CS270546 B1 CS 270546B1 CS 889073 A CS889073 A CS 889073A CS 907388 A CS907388 A CS 907388A CS 270546 B1 CS270546 B1 CS 270546B1
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Czechoslovakia
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propyl
mol
parts
formula
oxohexyl
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CS889073A
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Czech (cs)
English (en)
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CS907388A1 (en
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Alfonz Ing Csc Rybar
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Rybar Alfonz
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Priority to CS889073A priority Critical patent/CS270546B1/sk
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Publication of CS270546B1 publication Critical patent/CS270546B1/sk

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Abstract

Riešenia sa týká pripravy 3-uetyl-l5-oxohexyl)-7-n-propyl-3,7-dihydro-lH- ' -2,6-dionO vzorca I, ktorý sa použiva v medicine ako periférne vazodílatans a hemorsologlkum propeeitofylin. Postup spo-i čiva v to», že sa 3-«etyl-3,7-dihydro- í -lH-purin-2,6-dion vzorca II nechá rea-r š govaf s n-propylhalogenidois za prltoanos-: ti alkalického uhličitanu v prostředí vody alebo jej zeesi s alifatickým alko-j holom s počtoa uhlikov 1 až 3, pri teplo-' te 50 až 100 °C a po skončeni reakcie sa i přidá alkalický uhličitan alsbo hydroxid ' a 5-oxohexylhalogenií v aromatickom aleboi chlórovanom uhlovodicu a nechá sa rsago- : vat za přítomnosti katalyzátora aedzifázového přenosu pri taplote 30 až 120 OC.
CS889073A 1988-12-30 1988-12-30 Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu CS270546B1 (sk)

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Application Number Priority Date Filing Date Title
CS889073A CS270546B1 (sk) 1988-12-30 1988-12-30 Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS889073A CS270546B1 (sk) 1988-12-30 1988-12-30 Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu

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CS907388A1 CS907388A1 (en) 1989-11-14
CS270546B1 true CS270546B1 (sk) 1990-07-12

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CS889073A CS270546B1 (sk) 1988-12-30 1988-12-30 Sposob pripravy 3-metyl-l-(5-oxohexyl)- -7-n-propyl-3,7-dihydro-lH-purin-2,6- -dionu

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CS907388A1 (en) 1989-11-14

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