CU21532A3 - Procedure for the production of bicyclic compounds - Google Patents

Procedure for the production of bicyclic compounds

Info

Publication number
CU21532A3
CU21532A3 CU8335899A CU35899A CU21532A3 CU 21532 A3 CU21532 A3 CU 21532A3 CU 8335899 A CU8335899 A CU 8335899A CU 35899 A CU35899 A CU 35899A CU 21532 A3 CU21532 A3 CU 21532A3
Authority
CU
Cuba
Prior art keywords
procedure
production
bicyclic compounds
bicyclic
compounds
Prior art date
Application number
CU8335899A
Other languages
English (en)
Inventor
Michael R Attwood
Cedric H Hassall
Robert W Lambert
Geoffrey Lawton
Sally Redshaw
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CU21532A3 publication Critical patent/CU21532A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/409—Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
    • C07F9/650947—Six-membered rings having the nitrogen atoms in the positions 1 and 2 condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CU8335899A 1982-05-12 1983-05-09 Procedure for the production of bicyclic compounds CU21532A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8213850 1982-05-12
GB08305505A GB2128984B (en) 1982-05-12 1983-02-28 Diaza-bicyclic compounds

Publications (1)

Publication Number Publication Date
CU21532A3 true CU21532A3 (en) 1987-06-09

Family

ID=26282820

Family Applications (1)

Application Number Title Priority Date Filing Date
CU8335899A CU21532A3 (en) 1982-05-12 1983-05-09 Procedure for the production of bicyclic compounds

Country Status (32)

Country Link
US (3) US4512924A (fr)
EP (1) EP0094095B1 (fr)
KR (1) KR890002106B1 (fr)
AR (1) AR240940A1 (fr)
AU (1) AU567873B2 (fr)
BG (1) BG61123B2 (fr)
CA (1) CA1234568A (fr)
CS (2) CS249128B2 (fr)
CU (1) CU21532A3 (fr)
DE (2) DE3381884D1 (fr)
DK (1) DK160612C (fr)
DO (1) DOP1983004163A (fr)
DZ (1) DZ540A1 (fr)
ES (6) ES522291A0 (fr)
FI (1) FI77244C (fr)
FR (1) FR2531956B1 (fr)
GB (1) GB2128984B (fr)
GR (1) GR77462B (fr)
HK (1) HK91692A (fr)
HU (3) HU198935B (fr)
IE (1) IE56480B1 (fr)
IL (1) IL68620A (fr)
IT (1) IT1212738B (fr)
LU (2) LU84803A1 (fr)
MC (1) MC1515A1 (fr)
MY (1) MY102889A (fr)
NL (2) NL8301640A (fr)
NO (1) NO160368C (fr)
PT (1) PT76681B (fr)
SE (1) SE461792B (fr)
SG (1) SG81192G (fr)
ZW (1) ZW9883A1 (fr)

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CN107674071B (zh) 2012-05-11 2021-12-31 同步制药公司 作为隐花色素调节剂的含有咔唑的磺酰胺类
ES2786506T3 (es) 2012-08-01 2020-10-13 Zahra Tavakoli Composiciones congeladas fluidas que comprenden un agente terapéutico
US20160024098A1 (en) 2013-03-15 2016-01-28 President And Fellows Of Harvard College Hybrid necroptosis inhibitors
BR112015024234B1 (pt) 2013-03-21 2022-11-16 Eupraxia Pharmaceuticals USA LLC Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
DK3206672T3 (en) 2015-10-27 2018-06-18 Eupraxia Pharmaceuticals Inc Formulations for sustained release of local anesthetics

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IL60617A0 (en) * 1979-07-23 1980-09-16 Sparamedica Ag Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them
DE3062972D1 (en) * 1979-09-19 1983-06-09 Hoffmann La Roche Pyridazopyridazine derivatives, processes for their preparation and pharmaceutical compositions containing these pyridazopyridazine derivatives
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IE831084L (en) 1983-11-12
NO160368C (no) 1989-04-12
SE8302716L (sv) 1983-11-13
FI831661L (fi) 1983-11-13
DK194783A (da) 1983-11-13
IE56480B1 (en) 1991-08-14
GB2128984A (en) 1984-05-10
IL68620A (en) 1987-11-30
HU198935B (en) 1989-12-28
NL930055I2 (nl) 1993-10-01
ES8607970A1 (es) 1986-06-16
MY102889A (en) 1993-03-31
IT1212738B (it) 1989-11-30
AU1436483A (en) 1983-11-17
DE3381884D1 (de) 1990-10-25
PT76681B (en) 1986-05-20
CS249128B2 (en) 1987-03-12
AR240940A1 (es) 1991-03-27
US4512924A (en) 1985-04-23
DZ540A1 (fr) 2004-09-13
HU199842B (en) 1990-03-28
GB8305505D0 (en) 1983-03-30
FR2531956B1 (fr) 1987-02-20
ES8407049A1 (es) 1984-08-16
GR77462B (fr) 1984-09-24
ES528628A0 (es) 1987-07-16
ES528630A0 (es) 1986-06-16
HU195965B (en) 1988-08-29
FI831661A0 (fi) 1983-05-12
CS402191A3 (en) 1992-10-14
BG61123B2 (bg) 1996-11-29
NL8301640A (nl) 1983-12-01
LU88299I2 (fr) 1994-09-09
SE461792B (sv) 1990-03-26
FI77244C (fi) 1989-02-10
NO160368B (no) 1989-01-02
CA1234568A (fr) 1988-03-29
ES528627A0 (es) 1985-11-16
US4772701A (en) 1988-09-20
ES528625A0 (es) 1985-05-16
ES8706672A1 (es) 1987-07-16
ES8505173A1 (es) 1985-05-16
IT8321000A0 (it) 1983-05-09
IL68620A0 (en) 1983-09-30
DK160612B (da) 1991-04-02
DK160612C (da) 1991-09-23
NL930055I1 (nl) 1993-09-01
AU567873B2 (en) 1987-12-10
SG81192G (en) 1993-01-29
HK91692A (en) 1992-11-27
ES8800170A1 (es) 1987-11-01
KR890002106B1 (ko) 1989-06-19
US4658024A (en) 1987-04-14
PT76681A (en) 1983-06-01
GB2128984B (en) 1985-05-22
EP0094095A3 (en) 1984-11-21
NO831675L (no) 1983-11-14
ES8601994A1 (es) 1985-11-16
EP0094095A2 (fr) 1983-11-16
EP0094095B1 (fr) 1990-09-19
ES522291A0 (es) 1984-08-16
FR2531956A1 (fr) 1984-02-24
FI77244B (fi) 1988-10-31
DK194783D0 (da) 1983-05-02
LU84803A1 (fr) 1985-03-21
MC1515A1 (fr) 1984-02-10
AR240940A2 (es) 1991-03-27
DE3317290A1 (de) 1983-11-17
SE8302716D0 (sv) 1983-05-11
KR840004754A (ko) 1984-10-24
ZW9883A1 (en) 1984-11-21
ES554935A0 (es) 1987-11-01
DOP1983004163A (es) 1988-09-20

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