CU24495B1 - Compuestos que expanden las células hematopoyéticas y método ex vivo para expandir las células hematopoyéticas - Google Patents

Compuestos que expanden las células hematopoyéticas y método ex vivo para expandir las células hematopoyéticas

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Publication number
CU24495B1
CU24495B1 CU2011000096A CU20110096A CU24495B1 CU 24495 B1 CU24495 B1 CU 24495B1 CU 2011000096 A CU2011000096 A CU 2011000096A CU 20110096 A CU20110096 A CU 20110096A CU 24495 B1 CU24495 B1 CU 24495B1
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Prior art keywords
hematopoietic cells
expand hematopoietic
compounds
vivo method
relates
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CU2011000096A
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English (en)
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CU20110096A7 (es
Inventor
Anthony Boitano
Michael Cooke
Shifeng Pan
Peter G Schultz
John TELLEW
Yongqin Wan
Xing Wang
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Novartis Ag
Scripps Research Inst
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Application filed by Novartis Ag, Scripps Research Inst filed Critical Novartis Ag
Publication of CU20110096A7 publication Critical patent/CU20110096A7/es
Publication of CU24495B1 publication Critical patent/CU24495B1/es

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Abstract

La presente invención se refiere a compuestos para expandir el número de células CD34+ para trasplante. La invención se refiere además a una población celular que comprende células madre hematopoyéticas (HSCs) expandidas, y a su uso en trasplante autólogo o alogénico para el tratamiento de los pacientes con enfermedades de inmunodeficiencia y autoinmunes heredadas y diversos trastornos hematopoyéticos, con el fin de reconstituir los linajes de células hematopoyéticas y las defensas del sistema inmunitario. La invención también se refiere a un método ex vivo para expandir células madre hematopoyéticas.</p>
CU2011000096A 2008-10-30 2009-10-29 Compuestos que expanden las células hematopoyéticas y método ex vivo para expandir las células hematopoyéticas CU24495B1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10982108P 2008-10-30 2008-10-30
US24276509P 2009-09-15 2009-09-15
PCT/US2009/062646 WO2010059401A2 (en) 2008-10-30 2009-10-29 Compounds that expand hematopoietic stem cells

Publications (2)

Publication Number Publication Date
CU20110096A7 CU20110096A7 (es) 2012-01-31
CU24495B1 true CU24495B1 (es) 2021-01-12

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CU2011000096A CU24495B1 (es) 2008-10-30 2009-10-29 Compuestos que expanden las células hematopoyéticas y método ex vivo para expandir las células hematopoyéticas

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US (4) US8927281B2 (es)
EP (2) EP2350078B1 (es)
JP (1) JP5390626B2 (es)
KR (1) KR101434719B1 (es)
CN (1) CN102203096B (es)
AR (1) AR074063A1 (es)
AU (1) AU2009317898B2 (es)
BR (1) BRPI0921799B8 (es)
CA (3) CA2740589C (es)
CL (2) CL2009002010A1 (es)
CO (1) CO6410309A2 (es)
CR (1) CR20110192A (es)
CU (1) CU24495B1 (es)
CY (1) CY1121857T1 (es)
DK (1) DK2350078T3 (es)
DO (1) DOP2011000114A (es)
EA (1) EA019872B1 (es)
EC (1) ECSP11011090A (es)
ES (2) ES2948567T3 (es)
GE (1) GEP20146053B (es)
HN (1) HN2011001195A (es)
HR (1) HRP20191238T1 (es)
HU (1) HUE044802T2 (es)
IL (1) IL212368A (es)
JO (1) JO3593B1 (es)
LT (1) LT2350078T (es)
MA (1) MA32828B1 (es)
MX (1) MX347834B (es)
MY (1) MY155137A (es)
NI (1) NI201100083A (es)
NZ (1) NZ592435A (es)
PE (1) PE20100362A1 (es)
PL (1) PL2350078T3 (es)
PT (1) PT2350078T (es)
RS (1) RS59027B1 (es)
SI (1) SI2350078T1 (es)
SM (1) SMP201100024B (es)
SV (1) SV2011003888A (es)
TN (1) TN2011000174A1 (es)
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WO (1) WO2010059401A2 (es)

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