CY2247B1 - Indole derivative - Google Patents

Indole derivative

Info

Publication number
CY2247B1
CY2247B1 CY0100039A CY0100039A CY2247B1 CY 2247 B1 CY2247 B1 CY 2247B1 CY 0100039 A CY0100039 A CY 0100039A CY 0100039 A CY0100039 A CY 0100039A CY 2247 B1 CY2247 B1 CY 2247B1
Authority
CY
Cyprus
Prior art keywords
lower alkoxy
alkoxy
alkoxycarbonyl
indole derivative
carboxy
Prior art date
Application number
CY0100039A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Harada
Yoshimi Hirokawa
Naoyuki Yoshida
Hitoshi Kawashima
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of CY2247B1 publication Critical patent/CY2247B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CY0100039A 1994-11-29 2001-11-20 Indole derivative CY2247B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP06321402 1994-11-29

Publications (1)

Publication Number Publication Date
CY2247B1 true CY2247B1 (en) 2003-07-04

Family

ID=18132155

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0100039A CY2247B1 (en) 1994-11-29 2001-11-20 Indole derivative

Country Status (28)

Country Link
US (1) US5817689A (da)
EP (1) EP0801059B1 (da)
JP (1) JP3100165B2 (da)
KR (1) KR100388747B1 (da)
CN (1) CN1070477C (da)
AT (1) ATE202559T1 (da)
AU (1) AU688165B2 (da)
BR (1) BR9509827A (da)
CA (1) CA2206307A1 (da)
CY (1) CY2247B1 (da)
CZ (1) CZ290871B6 (da)
DE (1) DE69521529T2 (da)
DK (1) DK0801059T3 (da)
ES (1) ES2159648T3 (da)
FI (1) FI972275A7 (da)
GR (1) GR3036148T3 (da)
HU (1) HUT77308A (da)
IL (1) IL116178A (da)
NO (1) NO309648B1 (da)
NZ (1) NZ295749A (da)
PL (1) PL181963B1 (da)
PT (1) PT801059E (da)
RO (1) RO118426B1 (da)
RU (1) RU2137759C1 (da)
SK (1) SK281865B6 (da)
TW (1) TW349091B (da)
WO (1) WO1996016938A1 (da)
ZA (1) ZA9510130B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010580A1 (es) * 1999-09-03 2001-05-25 Takeda Chemical Industries Ltd Composicion farmaceutica para tratar la diabetes
US6458824B1 (en) * 1999-11-30 2002-10-01 Dainippon Pharmaceutical Co., Ltd. Solid preparation
NZ519086A (en) * 1999-11-30 2003-11-28 Dainippon Pharmaceutical Co Solid preparation
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
AU2003225277A1 (en) * 2002-05-02 2003-11-17 Robert Harris Lipid removal from the body
KR20050010512A (ko) * 2002-06-12 2005-01-27 스미또모 세이야꾸 가부시키가이샤 인돌, 인다졸 및 벤즈아졸류
RS20050532A (sr) 2003-01-14 2007-12-31 Arena Pharmaceuticals Inc., Derivati 1,2,3-trisupstituisanog arila i heteroarila kao modulatori metabolizma za profilaksu i tretman poremećaja povezanih sa njim, kao što su dijebetes i hiperglikemija
SI1599468T1 (sl) * 2003-01-14 2008-02-29 Arena Pharm Inc 1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2004089936A1 (ja) * 2003-04-10 2004-10-21 Dainippon Pharmaceutical Co., Ltd. ヘテロアリールスルホン酸アニリド誘導体及びそれを含有する医薬組成物
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
EP2428516A1 (en) * 2003-11-19 2012-03-14 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
CN1922174A (zh) 2004-02-20 2007-02-28 贝林格尔·英格海姆国际有限公司 病毒聚合酶抑制剂
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
CA2618682C (en) * 2005-08-12 2011-06-21 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
CN103221410B (zh) 2010-09-22 2017-09-15 艾尼纳制药公司 Gpr119受体调节剂和对与其相关的障碍的治疗
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
WO2015199097A1 (ja) * 2014-06-24 2015-12-30 花王株式会社 Ｕｃｐ－１発現促進剤
US10758519B2 (en) 2014-06-24 2020-09-01 Kao Corporation UCP-1 expression promoter
JP6660668B2 (ja) * 2014-06-24 2020-03-11 花王株式会社 Ｕｃｐ−１発現促進剤
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB861428A (en) * 1958-07-14 1961-02-22 Searle & Co Improvements in or relating to indole derivatives
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
US4338333A (en) * 1979-06-16 1982-07-06 Beecham Group Limited Ethanamine derivatives their preparation and use in pharmaceutical compositions
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
JPH06345731A (ja) * 1992-04-28 1994-12-20 Dainippon Pharmaceut Co Ltd ２−〔２−（インドール−３−イル）エチルアミノ〕−１−フェニルエタノール誘導体
JPH0634531A (ja) * 1992-07-14 1994-02-08 Yokogawa Electric Corp 赤外線水分計

Also Published As

Publication number Publication date
AU688165B2 (en) 1998-03-05
CN1070477C (zh) 2001-09-05
PT801059E (pt) 2001-10-30
ES2159648T3 (es) 2001-10-16
SK281865B6 (sk) 2001-08-06
IL116178A0 (en) 1996-01-31
DE69521529D1 (de) 2001-08-02
AU3936695A (en) 1996-06-19
CN1174549A (zh) 1998-02-25
TW349091B (en) 1999-01-01
FI972275A0 (fi) 1997-05-29
MX9703858A (es) 1997-09-30
HUT77308A (hu) 1998-03-30
NO309648B1 (no) 2001-03-05
CZ165597A3 (en) 1997-11-12
SK65697A3 (en) 1998-01-14
EP0801059A4 (en) 1998-01-21
KR100388747B1 (ko) 2004-03-30
DE69521529T2 (de) 2001-10-11
FI972275L (fi) 1997-05-29
US5817689A (en) 1998-10-06
RU2137759C1 (ru) 1999-09-20
CA2206307A1 (en) 1996-06-06
NZ295749A (en) 1998-05-27
RO118426B1 (ro) 2003-05-30
CZ290871B6 (cs) 2002-11-13
NO972427D0 (no) 1997-05-28
PL320461A1 (en) 1997-09-29
IL116178A (en) 2000-07-26
NO972427L (no) 1997-07-28
FI972275A7 (fi) 1997-05-29
WO1996016938A1 (en) 1996-06-06
ATE202559T1 (de) 2001-07-15
BR9509827A (pt) 1997-09-30
JP3100165B2 (ja) 2000-10-16
EP0801059B1 (en) 2001-06-27
EP0801059A1 (en) 1997-10-15
HK1003886A1 (en) 1998-11-13
DK0801059T3 (da) 2001-09-24
PL181963B1 (pl) 2001-10-31
ZA9510130B (en) 1996-06-11
GR3036148T3 (en) 2001-09-28

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