CY2247B1 - Indole derivative - Google Patents

Indole derivative

Info

Publication number
CY2247B1
CY2247B1 CY0100039A CY0100039A CY2247B1 CY 2247 B1 CY2247 B1 CY 2247B1 CY 0100039 A CY0100039 A CY 0100039A CY 0100039 A CY0100039 A CY 0100039A CY 2247 B1 CY2247 B1 CY 2247B1
Authority
CY
Cyprus
Prior art keywords
lower alkoxy
alkoxy
alkoxycarbonyl
indole derivative
carboxy
Prior art date
Application number
CY0100039A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Harada
Yoshimi Hirokawa
Naoyuki Yoshida
Hitoshi Kawashima
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of CY2247B1 publication Critical patent/CY2247B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CY0100039A 1994-11-29 2001-11-20 Indole derivative CY2247B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP06321402 1994-11-29

Publications (1)

Publication Number Publication Date
CY2247B1 true CY2247B1 (en) 2003-07-04

Family

ID=18132155

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0100039A CY2247B1 (en) 1994-11-29 2001-11-20 Indole derivative

Country Status (28)

Country Link
US (1) US5817689A (pt)
EP (1) EP0801059B1 (pt)
JP (1) JP3100165B2 (pt)
KR (1) KR100388747B1 (pt)
CN (1) CN1070477C (pt)
AT (1) ATE202559T1 (pt)
AU (1) AU688165B2 (pt)
BR (1) BR9509827A (pt)
CA (1) CA2206307A1 (pt)
CY (1) CY2247B1 (pt)
CZ (1) CZ290871B6 (pt)
DE (1) DE69521529T2 (pt)
DK (1) DK0801059T3 (pt)
ES (1) ES2159648T3 (pt)
FI (1) FI972275A0 (pt)
GR (1) GR3036148T3 (pt)
HU (1) HUT77308A (pt)
IL (1) IL116178A (pt)
NO (1) NO309648B1 (pt)
NZ (1) NZ295749A (pt)
PL (1) PL181963B1 (pt)
PT (1) PT801059E (pt)
RO (1) RO118426B1 (pt)
RU (1) RU2137759C1 (pt)
SK (1) SK281865B6 (pt)
TW (1) TW349091B (pt)
WO (1) WO1996016938A1 (pt)
ZA (1) ZA9510130B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010580A1 (es) * 1999-09-03 2001-05-25 Takeda Chemical Industries Ltd Composicion farmaceutica para tratar la diabetes
US6458824B1 (en) * 1999-11-30 2002-10-01 Dainippon Pharmaceutical Co., Ltd. Solid preparation
HUP0203865A3 (en) * 1999-11-30 2004-05-28 Dainippon Pharmaceutical Co Solid pharmaceutical composition containing crystal of [3-[(2r)-[[(2r)-(3-clorophenyl)-2-hydroxy-ethyl]amino]propyl]-1h-indol-7-yloxy]-acetic acid
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
US20040018959A1 (en) * 2002-05-02 2004-01-29 Randall S. Hickle System and methods of lipid removal from the body
AU2003242245A1 (en) * 2002-06-12 2003-12-31 Sumitomo Pharmaceuticals Co., Ltd. Indole, indazole, and benzazole derivative
EP1927594A1 (en) * 2003-01-14 2008-06-04 Arena Pharmaceuticals, Inc. 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
MXPA05007485A (es) 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
US7098231B2 (en) * 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2004089936A1 (ja) * 2003-04-10 2004-10-21 Dainippon Pharmaceutical Co., Ltd. ヘテロアリールスルホン酸アニリド誘導体及びそれを含有する医薬組成物
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
CN1882327A (zh) * 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
CN102911161A (zh) 2004-02-20 2013-02-06 贝林格尔.英格海姆国际有限公司 病毒聚合酶抑制剂
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
US8076365B2 (en) * 2005-08-12 2011-12-13 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
EP3323818A1 (en) 2010-09-22 2018-05-23 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
JP6660668B2 (ja) * 2014-06-24 2020-03-11 花王株式会社 Ｕｃｐ−１発現促進剤
WO2015199097A1 (ja) * 2014-06-24 2015-12-30 花王株式会社 Ｕｃｐ－１発現促進剤
US10758519B2 (en) 2014-06-24 2020-09-01 Kao Corporation UCP-1 expression promoter
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
BR112017027656B1 (pt) 2015-06-22 2023-12-05 Arena Pharmaceuticals, Inc. Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB861428A (en) * 1958-07-14 1961-02-22 Searle & Co Improvements in or relating to indole derivatives
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
US4338333A (en) * 1979-06-16 1982-07-06 Beecham Group Limited Ethanamine derivatives their preparation and use in pharmaceutical compositions
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
JPH06345731A (ja) * 1992-04-28 1994-12-20 Dainippon Pharmaceut Co Ltd ２−〔２−（インドール−３−イル）エチルアミノ〕−１−フェニルエタノール誘導体
JPH0634531A (ja) * 1992-07-14 1994-02-08 Yokogawa Electric Corp 赤外線水分計

Also Published As

Publication number Publication date
NO972427D0 (no) 1997-05-28
PL320461A1 (en) 1997-09-29
TW349091B (en) 1999-01-01
CA2206307A1 (en) 1996-06-06
RO118426B1 (ro) 2003-05-30
DE69521529T2 (de) 2001-10-11
CN1174549A (zh) 1998-02-25
PT801059E (pt) 2001-10-30
SK281865B6 (sk) 2001-08-06
IL116178A (en) 2000-07-26
HUT77308A (hu) 1998-03-30
CN1070477C (zh) 2001-09-05
CZ165597A3 (en) 1997-11-12
FI972275L (fi) 1997-05-29
NO309648B1 (no) 2001-03-05
SK65697A3 (en) 1998-01-14
CZ290871B6 (cs) 2002-11-13
US5817689A (en) 1998-10-06
BR9509827A (pt) 1997-09-30
FI972275A7 (fi) 1997-05-29
EP0801059A1 (en) 1997-10-15
DK0801059T3 (da) 2001-09-24
HK1003886A1 (en) 1998-11-13
EP0801059B1 (en) 2001-06-27
ZA9510130B (en) 1996-06-11
EP0801059A4 (en) 1998-01-21
RU2137759C1 (ru) 1999-09-20
WO1996016938A1 (en) 1996-06-06
KR100388747B1 (ko) 2004-03-30
NO972427L (no) 1997-07-28
AU688165B2 (en) 1998-03-05
GR3036148T3 (en) 2001-09-28
DE69521529D1 (de) 2001-08-02
FI972275A0 (fi) 1997-05-29
NZ295749A (en) 1998-05-27
ATE202559T1 (de) 2001-07-15
JP3100165B2 (ja) 2000-10-16
ES2159648T3 (es) 2001-10-16
PL181963B1 (pl) 2001-10-31
IL116178A0 (en) 1996-01-31
AU3936695A (en) 1996-06-19
MX9703858A (es) 1997-09-30

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