CY2512B1 - Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application - Google Patents

Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application

Info

Publication number: CY2512B1
Authority: CY; Cyprus
Prior art keywords: valaciclovir; genital herpes; pharmaceutically acceptable; acceptable salt; suppression
Prior art date: 1996-01-19

Application number

CY0500026A

Other languages

English (en)

Inventor

John Delehanty

Margaret L Smiley

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-19

Filing date

2005-04-18

Publication date

2005-12-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24399659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2512(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-04-18 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2005-12-23 Publication of CY2512B1 publication Critical patent/CY2512B1/xx

Links

HDOVUKNUBWVHOX-QMMMGPOBSA-N Valacyclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCOC(=O)[C@@H](N)C(C)C)C=N2 HDOVUKNUBWVHOX-QMMMGPOBSA-N 0.000 title abstract 6
229940093257 valacyclovir Drugs 0.000 title abstract 6
208000001688 Herpes Genitalis Diseases 0.000 title abstract 5
201000004946 genital herpes Diseases 0.000 title abstract 5
239000003814 drug Substances 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 4
230000001629 suppression Effects 0.000 abstract 3
MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 2
239000002552 dosage form Substances 0.000 abstract 2
230000000306 recurrent effect Effects 0.000 abstract 2
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
229960004150 aciclovir Drugs 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1
-1 valine ester Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

CY0500026A 1996-01-19 2005-04-18 Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application CY2512B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59944896A	1996-01-19	1996-01-19

Publications (1)

Publication Number	Publication Date
CY2512B1 true CY2512B1 (en)	2005-12-23

Family

ID=24399659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY0500026A CY2512B1 (en)	1996-01-19	2005-04-18	Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application

Country Status (12)

Country	Link
EP (1)	EP0874631B1 (da)
JP (1)	JP4097698B2 (da)
AT (1)	ATE254463T1 (da)
AU (1)	AU722304B2 (da)
CA (1)	CA2243237C (da)
CY (1)	CY2512B1 (da)
DE (1)	DE69726255T2 (da)
DK (1)	DK0874631T3 (da)
ES (1)	ES2210490T3 (da)
PT (1)	PT874631E (da)
WO (1)	WO1997025989A1 (da)
ZA (1)	ZA97400B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0010446D0 (en) *	2000-04-28	2000-06-14	Glaxo Wellcome Kk	Pharmaceutical formulation
ITMI20010009A1 (it) *	2001-01-03	2002-07-03	Menarini Ricerche Spa	Composizioni farmaceutica contenente brivudina per la singola somministrazione giornaliera
CN1551880A (zh) *	2001-09-07	2004-12-01	��ҩ��ҵ��޹�˾	阿昔洛韦缬氨酸酯盐酸盐的晶型
IL161969A0 (en) *	2001-11-14	2005-11-20	Teva Pharma	Synthesis and purification of valacyclovir
US7229644B2 (en) *	2002-05-23	2007-06-12	Cephalon, Inc.	Pharmaceutical formulations of modafinil
EP1517678A2 (en) *	2002-06-24	2005-03-30	Ranbaxy Laboratories Limited	Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20040116532A1 (en) *	2002-09-13	2004-06-17	Craig Heacock	Pharmaceutical formulations of modafinil
WO2004106338A1 (en) *	2003-05-30	2004-12-09	Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S.	Novel crystalline forms of valacyclovir hydrochloride
CN1331471C (zh) *	2003-09-22	2007-08-15	陈云芳	盐酸万乃洛韦软胶囊组合物
WO2007090595A1 (en) *	2006-02-06	2007-08-16	Fidia Pharmaceutici S.P.A.	Solid formulations of valacyclovir hydrochloride
GB0605344D0 (en) *	2006-03-17	2006-04-26	Pliva Istrazivanje I Razvoj D	Pharmaceutically acceptable salts and polymorphic forms
JP4669804B2 (ja) *	2006-03-28	2011-04-13	株式会社オーディオテクニカ	コンデンサマイクロホン
CN1903854B (zh) *	2006-08-09	2012-05-23	丽珠医药集团股份有限公司	一种合成盐酸伐昔洛韦的方法
JPWO2009031576A1 (ja) *	2007-09-03	2010-12-16	味の素株式会社	バラシクロビル塩酸塩結晶の製造方法
CN104188928B (zh) *	2014-09-17	2017-07-28	山东新时代药业有限公司	一种盐酸伐昔洛韦片剂及其制备方法
WO2020049536A1 (en) *	2018-09-07	2020-03-12	Jubilant Generics Limited	Pharmaceutical compositions of valacyclovir or its pharmaceutically acceptable salts thereof
CN109651371B (zh) *	2018-12-31	2021-02-23	辰欣药业股份有限公司	一种盐酸伐昔洛韦的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AP160A (en) *	1987-08-15	1991-11-18	The Wellcome Foundation Ltd	Therapeutic acyclic nucleosides.
GB9320316D0 (en) *	1993-10-01	1993-11-17	Smithkline Beecham Plc	Pharmaceuticals
GB9501178D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Guanine derivative
GB9501127D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Tablet

1997
- 1997-01-17 CA CA002243237A patent/CA2243237C/en not_active Expired - Fee Related
- 1997-01-17 JP JP52569197A patent/JP4097698B2/ja not_active Expired - Fee Related
- 1997-01-17 PT PT97901052T patent/PT874631E/pt unknown
- 1997-01-17 AT AT97901052T patent/ATE254463T1/de not_active IP Right Cessation
- 1997-01-17 WO PCT/EP1997/000192 patent/WO1997025989A1/en not_active Ceased
- 1997-01-17 EP EP97901052A patent/EP0874631B1/en not_active Revoked
- 1997-01-17 DE DE69726255T patent/DE69726255T2/de not_active Expired - Lifetime
- 1997-01-17 ZA ZA9700400A patent/ZA97400B/xx unknown
- 1997-01-17 ES ES97901052T patent/ES2210490T3/es not_active Expired - Lifetime
- 1997-01-17 DK DK97901052T patent/DK0874631T3/da active
- 1997-01-17 AU AU14434/97A patent/AU722304B2/en not_active Ceased
2005
- 2005-04-18 CY CY0500026A patent/CY2512B1/xx unknown

Also Published As

Publication number	Publication date
CA2243237C (en)	2008-09-02
ZA97400B (en)	1997-11-13
DK0874631T3 (da)	2004-03-22
DE69726255T2 (de)	2004-08-26
JP2000503310A (ja)	2000-03-21
ES2210490T3 (es)	2004-07-01
CA2243237A1 (en)	1997-07-24
EP0874631A1 (en)	1998-11-04
WO1997025989A1 (en)	1997-07-24
EP0874631B1 (en)	2003-11-19
ATE254463T1 (de)	2003-12-15
AU1443497A (en)	1997-08-11
PT874631E (pt)	2004-04-30
DE69726255D1 (de)	2003-12-24
AU722304B2 (en)	2000-07-27
JP4097698B2 (ja)	2008-06-11

Publication	Publication Date	Title
ZA97400B (en)	1997-11-13	Valaciclovir.
JP3924321B2 (ja)	2007-06-06	疼痛軽減医薬組成物及び疼痛軽減方法
NZ508526A (en)	2004-12-24	Opioid formulations for treating pain
UA40589C2 (uk)	2001-08-15	Спосіб лікування людини, що страждає від вірусної інфекції, фармацевтична композиція, комбінація речовин для отримання ліків та фармацевтична комбінація
MY125662A (en)	2006-08-30	Pharmaceutical formulations containing darifenacin
RU2000111506A (ru)	2002-05-10	Таблетки с пролонгированным выделением для лечения болезни паркинсона
WO2005065069A3 (en)	2005-09-22	Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
CA2098738A1 (en)	1993-05-28	Controlled Release Oxycodone Compositions
ATE424810T1 (de)	2009-03-15	Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
US4438138A (en)	1984-03-20	Reduction of cholesterol with meta-chloro α-t-butylaminopropiophenone
CA2795038C (en)	2016-05-17	Opioid receptor antagonist (naltrexone) for use in treating herpes zoster disease
CA2180178A1 (en)	1995-07-06	Use of 2,3-diaryl-1-benzopyran derivatives for the manufacture of a medicament in the treatment and prevention of bone loss and osteoporosis
PT1027053E (pt)	2004-09-30	Metodo de prevencao de nefrotoxicidade provocada por ciclosporinas e tacrolimus
MY124465A (en)	2006-06-30	Reduction of infarct volume using citicoline
JPH08283148A (ja)	1996-10-29	うつ性症状改善剤
NO974486L (no)	1997-09-29	Lavdoserte "Ridogrel"-formuleringer samt anvendelse derav ved behandling av tarmbetennelse
WO1992015315A1 (en)	1992-09-17	Method for the treatment of herpes
HU211305A9 (en)	1995-11-28	Novel method for treatment of parkinson's disease
RU99112967A (ru)	2001-04-27	Способ лечения и профилактики дизентерии свиней
JP4344532B2 (ja)	2009-10-14	鼻炎用組成物
EP3530273B1 (en)	2024-08-14	A3 adenosine receptor ligands for use in the treatment of a sexual dysfunction
AR020167A1 (es)	2002-04-10	Metodo para la prevencion del inicio del asma
JP2004026810A (ja)	2004-01-29	鼻炎用組成物
IE20010413A1 (en)	2003-04-16	Once-a-day pharmaceutical composition containing Brivudine
TH18176A (th)	1996-04-19	อิมัลชันชนิดน้ำมัน-ใน-น้ำ