DD206377A5 - Verfahren zur herstellung von (thienyl-2)- und (thienyl-3)-2-ethylamin-derivaten - Google Patents

Verfahren zur herstellung von (thienyl-2)- und (thienyl-3)-2-ethylamin-derivaten Download PDF

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Publication number
DD206377A5
DD206377A5 DD82241200A DD24120082A DD206377A5 DD 206377 A5 DD206377 A5 DD 206377A5 DD 82241200 A DD82241200 A DD 82241200A DD 24120082 A DD24120082 A DD 24120082A DD 206377 A5 DD206377 A5 DD 206377A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
ppm
thienyl
item
compound
Prior art date
Application number
DD82241200A
Other languages
German (de)
English (en)
Inventor
Isaac Chekroun
Alain Heymes
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DD206377A5 publication Critical patent/DD206377A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5004—Acyclic saturated phosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Saccharide Compounds (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
DD82241200A 1981-06-30 1982-06-29 Verfahren zur herstellung von (thienyl-2)- und (thienyl-3)-2-ethylamin-derivaten DD206377A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113062A FR2508453A1 (fr) 1981-06-30 1981-06-30 Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus

Publications (1)

Publication Number Publication Date
DD206377A5 true DD206377A5 (de) 1984-01-25

Family

ID=9260129

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82241200A DD206377A5 (de) 1981-06-30 1982-06-29 Verfahren zur herstellung von (thienyl-2)- und (thienyl-3)-2-ethylamin-derivaten

Country Status (24)

Country Link
US (1) US4482718A (cs)
EP (1) EP0068978B1 (cs)
JP (1) JPS5810574A (cs)
KR (1) KR840000536A (cs)
AT (1) ATE21897T1 (cs)
AU (1) AU566802B2 (cs)
CA (1) CA1205810A (cs)
CS (1) CS248028B2 (cs)
DD (1) DD206377A5 (cs)
DE (1) DE3273015D1 (cs)
DK (1) DK286682A (cs)
ES (1) ES514221A0 (cs)
FI (1) FI822315A7 (cs)
FR (1) FR2508453A1 (cs)
GR (1) GR76496B (cs)
HU (1) HU194860B (cs)
IE (1) IE53228B1 (cs)
IL (1) IL65980A (cs)
NO (1) NO155136C (cs)
NZ (1) NZ200852A (cs)
PT (1) PT75152B (cs)
SU (1) SU1148563A3 (cs)
YU (1) YU143382A (cs)
ZA (1) ZA824624B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508454A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines et produits ainsi obtenus
CA1292747C (en) * 1983-11-21 1991-12-03 John Robert Carson Aralykyl (arylethynyl) aralkyl amines and their use as vasodilators and antihypertensives
ES8604853A1 (es) * 1983-11-21 1986-03-01 Mcneilab Inc Un metodo para la preparacion de un derivado de acetileno.
FR2622191B1 (fr) * 1987-10-22 1991-06-21 Sanofi Sa Procede de preparation de la n-(chloro-2 benzyl)-2 ethylamine et produits intermediaires dans cette preparation
JPH0283380A (ja) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk 新規ジアミン誘導体、抗不整脈剤及びその製法
US4900539A (en) * 1988-12-22 1990-02-13 The United States Of America As Represented By The United States Department Of Energy Radiohalogenated thienylethylamine derivatives for evaluating local cerebral blood flow
WO1993003025A1 (en) * 1991-08-09 1993-02-18 Yoshitomi Pharmaceutical Industries, Ltd. Thiophene compound
JP5986635B2 (ja) * 2011-08-17 2016-09-06 シャンドン リュイェ ファーマシューティカル カンパニー リミテッドＳｈａｎ Ｄｏｎｇ Ｌｕｙｅ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． ５，６，７，８−テトラヒドロ−６−［ｎ，ｎ−ビス［（２−チエニル）エチル］］アミノ−１−ナフトール、及びその作製方法、及びその使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2983729A (en) * 1958-04-30 1961-05-09 Monsanto Chemicals Preparation of 5-halothienyl amines
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2300090A1 (fr) * 1975-02-07 1976-09-03 Parcor Procede de preparation de derives de la thienopyridine
FR2315274A1 (fr) * 1975-06-27 1977-01-21 Parcor Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
IT1082336B (it) * 1977-01-27 1985-05-21 Medea Res Srl Processo per la preparazione della 5.2.clorobenzil.4 5 6 7.tetraidro tien 3 2.c.piridina

Also Published As

Publication number Publication date
EP0068978B1 (fr) 1986-09-03
JPS5810574A (ja) 1983-01-21
ES8305349A1 (es) 1983-04-01
GR76496B (cs) 1984-08-10
SU1148563A3 (ru) 1985-03-30
YU143382A (en) 1984-12-31
EP0068978A1 (fr) 1983-01-05
AU8475582A (en) 1983-01-06
IE821310L (en) 1982-12-30
ZA824624B (en) 1983-04-27
CA1205810A (en) 1986-06-10
NO822224L (no) 1983-01-03
CS248028B2 (en) 1987-01-15
NO155136B (no) 1986-11-10
US4482718A (en) 1984-11-13
PT75152B (fr) 1984-05-29
FR2508453B1 (cs) 1983-12-23
ES514221A0 (es) 1983-04-01
ATE21897T1 (de) 1986-09-15
IL65980A (en) 1985-12-31
KR840000536A (ko) 1984-02-25
DK286682A (da) 1982-12-31
FI822315L (fi) 1982-12-31
AU566802B2 (en) 1987-10-29
DE3273015D1 (en) 1986-10-09
IE53228B1 (en) 1988-09-14
FI822315A0 (fi) 1982-06-29
PT75152A (fr) 1982-07-01
FR2508453A1 (fr) 1982-12-31
NZ200852A (en) 1985-09-13
FI822315A7 (fi) 1982-12-31
IL65980A0 (en) 1982-09-30
NO155136C (no) 1987-02-18
HU194860B (en) 1988-03-28

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