DD209738A5 - Verfahren zur herstellung des impfstoffes gegen die marek'sche krankheit - Google Patents
Verfahren zur herstellung des impfstoffes gegen die marek'sche krankheit Download PDFInfo
- Publication number
- DD209738A5 DD209738A5 DD25008383A DD25008383A DD209738A5 DD 209738 A5 DD209738 A5 DD 209738A5 DD 25008383 A DD25008383 A DD 25008383A DD 25008383 A DD25008383 A DD 25008383A DD 209738 A5 DD209738 A5 DD 209738A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- vaccine
- virus
- spga
- yield
- strain
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 13
- 208000006758 Marek Disease Diseases 0.000 title claims abstract description 7
- 241000700605 Viruses Species 0.000 claims abstract description 18
- 241001502481 Meleagrid alphaherpesvirus 1 Species 0.000 claims abstract description 10
- 238000009210 therapy by ultrasound Methods 0.000 claims abstract description 9
- 238000004113 cell culture Methods 0.000 claims abstract description 7
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 6
- 235000021317 phosphate Nutrition 0.000 claims abstract description 6
- 239000013049 sediment Substances 0.000 claims abstract description 6
- 241000283690 Bos taurus Species 0.000 claims abstract description 5
- 101710184309 Probable sucrose-6-phosphate hydrolase Proteins 0.000 claims abstract description 5
- 102400000472 Sucrase Human genes 0.000 claims abstract description 5
- 101710112652 Sucrose-6-phosphate hydrolase Proteins 0.000 claims abstract description 5
- 230000000120 cytopathologic effect Effects 0.000 claims abstract description 5
- 235000011073 invertase Nutrition 0.000 claims abstract description 5
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims abstract description 5
- 241001465754 Metazoa Species 0.000 claims abstract description 4
- 244000144977 poultry Species 0.000 claims abstract description 4
- 239000000969 carrier Substances 0.000 claims abstract description 3
- 239000004005 microsphere Substances 0.000 claims abstract description 3
- 239000000725 suspension Substances 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 3
- 238000010790 dilution Methods 0.000 claims description 3
- 239000012895 dilution Substances 0.000 claims description 3
- 229920002307 Dextran Polymers 0.000 claims description 2
- 210000003837 chick embryo Anatomy 0.000 claims description 2
- 244000052769 pathogen Species 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 abstract description 5
- WDRWZVWLVBXVOI-QTNFYWBSSA-L dipotassium;(2s)-2-aminopentanedioate Chemical compound [K+].[K+].[O-]C(=O)[C@@H](N)CCC([O-])=O WDRWZVWLVBXVOI-QTNFYWBSSA-L 0.000 abstract description 4
- 235000013919 monopotassium glutamate Nutrition 0.000 abstract description 4
- 210000002257 embryonic structure Anatomy 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 241000287828 Gallus gallus Species 0.000 abstract description 2
- 210000004027 cell Anatomy 0.000 description 13
- 239000001963 growth medium Substances 0.000 description 4
- 238000000527 sonication Methods 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- 241000204031 Mycoplasma Species 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 241001529453 unidentified herpesvirus Species 0.000 description 2
- 208000029433 Herpesviridae infectious disease Diseases 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000012595 freezing medium Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 210000002064 heart cell Anatomy 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO107322A RO80570B1 (ro) | 1982-04-22 | 1982-04-22 | Procedeu de preparare a vaccinului contra bolii lui marek |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD209738A5 true DD209738A5 (de) | 1984-05-23 |
Family
ID=20111418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD25008383A DD209738A5 (de) | 1982-04-22 | 1983-04-21 | Verfahren zur herstellung des impfstoffes gegen die marek'sche krankheit |
Country Status (3)
| Country | Link |
|---|---|
| CS (1) | CS244931B2 (cs) |
| DD (1) | DD209738A5 (cs) |
| RO (1) | RO80570B1 (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RO132299A3 (ro) | 2017-06-06 | 2018-12-28 | Fântână Raul Sorin | Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active () |
-
1982
- 1982-04-22 RO RO107322A patent/RO80570B1/ro unknown
-
1983
- 1983-04-21 DD DD25008383A patent/DD209738A5/de unknown
- 1983-04-22 CS CS288883A patent/CS244931B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO80570A3 (ro) | 1984-07-17 |
| CS244931B2 (en) | 1986-08-14 |
| RO80570B1 (ro) | 1984-09-30 |
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