DD209818A5 - Verfahren zur herstellung von 5-phenylpyrazin-2-on-verbindungen und ihren salzen - Google Patents
Verfahren zur herstellung von 5-phenylpyrazin-2-on-verbindungen und ihren salzen Download PDFInfo
- Publication number
- DD209818A5 DD209818A5 DD25173683A DD25173683A DD209818A5 DD 209818 A5 DD209818 A5 DD 209818A5 DD 25173683 A DD25173683 A DD 25173683A DD 25173683 A DD25173683 A DD 25173683A DD 209818 A5 DD209818 A5 DD 209818A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- group
- general formula
- compound
- preparation
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8216437 | 1982-06-05 | ||
| GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD209818A5 true DD209818A5 (de) | 1984-05-23 |
Family
ID=26283037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD25173683A DD209818A5 (de) | 1982-06-05 | 1983-06-03 | Verfahren zur herstellung von 5-phenylpyrazin-2-on-verbindungen und ihren salzen |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4514568A (fr) |
| EP (1) | EP0096517A3 (fr) |
| KR (1) | KR840005111A (fr) |
| AU (1) | AU1527583A (fr) |
| DD (1) | DD209818A5 (fr) |
| DK (1) | DK247783A (fr) |
| ES (2) | ES522962A0 (fr) |
| FI (1) | FI831998L (fr) |
| GR (1) | GR79299B (fr) |
| JO (1) | JO1255B1 (fr) |
| NO (1) | NO832016L (fr) |
| PL (1) | PL242354A1 (fr) |
| PT (1) | PT76791B (fr) |
| RO (1) | RO86851B (fr) |
| ZW (1) | ZW12783A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
| JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | １−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EP2527360B1 (fr) | 2007-06-04 | 2015-10-28 | Synergy Pharmaceuticals Inc. | Agonistes de guanylase cyclase utiles pour le traitement de troubles gastro-intestinaux, d'inflammation, de cancer et d'autres troubles |
| EP2810951B1 (fr) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles |
| EP3241839B1 (fr) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
| JP2013502429A (ja) * | 2009-08-19 | 2013-01-24 | アムビト ビオスシエンセス コルポラチオン | ビアリール化合物及びその使用方法 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| ES2664873T3 (es) | 2011-03-01 | 2018-04-23 | Synergy Pharmaceuticals Inc. | Proceso de preparación de agonistas de guanilato ciclasa C |
| JP6215315B2 (ja) * | 2012-06-12 | 2017-10-18 | アッヴィ・インコーポレイテッド | ピリジノンおよびピリダジノン誘導体 |
| US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| CA2905435A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions utiles pour le traitement de troubles gastro-intestinaux |
| CA2905438A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
| SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
| KR102456567B1 (ko) | 2013-08-09 | 2022-10-19 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
| WO2020237096A1 (fr) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combinaison pour baisser le phosphate sérique chez un patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/fr not_active Withdrawn
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 FI FI831998A patent/FI831998L/fi not_active Application Discontinuation
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-03 ES ES522962A patent/ES522962A0/es active Granted
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Withdrawn
-
1984
- 1984-02-24 ES ES530024A patent/ES8707507A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES530024A0 (es) | 1985-12-01 |
| FI831998A7 (fi) | 1983-12-06 |
| RO86851B (ro) | 1985-05-31 |
| ZW12783A1 (en) | 1983-08-24 |
| NO832016L (no) | 1983-12-06 |
| PT76791A (en) | 1983-07-01 |
| FI831998L (fi) | 1983-12-06 |
| US4514568A (en) | 1985-04-30 |
| DK247783D0 (da) | 1983-06-01 |
| RO86851A (fr) | 1985-05-20 |
| ES8500244A1 (es) | 1984-10-01 |
| ES8707507A1 (es) | 1985-12-01 |
| PT76791B (en) | 1986-01-24 |
| US4556711A (en) | 1985-12-03 |
| PL242354A1 (en) | 1984-12-17 |
| EP0096517A2 (fr) | 1983-12-21 |
| FI831998A0 (fi) | 1983-06-03 |
| DK247783A (da) | 1983-12-06 |
| GR79299B (fr) | 1984-10-22 |
| KR840005111A (ko) | 1984-11-03 |
| JO1255B1 (en) | 1985-04-20 |
| AU1527583A (en) | 1983-12-08 |
| ES522962A0 (es) | 1984-10-01 |
| EP0096517A3 (fr) | 1985-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD209818A5 (de) | Verfahren zur herstellung von 5-phenylpyrazin-2-on-verbindungen und ihren salzen | |
| DE602004010848T2 (de) | Derivate von 1-piperazin- und 1-homopiperazincarboxylaten, verfahren zu deren herstellung und deren verwendung als inhibitoren des faah-enzyms | |
| EP0726899B1 (fr) | Nouveaux derives de pyrazinecarboxamide, leur preparation et leur utilisation dans des medicaments | |
| DE3781845T2 (de) | Benzimidazol-derivate. | |
| EP0175363B1 (fr) | 4,5-Dihydro-3(2H)-pyridazinones, procédé pour leur préparation et leur usage | |
| DD211555A5 (de) | Verfahren zur herstellung neuer 4-amino-6,7-dimethoxychinolin-derivate | |
| DD202152A5 (de) | Verfahren zur herstellung von phenylpiperazinderivaten | |
| DE2406930A1 (de) | Neue heterocyclische verbindungen und verfahren zu ihrer herstellung | |
| DE60006054T2 (de) | Herstellungsverfahren für Pyridinderivate | |
| EP0117403A1 (fr) | Dérivés de 6-(Acylaminoaryl)-3(2H)-pyridazinones, leur préparation et utilisation | |
| DE2825906A1 (de) | 3-(pyrazol-1'-yl)-pyridazinderivate, solche enthaltende arzneimittel und verfahren zur herstellung derselben | |
| DD286581A5 (de) | Verfahren zur herstellung von hetera-aliphatischem carbonsaeureamiden | |
| DE2224338A1 (de) | Oxadiazol Derivate | |
| DE3027106C2 (fr) | ||
| EP0018360B1 (fr) | N-(5-méthoxybenzofuran-2-ylcarbonyl)-N'-benzylpipérazine et procédé pour sa préparation | |
| DE1445675B2 (de) | Pyridylharnstoffe und verfahren zu ihrer herstellung | |
| DE2806661A1 (de) | Substituierte harnstoffe und verfahren zu ihrer herstellung | |
| DE2356239A1 (de) | Benzophenon-derivate und verfahren zu ihrer herstellung | |
| EP0224159B1 (fr) | Composés pyridiniques substitués par des groupes basiques, leur procédé de préparation, médicaments les contenant et leur application | |
| DE2215943A1 (de) | Neue 6-Phenyl-4H-s-triazolo eckige Klammer auf 1,5-a eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu benzodiazepin-2-carbonsäuren und ihre Ester, sowie Verfahren zu deren Herstellung | |
| US4657906A (en) | Heterocyclic compounds having inotropic activity | |
| DE2725019A1 (de) | Verfahren zur herstellung substituierter aminochinazolinderivate und zwischenprodukte dafuer | |
| DE2854112A1 (de) | Neue pyrido-pyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel | |
| CH647497A5 (en) | Process for the preparation of O-substituted hydroxylamines | |
| DE4239540A1 (de) | Neue heterocyclische Verbindungen mit antiasthmatischer/antiallergischer, entzündungshemmender, positiv inotroper und blutdrucksenkender Wirkung |