PL3004138T3 - Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie - Google Patents

Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie

Info

Publication number
PL3004138T3
PL3004138T3 PL14735048.2T PL14735048T PL3004138T3 PL 3004138 T3 PL3004138 T3 PL 3004138T3 PL 14735048 T PL14735048 T PL 14735048T PL 3004138 T3 PL3004138 T3 PL 3004138T3
Authority
PL
Poland
Prior art keywords
ultra
making
same
guanylate cyclase
pure agonists
Prior art date
Application number
PL14735048.2T
Other languages
English (en)
Inventor
Kunwar Shailubhai
Stephen Comiskey
Rong FENG
Juncai Bai
Ruoping Zhang
Jun JIA
Junfeng Zhou
Qiao ZHAO
Guoqing Zhang
Original Assignee
Bausch Health Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51062980&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3004138(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bausch Health Ireland Limited filed Critical Bausch Health Ireland Limited
Publication of PL3004138T3 publication Critical patent/PL3004138T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01002—Guanylate cyclase (4.6.1.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL14735048.2T 2013-06-05 2014-06-05 Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie PL3004138T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361831402P 2013-06-05 2013-06-05
PCT/US2014/041143 WO2014197720A2 (en) 2013-06-05 2014-06-05 Ultra-pure agonists of guanylate cyclase c, method of making and using same

Publications (1)

Publication Number Publication Date
PL3004138T3 true PL3004138T3 (pl) 2024-07-29

Family

ID=51062980

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14735048.2T PL3004138T3 (pl) 2013-06-05 2014-06-05 Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie

Country Status (17)

Country Link
US (8) US10011637B2 (pl)
EP (2) EP3004138B1 (pl)
JP (1) JP6606491B2 (pl)
KR (1) KR102272746B1 (pl)
CN (2) CN113388007A (pl)
AU (3) AU2014274812B2 (pl)
BR (1) BR112015030326A2 (pl)
CA (1) CA2913737C (pl)
EA (1) EA201592263A1 (pl)
ES (1) ES2981866T3 (pl)
HR (1) HRP20240805T1 (pl)
IL (1) IL242939B (pl)
PL (1) PL3004138T3 (pl)
PT (1) PT3004138T (pl)
RS (1) RS65632B1 (pl)
SI (1) SI3004138T1 (pl)
WO (1) WO2014197720A2 (pl)

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WO2008151257A2 (en) * 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2621509A4 (en) * 2010-09-15 2016-08-03 Synergy Pharmaceuticals Inc FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHOD OF USE
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
JP2016534043A (ja) * 2013-10-09 2016-11-04 シナジー ファーマシューティカルズ インコーポレイテッド 炎症促進性サイトカインのダウンレギュレーションに有用なグアニル酸シクラーゼのアゴニスト
CN104628827B (zh) * 2015-03-10 2018-01-19 南京工业大学 一种普利卡那肽的制备方法
US10618938B2 (en) * 2015-05-01 2020-04-14 Ironwood Pharmaceuticals, Inc. Compositions for colon cleansing and the treatment of gastrointestinal disorders
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CN108864254B (zh) * 2017-05-10 2021-03-16 深圳翰宇药业股份有限公司 一种普利卡那肽的制备方法
CN107383171A (zh) * 2017-08-15 2017-11-24 苏州科技大学 一种通过二次环化固相合成普卡那肽的方法
CN107383170A (zh) * 2017-08-15 2017-11-24 苏州科技大学 一种普卡那肽的简易合成方法
CN110835365B (zh) * 2018-08-15 2021-09-17 深圳翰宇药业股份有限公司 一种普卡那肽的制备方法
US12162957B2 (en) 2018-12-08 2024-12-10 Enzene Biosciences Limited Process for the preparation of plecanatide
JP7375012B2 (ja) * 2019-04-16 2023-11-07 サンゲン バイオサイエンス カンパニー,リミテッド ヒルジン突然変異体の抽出・精製方法およびその使用
WO2020250102A1 (en) * 2019-06-10 2020-12-17 Auro Peptides Ltd An improved process for the preparation of plecanatide
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
US20230242581A1 (en) * 2020-06-17 2023-08-03 Anthem Biosciences Private Limited Synthesis of a guanylate cyclase agonist by fragments based approach
JP7599014B2 (ja) * 2020-06-30 2024-12-12 オクヴィルク,ゼレン グアニル酸シクラーゼc(gucy2c)アゴニストおよび短鎖脂肪酸またはそのプロドラッグの組み合わせを含む医薬組成物
CN112194708A (zh) * 2020-10-28 2021-01-08 杭州信海医药科技有限公司 一种普卡那肽的制备方法
CN113244791B (zh) * 2021-05-12 2022-06-17 佳木斯大学 一种共混大黄素的酚酞聚醚砜超滤膜的制备方法
CN114573662B (zh) * 2021-09-30 2024-06-11 深圳翰宇药业股份有限公司 一种普卡那肽铵盐的制备方法
CN116789764B (zh) * 2023-05-30 2025-01-03 北京悦康科创医药科技股份有限公司 一种抗冠状病毒多肽的制备方法
CN117538461B (zh) * 2024-01-10 2024-03-26 地奥集团成都药业股份有限公司 一种盐酸贝那普利片有关物质的检测方法
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

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