DD272306A5 - Verfahren zur herstellung von peptidanalogen - Google Patents

Verfahren zur herstellung von peptidanalogen Download PDF

Info

Publication number
DD272306A5
DD272306A5 DD88316656A DD31665688A DD272306A5 DD 272306 A5 DD272306 A5 DD 272306A5 DD 88316656 A DD88316656 A DD 88316656A DD 31665688 A DD31665688 A DD 31665688A DD 272306 A5 DD272306 A5 DD 272306A5
Authority
DD
German Democratic Republic
Prior art keywords
nva
group
physiologically acceptable
compound
formula
Prior art date
Application number
DD88316656A
Other languages
German (de)
English (en)
Inventor
Jan O Karlsson
Erik M H Sohtell
Carl I Starke
Rolf Ch Westerlund
Original Assignee
�����@������������������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �����@������������������k�� filed Critical �����@������������������k��
Publication of DD272306A5 publication Critical patent/DD272306A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
DD88316656A 1986-12-29 1988-06-10 Verfahren zur herstellung von peptidanalogen DD272306A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8605573A SE8605573D0 (sv) 1986-12-29 1986-12-29 Novel compounds

Publications (1)

Publication Number Publication Date
DD272306A5 true DD272306A5 (de) 1989-10-04

Family

ID=20366760

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88316656A DD272306A5 (de) 1986-12-29 1988-06-10 Verfahren zur herstellung von peptidanalogen

Country Status (13)

Country Link
EP (1) EP0273893A3 (fr)
JP (1) JPH02501735A (fr)
KR (1) KR890700131A (fr)
CN (1) CN1039017A (fr)
AU (1) AU600549B2 (fr)
DD (1) DD272306A5 (fr)
DK (1) DK469588A (fr)
FI (1) FI893155L (fr)
HU (1) HUT49892A (fr)
NO (1) NO883818L (fr)
SE (1) SE8605573D0 (fr)
WO (1) WO1988005049A1 (fr)
ZA (1) ZA883315B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8802428D0 (sv) * 1988-06-28 1988-06-28 Haessle Ab New compounds
DE3841732A1 (de) * 1988-12-10 1990-06-13 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
US5215968A (en) * 1988-12-10 1993-06-01 Hoechst Aktiengesellschaft Dipeptide derivatives having an enzyme inhibitory action
US5198426A (en) * 1988-12-30 1993-03-30 Warner-Lambert Company Renin inhibitors containing c-terminal dihydroxy amides
AU7032391A (en) * 1989-12-22 1991-07-24 Astra Aktiebolag New amides
DE4004898A1 (de) * 1990-02-16 1991-08-22 Merck Patent Gmbh Peptid-analoga

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT995110B (it) * 1973-08-01 1975-11-10 Snam Progetti Procedimento per la produzione di composti eterociclici e prodotti ottenuti
FI843837A7 (fi) * 1983-02-07 1984-09-28 Ab Haessle Entsyymi-inhibiittorit.
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
JPS60199884A (ja) * 1984-03-26 1985-10-09 Microbial Chem Res Found ベスタチン類の新規製造法
EP0163237A3 (fr) * 1984-05-29 1988-04-27 Merck & Co. Inc. Inhibiteurs di- et tri-peptidiques de la rénine
US4645759A (en) * 1984-06-22 1987-02-24 Abbott Laboratories Renin inhibiting compounds
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
DK356085A (da) * 1984-08-06 1986-02-07 Upjohn Co Reninhaemmende peptid eller et farmaceutisk acceptabelt syreadditionssalt deraf
EP0258289A4 (en) * 1986-01-16 1991-01-02 Joseph Dellaria Peptide analogs

Also Published As

Publication number Publication date
KR890700131A (ko) 1989-03-10
AU1108488A (en) 1988-07-27
FI893155A0 (fi) 1989-06-28
NO883818D0 (no) 1988-08-26
ZA883315B (en) 1990-01-31
FI893155A7 (fi) 1989-06-28
CN1039017A (zh) 1990-01-24
DK469588D0 (da) 1988-08-22
HUT49892A (en) 1989-11-28
DK469588A (da) 1988-08-22
EP0273893A3 (fr) 1988-09-21
SE8605573D0 (sv) 1986-12-29
JPH02501735A (ja) 1990-06-14
AU600549B2 (en) 1990-08-16
NO883818L (no) 1988-08-26
EP0273893A2 (fr) 1988-07-06
WO1988005049A1 (fr) 1988-07-14
FI893155L (fi) 1989-06-28

Similar Documents

Publication Publication Date Title
EP0184550B1 (fr) Dérivés de 5-amino-4-hydroxy valérylamides
DE3689314T2 (de) Peptidasehemmungsmittel.
DE3689508T2 (de) Peptide.
CH676988A5 (fr)
EP0143746A2 (fr) Dérivés 5-amino 4-hydroxy-valeryl-substitués
JPH0437070B2 (fr)
EP0796271B1 (fr) p-amidinobenzylamides dipeptidiques a restes n-terminaux sulfonyle ou aminosulfonyle
US4386073A (en) Tripeptides acting on the central nervous system and a process for the preparation thereof
EP0417698B1 (fr) Dérivés d'acides aminés à activité inhibitrice de la rénine, procédé pour leur préparation, agents les contenant et leur utilisation
DE3418491A1 (de) Diaminosaeurederivate
EP0105102A1 (fr) Dérivés d'acides 2-aza-bicyclo(2,2,2)-octane-3-carboxyliques, leur procédé de préparation, les médicaments les contenant et leur application, ainsi que l'acide 2-aza-bicyclo(2,2,2)-octane-3-carboxylique comme intermédiaire et le procédé pour sa préparation
DE69431359T2 (de) Prolyl-endopeptidaseinhibitoren
DE60008218T2 (de) Heterozyklische verbindungen, ihre zwischenprodukte und elastase-inhibitoren
DE69510338T2 (de) Azirdin-derivate, deren herstellung und verwendung
CH676003A5 (fr)
EP0374098A2 (fr) Inhibiteurs de protéase rétrovirale
DE69122266T2 (de) Antivirale verbindungen
EP0144290A2 (fr) Dérivés éthylènediamine substitués
DE69304573T2 (de) Aminsäurederivate mit antithrombotischer Wirkung
DD272306A5 (de) Verfahren zur herstellung von peptidanalogen
EP0198271B1 (fr) Peptides
DE3787042T2 (de) Tripeptid-Derivate.
EP0320753A2 (fr) Dérivés d'aminoacides cycliques, procédé pour leur préparation, compositions les contenant et leur utilisation
EP0286927A2 (fr) Dérivés de pyrrolidine-2-(1,3-dicarbonyl), procédé pour leur préparation, agents les contenant ainsi que leur utilisation
DE3850818T2 (de) Fluor enthaltende Renin-Inhibitoren.

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee