DD289470A5 - Verfahren zur herstellung eines arzneimittels mit einem gehalt an gamma-interferon - Google Patents

Verfahren zur herstellung eines arzneimittels mit einem gehalt an gamma-interferon Download PDF

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Publication number
DD289470A5
DD289470A5 DD88321429A DD32142988A DD289470A5 DD 289470 A5 DD289470 A5 DD 289470A5 DD 88321429 A DD88321429 A DD 88321429A DD 32142988 A DD32142988 A DD 32142988A DD 289470 A5 DD289470 A5 DD 289470A5
Authority
DD
German Democratic Republic
Prior art keywords
interferon
liquid
buffer
agent
preparation
Prior art date
Application number
DD88321429A
Other languages
German (de)
English (en)
Inventor
Jiin-Yu Hwang-Felgner
Richard E Jones
James F Maher
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD289470A5 publication Critical patent/DD289470A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DD88321429A 1987-11-03 1988-11-03 Verfahren zur herstellung eines arzneimittels mit einem gehalt an gamma-interferon DD289470A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11643487A 1987-11-03 1987-11-03

Publications (1)

Publication Number Publication Date
DD289470A5 true DD289470A5 (de) 1991-05-02

Family

ID=22367187

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88321429A DD289470A5 (de) 1987-11-03 1988-11-03 Verfahren zur herstellung eines arzneimittels mit einem gehalt an gamma-interferon

Country Status (15)

Country Link
EP (1) EP0386106B1 (fr)
JP (1) JP2732877B2 (fr)
KR (1) KR890701135A (fr)
AU (1) AU621327B2 (fr)
CA (1) CA1335176C (fr)
DD (1) DD289470A5 (fr)
DE (1) DE3888197T2 (fr)
HK (1) HK29496A (fr)
HU (1) HU210530A9 (fr)
IE (1) IE60875B1 (fr)
IL (1) IL88233A (fr)
NZ (1) NZ226791A (fr)
PT (1) PT88918B (fr)
WO (1) WO1989004177A1 (fr)
ZA (1) ZA888249B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981485A (en) 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
IT1246296B (it) * 1990-07-25 1994-11-17 Sclavo Spa Procedimento di estrzione e purificazione del gamma interferone umano ricombinante
IL109350A (en) * 1993-05-12 2001-01-28 Genentech Inc Stable liquid compositions of gamma interferon
TW249202B (fr) * 1993-08-13 1995-06-11 Ciba Gerigy Corp
IT1272252B (it) 1994-05-16 1997-06-16 Applied Research Systems Formulazioni liquide di interferone beta
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
PT814841E (pt) * 1995-03-21 2002-03-28 Applied Research Systems Formulacoes liquidas de hcg
JP2758154B2 (ja) * 1995-04-06 1998-05-28 エフ・ホフマン−ラ ロシユ アーゲー インターフェロンを含む液体製剤
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
JPH1149698A (ja) 1997-07-31 1999-02-23 Santen Pharmaceut Co Ltd 安定性を向上させたラクトフェリンの水性製剤
JP5030329B2 (ja) * 1998-04-02 2012-09-19 ジェネンテック， インコーポレイテッド 心臓肥大の処置
LT4947B (lt) 2001-09-26 2002-08-26 Biotechnologijos Institutas Interferono alfa farmacinė kompozicija
WO2003026686A1 (fr) * 2001-09-27 2003-04-03 Pomytkin Igor A Potentialisation des effets therapeutiques des interferons
CU23432B6 (es) 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras
JP5137055B2 (ja) * 2006-03-10 2013-02-06 塩野義製薬株式会社 安定化されたインターフェロン−γ組成物
DE102007050165B4 (de) * 2007-10-19 2010-06-17 Stiftung Tierärztliche Hochschule Hannover Stabilisierte Lösung, Verfahren zu deren Herstellung sowie deren Verwendung und Arzneimittel in Form einer stabilisierten Lösung
JP2009091363A (ja) * 2008-11-21 2009-04-30 Asahi Kasei Pharma Kk Ｐｔｈの安定化水溶液注射剤
RU2564951C1 (ru) * 2014-08-28 2015-10-10 Закрытое акционерное общество "Вектор-Медика" (ЗАО "Вектор-Медика") Композиция водного раствора рекомбинантного интерферона альфа-2 человека для ректального применения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2834605A1 (de) * 1978-08-07 1980-02-28 Henkel Kgaa Neue bis-aminopyridine, deren herstellung und verwendung als komponenten in oxidationshaarfarben sowie diese enthaltende haarfaerbemittel
EP0080879B1 (fr) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Composition pharmaceutique contenant de l'interféron stabilisé
JPS59175416A (ja) * 1983-03-25 1984-10-04 Sunstar Inc 皮膚および粘膜の角化異常治療用外用剤
JPS61277633A (ja) * 1985-05-31 1986-12-08 Toray Ind Inc インタ−フエロン組成物
DE3628468A1 (de) * 1986-08-21 1988-03-03 Thomae Gmbh Dr K Neue applikationsformen fuer (alpha)-interferone

Also Published As

Publication number Publication date
IE883295L (en) 1989-05-03
IL88233A (en) 1993-08-18
PT88918B (pt) 1993-01-29
EP0386106A1 (fr) 1990-09-12
AU621327B2 (en) 1992-03-12
DE3888197D1 (de) 1994-04-07
NZ226791A (en) 1990-04-26
HU210530A9 (en) 1995-04-28
IE60875B1 (en) 1994-08-24
HK29496A (en) 1996-02-23
JP2732877B2 (ja) 1998-03-30
ZA888249B (en) 1990-07-25
EP0386106B1 (fr) 1994-03-02
PT88918A (pt) 1988-12-01
CA1335176C (fr) 1995-04-11
IL88233A0 (en) 1989-06-30
JPH03500882A (ja) 1991-02-28
DE3888197T2 (de) 1994-08-18
AU2724588A (en) 1989-06-01
WO1989004177A1 (fr) 1989-05-18
KR890701135A (ko) 1989-12-19

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Expiry date: 20081104