DE60006151D1 - Tocotrienole und geranylgeraniol aus nebenprodukten von bixa orellana - Google Patents

Tocotrienole und geranylgeraniol aus nebenprodukten von bixa orellana

Info

Publication number
DE60006151D1
DE60006151D1 DE60006151T DE60006151T DE60006151D1 DE 60006151 D1 DE60006151 D1 DE 60006151D1 DE 60006151 T DE60006151 T DE 60006151T DE 60006151 T DE60006151 T DE 60006151T DE 60006151 D1 DE60006151 D1 DE 60006151D1
Authority
DE
Germany
Prior art keywords
geranylgeraniol
component
tocotrienole
products
bixa orellana
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60006151T
Other languages
English (en)
Other versions
DE60006151T2 (de
Inventor
Barrie Tan
John Foley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American River Nutrition Inc
Original Assignee
American River Nutrition Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22468222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60006151(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American River Nutrition Inc filed Critical American River Nutrition Inc
Publication of DE60006151D1 publication Critical patent/DE60006151D1/de
Application granted granted Critical
Publication of DE60006151T2 publication Critical patent/DE60006151T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/80—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60006151T 1999-05-24 2000-05-24 Tocotrienole und geranylgeraniol aus nebenprodukten von bixa orellana Expired - Lifetime DE60006151T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13546399P 1999-05-24 1999-05-24
US135463P 1999-05-24
PCT/US2000/014212 WO2000071531A1 (en) 1999-05-24 2000-05-24 Tocotrienols and geranylgeraniol from bixa orellana byproducts

Publications (2)

Publication Number Publication Date
DE60006151D1 true DE60006151D1 (de) 2003-11-27
DE60006151T2 DE60006151T2 (de) 2004-07-22

Family

ID=22468222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006151T Expired - Lifetime DE60006151T2 (de) 1999-05-24 2000-05-24 Tocotrienole und geranylgeraniol aus nebenprodukten von bixa orellana

Country Status (7)

Country Link
US (1) US6350453B1 (de)
EP (1) EP1235822B1 (de)
AT (1) ATE252571T1 (de)
AU (1) AU5041400A (de)
DE (1) DE60006151T2 (de)
ES (1) ES2209890T3 (de)
WO (1) WO2000071531A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE355279T1 (de) 1998-08-07 2006-03-15 Novartis Vaccines & Diagnostic Pyrazole als modulatoren des östrogenrezeptors
US20030104090A1 (en) * 2000-05-05 2003-06-05 Levy Pedro E. Supplements containing annatto extracts and carotenoids and methods for using the same
US6838104B2 (en) 2000-12-20 2005-01-04 Archer Daniels Midland Company Process for the production of tocotrienols
CA2521149C (en) * 2003-04-08 2014-03-25 Barrie Tan Annatto extract compositions, including geranyl geraniols and methods of use
US7989006B2 (en) * 2003-04-08 2011-08-02 American River Nutrition, Inc. Annatto extract compositions, including geranyl geraniols and methods of use
CA2521020C (en) * 2003-04-10 2021-04-27 Barrie Tan Annatto extract compositions including tocotrienols and tocopherols and methods of use
US20050037102A1 (en) * 2003-07-18 2005-02-17 Barrie Tan Annatto extract compositions including tocotrienols and tocopherols and methods of use
US8586109B2 (en) * 2003-04-10 2013-11-19 American River Nutrition, Inc. Annatto extract compositions including tocotrienols and tocopherols and methods of use
JP2007238508A (ja) * 2006-03-09 2007-09-20 Tama Seikagaku Kk ゲラニルゲラニオールの製造方法
BRPI1000300A2 (pt) * 2010-01-29 2011-09-20 José Dos Reis Aloísio extrato vegetal promotor de cicatrização da epiderme e das mucosas, para uso tópico e por via oral
US20130158106A1 (en) 2010-06-02 2013-06-20 The United States Of America As Represented By The Department Of Veteran Affairs Tocopherol derivatives and methods of use
US8759547B2 (en) 2011-08-04 2014-06-24 Ramaswamy Rajendran Extraction of vitamin E from plant matter
US9039898B2 (en) 2011-11-15 2015-05-26 Engineering Research Associates, Inc. Method for separating components in natural oil
ES2394338B1 (es) * 2012-11-30 2013-12-09 Universidad De Granada Procedimiento de obtención de all-trans-geranilgeraniol
KR20160068776A (ko) 2013-09-13 2016-06-15 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 방사선 효과의 완화 및 예방을 위한 조성물의 제조 및 용도
TW201623271A (zh) 2014-02-11 2016-07-01 贏創薄膜萃取技術公司 從天然油製造富含維生素ｅ，尤其是富含生育三烯醇，之組成物的方法
US20160324914A1 (en) 2015-05-05 2016-11-10 Tocol Pharmaceuticals, Llc Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation
US11116210B2 (en) * 2017-11-10 2021-09-14 American River Nutrition, Llc Annatto extracts for insect repellency, larvicidal activity and methods of use
BR102019027219A2 (pt) * 2019-12-19 2021-06-29 Universidade Estadual De Campinas - Unicamp Complexo oleaginoso a partir da semente de urucum e seus usos
IT202100011825A1 (it) 2021-05-07 2022-11-07 Effegilab Srl Kit per la prevenzione ed il trattamento dell’invecchiamento cutaneo e sistemico e metodo cosmetico
WO2025064994A1 (en) * 2023-09-22 2025-03-27 American River Nutrition, Llc High purity geranylgeraniol and tocotrienol, methods of preparations and uses thereof

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2486541A (en) 1946-07-19 1949-11-01 Distillation Products Inc Delta-tocopherol
US4603142A (en) 1984-06-01 1986-07-29 Wisconsin Alumni Research Foundation Cholesterol lowering method of use
JPS6396155A (ja) 1986-10-13 1988-04-27 Kuraray Co Ltd 新規なテルペン化合物およびこれを含有する抗炎症剤
JPS63250315A (ja) 1987-04-03 1988-10-18 Shiseido Co Ltd 意識水準を高揚させる組成物
KR910007523A (ko) 1989-10-04 1991-05-30 브리스톨-마이어즈 스퀴브 컴페니 과콜레스테린혈증, 과지방혈증 및 혈전색전증 질병 치료용 토코트리엔올
US5217992A (en) 1989-10-04 1993-06-08 Bristol-Myers Squibb Company Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
US5157132A (en) 1990-05-18 1992-10-20 Carotech Associates Integrated process for recovery of carotenoids and tocotrienols from oil
US5393776A (en) 1990-09-14 1995-02-28 Bristol-Myers Squibb Company Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
CA2124086A1 (en) 1991-11-22 1993-05-27 Ronald H. Lane Tocotrienols and tocotrienol-like compounds and methods for their use
US5602184A (en) 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
US5318993A (en) 1993-04-16 1994-06-07 Bristol-Myers Squibb Company Antihyperlipidemic benzoquinones
JPH07188119A (ja) 1993-12-24 1995-07-25 Takasago Internatl Corp アミン誘導体およびその製造方法
JP3657298B2 (ja) 1994-11-08 2005-06-08 株式会社クラレ ゲラニルゲラニオ−ルの製造方法
US5660691A (en) 1995-11-13 1997-08-26 Eastman Chemical Company Process for the production of tocotrienol/tocopherol blend concentrates
JPH09238692A (ja) 1996-03-05 1997-09-16 Mitsui Petrochem Ind Ltd ゲラニルゲラニオールおよびその誘導体の生産性向上方法
US5670668A (en) 1996-07-03 1997-09-23 Eastman Chemical Company Crystalline tocotrienol esters
JPH1025226A (ja) 1996-07-10 1998-01-27 Kao Corp 養毛・育毛料
JPH1087480A (ja) 1996-09-13 1998-04-07 Eisai Co Ltd 抗動脈硬化治療剤
US5756109A (en) 1996-09-27 1998-05-26 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing geranyl geraniol and retinol or retinyl esters
JPH11130670A (ja) 1997-10-27 1999-05-18 Oyo Seikagaku Kenkyusho 骨粗鬆症治療剤
JP2002501916A (ja) 1998-01-29 2002-01-22 イーストマン ケミカル カンパニー トコール含有混合物からのトコトリエノールの分離方法及びその組成物
EP1089731A4 (de) 1998-06-24 2003-06-18 Merck & Co Inc Zusammensetzungen und verfahren zur behandlung von erhöhtem blutcholesterolspiegel

Also Published As

Publication number Publication date
AU5041400A (en) 2000-12-12
US6350453B1 (en) 2002-02-26
EP1235822A1 (de) 2002-09-04
ATE252571T1 (de) 2003-11-15
EP1235822B1 (de) 2003-10-22
WO2000071531A1 (en) 2000-11-30
ES2209890T3 (es) 2004-07-01
DE60006151T2 (de) 2004-07-22

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