DK0404440T3 - Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdomme - Google Patents
Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdommeInfo
- Publication number
- DK0404440T3 DK0404440T3 DK90306500.1T DK90306500T DK0404440T3 DK 0404440 T3 DK0404440 T3 DK 0404440T3 DK 90306500 T DK90306500 T DK 90306500T DK 0404440 T3 DK0404440 T3 DK 0404440T3
- Authority
- DK
- Denmark
- Prior art keywords
- asthma
- arthritis
- treatment
- substituted sulfonamides
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010003246 arthritis Diseases 0.000 title 1
- 208000006673 asthma Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
- GWNVDXQDILPJIG-SHSCPDMUSA-N Leukotriene C4 Natural products CCCCCC=C/CC=C/C=C/C=C/C(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)C(O)CCCC(=O)O GWNVDXQDILPJIG-SHSCPDMUSA-N 0.000 abstract 1
- OTZRAYGBFWZKMX-SHSCPDMUSA-N Leukotriene E4 Natural products CCCCCC=C/CC=C/C=C/C=C/C(SCC(N)C(=O)O)C(O)CCCC(=O)O OTZRAYGBFWZKMX-SHSCPDMUSA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- GWNVDXQDILPJIG-NXOLIXFESA-N leukotriene C4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@@H](C(=O)NCC(O)=O)NC(=O)CC[C@H](N)C(O)=O GWNVDXQDILPJIG-NXOLIXFESA-N 0.000 abstract 1
- YEESKJGWJFYOOK-IJHYULJSSA-N leukotriene D4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@H](N)C(=O)NCC(O)=O YEESKJGWJFYOOK-IJHYULJSSA-N 0.000 abstract 1
- OTZRAYGBFWZKMX-JUDRUQEKSA-N leukotriene E4 Chemical compound CCCCCC=CCC=C\C=C\C=C\[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O OTZRAYGBFWZKMX-JUDRUQEKSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/002748 WO1990015801A1 (en) | 1989-06-22 | 1989-06-22 | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0404440T3 true DK0404440T3 (da) | 1997-12-22 |
Family
ID=22215089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90306500.1T DK0404440T3 (da) | 1989-06-22 | 1990-06-14 | Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdomme |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0404440B1 (de) |
| JP (1) | JPH0753722B2 (de) |
| AT (1) | ATE159941T1 (de) |
| CA (1) | CA2019349A1 (de) |
| DE (1) | DE69031669T2 (de) |
| DK (1) | DK0404440T3 (de) |
| ES (1) | ES2109229T3 (de) |
| FI (1) | FI96951C (de) |
| GR (1) | GR3025697T3 (de) |
| IE (1) | IE902245A1 (de) |
| WO (1) | WO1990015801A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2053209C (en) * | 1990-10-12 | 1998-12-08 | Michel L. Belley | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
| JP2813464B2 (ja) * | 1992-01-23 | 1998-10-22 | フアイザー・インコーポレイテツド | ベンゾピラン及び関連ｌｔｂ▲下４▼アンタゴニスト |
| MX9300312A (es) * | 1992-01-23 | 1993-07-31 | Pfizer | Antagonistas benzopiranicos y relacionado de ltb. |
| JPH07508534A (ja) * | 1992-10-21 | 1995-09-21 | フアイザー・インコーポレイテツド | ベンゼン縮合ヒドロキシ置換シクロアルキルおよびヘテロ環式化合物のスルホンアミド誘導体 |
| CN1046279C (zh) * | 1993-02-16 | 1999-11-10 | 宇部兴产株式会社 | 喹啉衍生物 |
| ES2084547B1 (es) * | 1993-07-12 | 1997-01-16 | Pfizer | Antagonistas benzopiranicos y relacionados de leucotrieno b4. |
| US5539128A (en) * | 1994-11-30 | 1996-07-23 | Pfizer Inc. | Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline |
| WO1997048694A1 (en) | 1996-06-20 | 1997-12-24 | Board Of Regents, The University Of Texas System | Compounds and methods for providing pharmacologically active preparations and uses thereof |
| NZ522928A (en) * | 2000-06-21 | 2005-05-27 | F | Benzothiazole derivatives |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| CN1956983B (zh) | 2004-05-24 | 2010-05-26 | 弗·哈夫曼-拉罗切有限公司 | 4-羟基-4-甲基-哌啶-1-甲酸(4-甲氧基-7-吗啉-4-基-苯并噻唑-2-基)-酰胺 |
| CA2586931C (en) | 2004-11-05 | 2013-08-06 | Paul Spurr | Process for preparation of isonicotinic acid derivatives |
| RU2412943C2 (ru) | 2005-03-23 | 2011-02-27 | Ф. Хоффманн-Ля Рош Аг | ПРОИЗВОДНЫЕ АЦЕТИЛЕНИЛ-ПИРАЗОЛО-ПИРИМИДИНА В КАЧЕСТВЕ АНТАГОНИСТОВ mGluR2 |
| ES2340321T3 (es) | 2005-09-27 | 2010-06-01 | F.Hoffmann-La Roche Ag | Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675405A (en) * | 1984-09-21 | 1987-06-23 | American Home Products Corporation | Quinoline compounds as antiallergic and antithrombotic agents |
| US4845105A (en) * | 1984-10-30 | 1989-07-04 | Roussel Uclaf | 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity |
| US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
| US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| GB8613592D0 (en) * | 1986-06-04 | 1986-07-09 | Roussel Lab Ltd | Chemical compounds |
| MX13485A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos |
-
1989
- 1989-06-22 WO PCT/US1989/002748 patent/WO1990015801A1/en not_active Ceased
-
1990
- 1990-06-14 ES ES90306500T patent/ES2109229T3/es not_active Expired - Lifetime
- 1990-06-14 DE DE69031669T patent/DE69031669T2/de not_active Expired - Fee Related
- 1990-06-14 DK DK90306500.1T patent/DK0404440T3/da active
- 1990-06-14 AT AT90306500T patent/ATE159941T1/de not_active IP Right Cessation
- 1990-06-14 EP EP90306500A patent/EP0404440B1/de not_active Expired - Lifetime
- 1990-06-20 CA CA002019349A patent/CA2019349A1/en not_active Abandoned
- 1990-06-21 IE IE224590A patent/IE902245A1/en unknown
- 1990-06-22 JP JP2165484A patent/JPH0753722B2/ja not_active Expired - Lifetime
-
1991
- 1991-12-20 FI FI916065A patent/FI96951C/fi active
-
1997
- 1997-12-17 GR GR970403348T patent/GR3025697T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2019349A1 (en) | 1990-12-22 |
| IE902245L (en) | 1990-12-22 |
| WO1990015801A1 (en) | 1990-12-27 |
| FI96951C (fi) | 1996-09-25 |
| EP0404440A3 (de) | 1992-01-08 |
| FI96951B (fi) | 1996-06-14 |
| IE902245A1 (en) | 1991-01-16 |
| GR3025697T3 (en) | 1998-03-31 |
| FI916065A0 (fi) | 1991-12-20 |
| DE69031669D1 (de) | 1997-12-11 |
| EP0404440B1 (de) | 1997-11-05 |
| EP0404440A2 (de) | 1990-12-27 |
| JPH0753722B2 (ja) | 1995-06-07 |
| DE69031669T2 (de) | 1998-03-05 |
| ES2109229T3 (es) | 1998-01-16 |
| ATE159941T1 (de) | 1997-11-15 |
| JPH0338569A (ja) | 1991-02-19 |
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