DK0432029T3 - Fremgangsmåde til fremstilling af synergistiner - Google Patents

Fremgangsmåde til fremstilling af synergistiner

Info

Publication number: DK0432029T3
Authority: DK; Denmark
Prior art keywords: synergistins; producing; pristinamycin; virginiamycin; dimethylamino
Prior art date: 1989-12-05

Application number

DK90403433.7T

Other languages

English (en)

Inventor

Jean-Marc Paris

Xavier Radisson

Jean-Pierre Bastart

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-05

Filing date

1990-12-04

Publication date

1994-03-28

1990-12-04 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1994-03-28 Application granted granted Critical

1994-03-28 Publication of DK0432029T3 publication Critical patent/DK0432029T3/da

Links

238000000034 method Methods 0.000 title abstract 2
MVTQIFVKRXBCHS-SMMNFGSLSA-N N-[(3S,6S,12R,15S,16R,19S,22S)-3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide (10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone Chemical compound CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c2coc(CC(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@H]1C)n2.CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H]2CC(=O)CCN2C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@@H]2CCCN2C1=O)c1ccccc1 MVTQIFVKRXBCHS-SMMNFGSLSA-N 0.000 abstract 1
YGXCETJZBDTKRY-UHFFFAOYSA-N Pristinamycin Component I A Natural products CC1OC(=O)C(C=2C=CC=CC=2)NC(=O)C2CC(=O)CCN2C(=O)C(CC=2C=CC(=CC=2)N(C)C)N(C)C(=O)C2CCCN2C(=O)C(CC)NC(=O)C1NC(=O)C1=NC=CC=C1O YGXCETJZBDTKRY-UHFFFAOYSA-N 0.000 abstract 1
108010015795 Streptogramin B Proteins 0.000 abstract 1
108010080702 Virginiamycin Proteins 0.000 abstract 1
239000004188 Virginiamycin Substances 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
230000008030 elimination Effects 0.000 abstract 1
238000003379 elimination reaction Methods 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
YGXCETJZBDTKRY-DZCVGBHJSA-N pristinamycin IA Chemical compound N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2CCC(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O YGXCETJZBDTKRY-DZCVGBHJSA-N 0.000 abstract 1
229960003842 virginiamycin Drugs 0.000 abstract 1
235000019373 virginiamycin Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compounds Of Unknown Constitution (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK90403433.7T 1989-12-05 1990-12-04 Fremgangsmåde til fremstilling af synergistiner DK0432029T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8916030A FR2655343B1 (fr)	1989-12-05	1989-12-05	Procede de preparation de synergistine.

Publications (1)

Publication Number	Publication Date
DK0432029T3 true DK0432029T3 (da)	1994-03-28

Family

ID=9388148

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90403433.7T DK0432029T3 (da)	1989-12-05	1990-12-04	Fremgangsmåde til fremstilling af synergistiner

Country Status (21)

Country	Link
US (1)	US5304642A (da)
EP (1)	EP0432029B1 (da)
JP (1)	JP3157171B2 (da)
KR (1)	KR0178386B1 (da)
AT (1)	ATE102216T1 (da)
AU (1)	AU630771B2 (da)
CA (1)	CA2031486C (da)
DE (1)	DE69007041T2 (da)
DK (1)	DK0432029T3 (da)
ES (1)	ES2062461T3 (da)
FI (1)	FI93457C (da)
FR (1)	FR2655343B1 (da)
HU (1)	HU208157B (da)
IE (1)	IE64391B1 (da)
IL (1)	IL96536A (da)
NO (1)	NO177855C (da)
NZ (1)	NZ236329A (da)
PT (1)	PT96094B (da)
RU (1)	RU2090563C1 (da)
TW (1)	TW213918B (da)
ZA (1)	ZA909725B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030036654A1 (en) *	1994-08-18	2003-02-20	Holt Dennis A.	Synthetic multimerizing agents
JP4883597B2 (ja) *	2001-01-19	2012-02-22	河村電器産業株式会社	ボックスの戸当たり部材
WO2003062773A1 (en) *	2002-01-24	2003-07-31	Pei Electronics, Inc.	Compact integrated infrared scene projector

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4669116A (en) *	1982-12-09	1987-05-26	Regents Of The University Of California	Non-linear echo cancellation of data signals
FR2549062B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549063B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549064B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines utiles pour la preparation de nouveaux medicaments antimicrobiens et leur preparation
FR2549065B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
NL8600815A (nl) *	1986-03-28	1987-10-16	At & T & Philips Telecomm	Inrichting voor het kompenseren van niet-lineaire vervorming in een te digitaliseren ingangssignaal en een echokompensatiestelsel voorzien van een dergelijke inrichting.

1989
- 1989-12-05 FR FR8916030A patent/FR2655343B1/fr not_active Expired - Lifetime
1990
- 1990-12-03 AU AU67705/90A patent/AU630771B2/en not_active Expired
- 1990-12-04 ZA ZA909725A patent/ZA909725B/xx unknown
- 1990-12-04 JP JP40399390A patent/JP3157171B2/ja not_active Expired - Fee Related
- 1990-12-04 HU HU908056A patent/HU208157B/hu unknown
- 1990-12-04 RU SU904831832A patent/RU2090563C1/ru active
- 1990-12-04 TW TW079110217A patent/TW213918B/zh active
- 1990-12-04 EP EP90403433A patent/EP0432029B1/fr not_active Expired - Lifetime
- 1990-12-04 NO NO905241A patent/NO177855C/no not_active IP Right Cessation
- 1990-12-04 DE DE69007041T patent/DE69007041T2/de not_active Expired - Lifetime
- 1990-12-04 AT AT90403433T patent/ATE102216T1/de not_active IP Right Cessation
- 1990-12-04 IE IE437790A patent/IE64391B1/en not_active IP Right Cessation
- 1990-12-04 FI FI905992A patent/FI93457C/fi active IP Right Grant
- 1990-12-04 ES ES90403433T patent/ES2062461T3/es not_active Expired - Lifetime
- 1990-12-04 NZ NZ236329A patent/NZ236329A/xx unknown
- 1990-12-04 CA CA002031486A patent/CA2031486C/fr not_active Expired - Lifetime
- 1990-12-04 IL IL9653690A patent/IL96536A/en not_active IP Right Cessation
- 1990-12-04 KR KR1019900019851A patent/KR0178386B1/ko not_active Expired - Lifetime
- 1990-12-04 DK DK90403433.7T patent/DK0432029T3/da active
- 1990-12-05 PT PT96094A patent/PT96094B/pt not_active IP Right Cessation
1992
- 1992-07-02 US US07/908,928 patent/US5304642A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO177855B (no)	1995-08-28
AU6770590A (en)	1991-07-11
CA2031486C (fr)	2004-04-20
IL96536A0 (en)	1991-09-16
NO177855C (no)	1995-12-06
KR0178386B1 (ko)	1999-03-20
FI93457C (fi)	1995-04-10
CA2031486A1 (fr)	1991-06-06
FI93457B (fi)	1994-12-30
FI905992L (fi)	1991-06-06
KR910011863A (ko)	1991-08-07
FR2655343B1 (fr)	1992-05-07
FR2655343A1 (fr)	1991-06-07
PT96094A (pt)	1991-09-30
TW213918B (da)	1993-10-01
US5304642A (en)	1994-04-19
DE69007041D1 (de)	1994-04-07
EP0432029B1 (fr)	1994-03-02
JPH0436285A (ja)	1992-02-06
IL96536A (en)	1995-03-15
FI905992A0 (fi)	1990-12-04
EP0432029A1 (fr)	1991-06-12
RU2090563C1 (ru)	1997-09-20
IE64391B1 (en)	1995-08-09
HU208157B (en)	1993-08-30
HU908056D0 (en)	1991-06-28
NZ236329A (en)	1991-10-25
DE69007041T2 (de)	1994-06-23
HUT56119A (en)	1991-07-29
ATE102216T1 (de)	1994-03-15
PT96094B (pt)	1998-02-27
IE904377A1 (en)	1991-06-05
ZA909725B (en)	1991-10-30
ES2062461T3 (es)	1994-12-16
NO905241L (no)	1991-06-06
AU630771B2 (en)	1992-11-05
JP3157171B2 (ja)	2001-04-16
NO905241D0 (no)	1990-12-04

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EG20281A (en)	1998-07-30	Process for preparing heterocyclic cyclic amine derivatives useful in enhancing memory in patients suffering from dementia and alzheimer's disease
MY111616A (en)	2000-09-27	Nover (r)-5-carbamoyl-8-fluoro-3-n, n-disubstituted-amino-3, 4-dihydro-2h-1-benzopyrans
PL295030A1 (en)	1993-05-31	Method of obtaining substituted derivatives of 2-cyclohexan-1-yl amine
ES2123652T3 (es)	1999-01-16	7-(2-aminoetil)-benzotiazolonas.
CO4340623A1 (es)	1996-07-30	Derivados de indolina, metodo de preparacion y uso
DK502389A (da)	1989-11-20	Pyridazinonderivater og fremgangsmaade til fremstilling deraf
DK0532515T3 (da)	1997-04-21	Fremstilling af substituerede piperidiner
DE69207429D1 (de)	1996-02-15	Verfahren zur herstellung von substituierten piperidinen
DE3668621D1 (de)	1990-03-08	Verfahren zur herstellung von pteridinderivaten.
DK0387821T3 (da)	1994-09-19	2-Alkyl-4-arylmethylchinoliner, deres anvendelse og lægemidler fremstillet hermed
PT90572A (pt)	1989-11-30	Processo para a preparacao de derivados de 6-fenil-3-piperazinilalquil-1h,3h-2,4-pirimidinadiona
DK0432029T3 (da)	1994-03-28	Fremgangsmåde til fremstilling af synergistiner
DE68912809D1 (de)	1994-03-17	Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin.
ATE277887T1 (de)	2004-10-15	Verfahren zur herstellung von 1,4-bis((2- (dimethylamino)ethyl amino)-5,8- dihydroxyanthracene-9,10-dion
DE50100698D1 (de)	2003-11-06	Verfahren zur Herstellung von 1,3,6-Hexantricarbonitril
KR970702879A (ko)	1997-06-10	신규한 테트라펩티드, 이들의 제조 방법 및 용도(Novel Tetrapeptides, Their Manufacture and Use)
DK0796256T3 (da)	2004-05-10	Fremgangsmåde til fremstilling af ranitidin
ATE112281T1 (de)	1994-10-15	Verfahren zur herstellung von streptograminderivaten.
DE3764330D1 (de)	1990-09-20	2,2;6,6-diethylen-3-oxo-17alpha-pregn-4-en-21, 17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharm. praeparate.
DK0521766T3 (da)	1995-02-20	Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
SE9704834D0 (sv)	1997-12-22	New process
DK0468063T3 (da)	1996-08-19	En-beholder fremgangsmåde til fremstilling af -L-asparatyl-L-phenylalanin-methylester, hydrochlorid
DK0650953T3 (da)	1997-12-29	Cykliske analoger af fedtsyremetabolitter, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem