DK0441349T3 - Pyrroloazepinderivater - Google Patents

Pyrroloazepinderivater

Info

Publication number: DK0441349T3
Authority: DK; Denmark
Prior art keywords: group; branched; linear; disclosed; hydrogen atom
Prior art date: 1990-02-07

Application number

DK91101616.0T

Other languages

English (en)

Inventor

Akira Mizuno

Hidetsura Cho

Mikiko Hamaguchi

Toshio Tatsuoka

Ishihara Takafumi

Original Assignee

Suntory Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-07

Filing date

1991-02-06

Publication date

1996-05-13

1991-02-06 Application filed by Suntory Ltd filed Critical Suntory Ltd

1996-05-13 Application granted granted Critical

1996-05-13 Publication of DK0441349T3 publication Critical patent/DK0441349T3/da

Links

CTVOZUFKICZROL-UHFFFAOYSA-N pyrrolo[3,2-b]azepine Chemical class C1=CC=CC2=NC=CC2=N1 CTVOZUFKICZROL-UHFFFAOYSA-N 0.000 title abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000006681 (C2-C10) alkylene group Chemical group 0.000 abstract 1
HCUOEKSZWPGJIM-YBRHCDHNSA-N (e,2e)-2-hydroxyimino-6-methoxy-4-methyl-5-nitrohex-3-enamide Chemical compound COCC([N+]([O-])=O)\C(C)=C\C(=N/O)\C(N)=O HCUOEKSZWPGJIM-YBRHCDHNSA-N 0.000 abstract 1
101001109689 Homo sapiens Nuclear receptor subfamily 4 group A member 3 Proteins 0.000 abstract 1
101000598778 Homo sapiens Protein OSCP1 Proteins 0.000 abstract 1
101001067395 Mus musculus Phospholipid scramblase 1 Proteins 0.000 abstract 1
102100022673 Nuclear receptor subfamily 4 group A member 3 Human genes 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004419 alkynylene group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000003386 piperidinyl group Chemical group 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK91101616.0T 1990-02-07 1991-02-06 Pyrroloazepinderivater DK0441349T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2613790		1990-02-07
JP02773991A JP3198117B2 (ja)	1990-02-07	1991-01-30	ピロロアゼピン誘導体

Publications (1)

Publication Number	Publication Date
DK0441349T3 true DK0441349T3 (da)	1996-05-13

Family

ID=26363881

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91101616.0T DK0441349T3 (da)	1990-02-07	1991-02-06	Pyrroloazepinderivater

Country Status (10)

Country	Link
US (3)	US5206239A (da)
EP (1)	EP0441349B1 (da)
JP (1)	JP3198117B2 (da)
KR (1)	KR100255131B1 (da)
AT (1)	ATE132497T1 (da)
AU (1)	AU642960B2 (da)
CA (1)	CA2035749C (da)
DE (1)	DE69115943T2 (da)
DK (1)	DK0441349T3 (da)
ES (1)	ES2084719T3 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3198117B2 (ja) *	1990-02-07	2001-08-13	サントリー株式会社	ピロロアゼピン誘導体
ATE236163T1 (de) *	1991-08-07	2003-04-15	Suntory Ltd	Pyrroloazepinverbindungen
AU655841B2 (en) *	1991-08-07	1995-01-12	Daiichi Suntory Pharma Co., Ltd	Pyrroloazepine derivative
JP3714685B2 (ja) *	1994-05-18	2005-11-09	第一サントリーファーマ株式会社	ハイメニアルディシン及びその誘導体並びにそれらの合成中間体の製造法並びにその合成中間体
US6355659B1 (en)	1994-07-29	2002-03-12	Laboratorios Del Dr. Esteve, S.A.	4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same
FR2723091B1 (fr) *	1994-07-29	1996-11-08	Esteve Labor Dr	Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
ES2179218T3 (es) *	1995-12-01	2003-01-16	Suntory Ltd	Derivados de pirroloacepina.
JPH10251258A (ja)	1997-03-14	1998-09-22	Suntory Ltd	ピロロアゼピン系化合物
JPH11193289A (ja)	1997-12-26	1999-07-21	Suntory Ltd	ピロールスルホンアミド誘導体
JPH11193290A (ja)	1997-12-26	1999-07-21	Suntory Ltd	ピロールスルホンアミド系化合物
JP4953826B2 (ja)	2007-01-05	2012-06-13	ソニー株式会社	情報処理装置、表示制御方法、およびプログラム

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3563979A (en) *	1966-10-21	1971-02-16	Upjohn Co	1,2,3,4,5,6 - hexahydroazepino(4,3 - b)indoles and 1,2,3,4,5,6-hexahydroazepino(3,2-b)indoles
US3573324A (en) *	1969-02-28	1971-03-30	Upjohn Co	2,3,4,5,10,10a-hexahydroazepino(2,3-b)indoles
US3573323A (en) *	1969-02-28	1971-03-30	Upjohn Co	1,2,3,4,5,10-hexahydroazepino(2,3-b)indoles
JPS62161786A (ja) *	1986-01-08	1987-07-17	Mitsubishi Chem Ind Ltd	ピロ−ル化合物
US4729996A (en) *	1986-05-29	1988-03-08	Harbor Branch Oceanographic Institution, Inc.	Antitumor compositions and their methods of use
DE3903368A1 (de) *	1989-02-04	1990-08-09	Basf Ag	Verfahren zur herstellung von kondensierten cyclischen amidinen
JP3198117B2 (ja) *	1990-02-07	2001-08-13	サントリー株式会社	ピロロアゼピン誘導体

1991
- 1991-01-30 JP JP02773991A patent/JP3198117B2/ja not_active Expired - Fee Related
- 1991-02-06 DK DK91101616.0T patent/DK0441349T3/da active
- 1991-02-06 AT AT91101616T patent/ATE132497T1/de not_active IP Right Cessation
- 1991-02-06 EP EP91101616A patent/EP0441349B1/en not_active Expired - Lifetime
- 1991-02-06 CA CA002035749A patent/CA2035749C/en not_active Expired - Fee Related
- 1991-02-06 AU AU70806/91A patent/AU642960B2/en not_active Ceased
- 1991-02-06 DE DE69115943T patent/DE69115943T2/de not_active Expired - Fee Related
- 1991-02-06 ES ES91101616T patent/ES2084719T3/es not_active Expired - Lifetime
- 1991-02-07 US US07/651,778 patent/US5206239A/en not_active Expired - Lifetime
1992
- 1992-12-09 US US07/987,703 patent/US5391731A/en not_active Expired - Fee Related
1994
- 1994-02-14 US US08/195,019 patent/US5416082A/en not_active Expired - Fee Related
1999
- 1999-05-20 KR KR1019990018369A patent/KR100255131B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH0597856A (ja)	1993-04-20
CA2035749A1 (en)	1991-08-08
ES2084719T3 (es)	1996-05-16
US5391731A (en)	1995-02-21
AU642960B2 (en)	1993-11-04
US5416082A (en)	1995-05-16
JP3198117B2 (ja)	2001-08-13
EP0441349A1 (en)	1991-08-14
DE69115943D1 (de)	1996-02-15
ATE132497T1 (de)	1996-01-15
EP0441349B1 (en)	1996-01-03
AU7080691A (en)	1991-08-08
CA2035749C (en)	2001-10-23
US5206239A (en)	1993-04-27
DE69115943T2 (de)	1996-11-14
KR100255131B1 (ko)	2000-04-15

Publication	Publication Date	Title
HU906029D0 (en)	1991-03-28	Process for the preparation of pleuromuthylyne derivatives
DE69028136D1 (de)	1996-09-26	Alkoxyiminoacetamid-Derivate und ihre Verwendung als pilztötendes Mittel
CA2161542A1 (en)	1995-08-31	Novel 5-Pyrrolyl-2-Pyridylmethylsulfinyl Benzimidazole Derivatives
ES2164241T3 (es)	2002-02-16	Compuestos pentaciclicos.
ATE132497T1 (de)	1996-01-15	Pyrroloazepinderivate
PT86770A (pt)	1988-03-01	Process for preparing benzophenone derivatives
PT916651E (pt)	2004-01-30	DERIVADOS DE áCIDO FENILALQUILCARBOXILICO
EP0719773A4 (en)	1997-04-02	IMIDAZOLIDINONE DERIVATIVES, THEIR ACID ADDITION SALTS AND THEREFORE AGENTS AGAINST SENILE DENTENCE
EP0555479A4 (da)	1994-02-09
DE69631521D1 (de)	2004-03-18	Propenonderivate
ATE30718T1 (de)	1987-11-15	Herstellung von 1-benzyl azetidin-3-ol und von dem entsprechenden halid acid.
DE69311999D1 (de)	1997-08-14	Verfahren zur Herstellung von Amino-Thiadiazolylacetylhaliden
DE69231244D1 (de)	2000-08-17	Pyrazolothiazolopyrimidin-derivate
ATE98635T1 (de)	1994-01-15	Sterisch gehinderte aminoverbindungen und verfahren zu deren herstellung.
ATE159525T1 (de)	1997-11-15	Kondensierte naphthyridinderivate
DE69127396D1 (de)	1997-10-02	Verfahren zur Herstellung von Dihydrofuranonderivaten