DK0451626T3 - Anvendelse af benzodiazepinforbindelser til fremstilling af et farmaceutisk præparat mod med excitatoriske aminosyrer forbundne forstyrrelser i centralnervesystemet - Google Patents

Anvendelse af benzodiazepinforbindelser til fremstilling af et farmaceutisk præparat mod med excitatoriske aminosyrer forbundne forstyrrelser i centralnervesystemet

Info

Publication number: DK0451626T3
Authority: DK; Denmark
Prior art keywords: amino acids; nervous system; central nervous; preparation; excitations
Prior art date: 1990-04-13

Application number

DK91104888.2T

Other languages

English (en)

Inventor

Leif Helth Jensen

Joergen Drejer

Frank Waetjen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-13

Filing date

1991-03-27

Publication date

1998-04-20

1991-03-27 Application filed by Neurosearch As filed Critical Neurosearch As

1998-04-20 Application granted granted Critical

1998-04-20 Publication of DK0451626T3 publication Critical patent/DK0451626T3/da

Links

239000003257 excitatory amino acid Substances 0.000 title abstract 2
230000002461 excitatory amino acid Effects 0.000 title abstract 2
125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
210000003169 central nervous system Anatomy 0.000 title 1
230000005284 excitation Effects 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
208000012902 Nervous system disease Diseases 0.000 abstract 1
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
229940049706 benzodiazepine Drugs 0.000 abstract 1
-1 benzodiazepine compound Chemical class 0.000 abstract 1
208000015114 central nervous system disease Diseases 0.000 abstract 1
125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Fats And Perfumes (AREA)

DK91104888.2T 1990-04-13 1991-03-27 Anvendelse af benzodiazepinforbindelser til fremstilling af et farmaceutisk præparat mod med excitatoriske aminosyrer forbundne forstyrrelser i centralnervesystemet DK0451626T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US50928490A	1990-04-13	1990-04-13

Publications (1)

Publication Number	Publication Date
DK0451626T3 true DK0451626T3 (da)	1998-04-20

Family

ID=24026006

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91104888.2T DK0451626T3 (da)	1990-04-13	1991-03-27	Anvendelse af benzodiazepinforbindelser til fremstilling af et farmaceutisk præparat mod med excitatoriske aminosyrer forbundne forstyrrelser i centralnervesystemet

Country Status (12)

Country	Link
EP (1)	EP0451626B1 (da)
JP (1)	JP3015129B2 (da)
AT (1)	ATE157873T1 (da)
CA (1)	CA2040242A1 (da)
DE (1)	DE69127572T2 (da)
DK (1)	DK0451626T3 (da)
ES (1)	ES2108017T3 (da)
FI (1)	FI911784L (da)
GR (1)	GR3025186T3 (da)
IE (1)	IE910939A1 (da)
NO (1)	NO911449L (da)
PT (1)	PT97365B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5317018A (en) *	1992-06-09	1994-05-31	Armin Walser	Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
DE69331761T2 (de) *	1992-07-24	2002-09-12	The Regents Of The University Of California, Oakland	Arzneimittel, die den durch ampa rezeptoren vermittelten synaptischen respons erhöhen
US5852008A (en) *	1995-01-24	1998-12-22	The Regents Of The University Of California	Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
DE19604919A1 (de) *	1996-02-01	1997-08-07	Schering Ag	Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
GB2316616A (en) *	1996-09-02	1998-03-04	Lilly Industries Ltd	Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MC1528A1 (fr) *	1982-07-21	1984-04-13	Hoffmann La Roche	Imidazobenzodiazepines
CA1327008C (en) *	1988-01-15	1994-02-15	Walter Merz	Anti-psychotic imidazobenzodiazepine

1991
- 1991-03-21 IE IE093991A patent/IE910939A1/en unknown
- 1991-03-27 ES ES91104888T patent/ES2108017T3/es not_active Expired - Lifetime
- 1991-03-27 AT AT91104888T patent/ATE157873T1/de not_active IP Right Cessation
- 1991-03-27 EP EP91104888A patent/EP0451626B1/en not_active Expired - Lifetime
- 1991-03-27 DE DE69127572T patent/DE69127572T2/de not_active Expired - Fee Related
- 1991-03-27 DK DK91104888.2T patent/DK0451626T3/da active
- 1991-04-11 CA CA002040242A patent/CA2040242A1/en not_active Abandoned
- 1991-04-12 FI FI911784A patent/FI911784L/fi not_active Application Discontinuation
- 1991-04-12 PT PT97365A patent/PT97365B/pt not_active IP Right Cessation
- 1991-04-12 JP JP3079900A patent/JP3015129B2/ja not_active Expired - Fee Related
- 1991-04-12 NO NO91911449A patent/NO911449L/no unknown
1997
- 1997-10-29 GR GR970402821T patent/GR3025186T3/el unknown

Also Published As

Publication number	Publication date
NO911449D0 (no)	1991-04-12
JPH04224516A (ja)	1992-08-13
NO911449L (no)	1991-10-14
FI911784A7 (fi)	1991-10-14
DE69127572T2 (de)	1998-01-22
ATE157873T1 (de)	1997-09-15
FI911784L (fi)	1991-10-14
ES2108017T3 (es)	1997-12-16
PT97365B (pt)	1998-08-31
DE69127572D1 (de)	1997-10-16
GR3025186T3 (en)	1998-02-27
EP0451626A3 (en)	1992-10-07
EP0451626A2 (en)	1991-10-16
JP3015129B2 (ja)	2000-03-06
EP0451626B1 (en)	1997-09-10
IE910939A1 (en)	1991-10-23
PT97365A (pt)	1992-01-31
CA2040242A1 (en)	1991-10-14
FI911784A0 (fi)	1991-04-12

Publication	Publication Date	Title
DE69032020D1 (de)	1998-03-12	N-Substituierte 4-Pyrimidinamine und -Pyrimidindiamine, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
EA200000592A1 (ru)	2000-12-25	Азаполициклические соединения, конденсированные с арилом
MA22014A1 (fr)	1991-07-01	Derives d'acides amines .
NO913750L (no)	1992-03-26	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater.
FI931370A0 (fi)	1993-03-26	Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
ATE169915T1 (de)	1998-09-15	Pyrimidindionderivate, deren herstellung und verwendung
DK26289A (da)	1989-07-22	Anvendelse af 1,4-disubstitueret piperidinyl til fremstilling af et farmaceutisk praeparat til behandling af insomnia
FI911784A0 (fi)	1991-04-12	Ny behandlingsmetod med benzodiazepinfoereningar.
AU583375B2 (en)	1989-04-27	2,4-diphenyl-1,3-dioxanes
ATE92315T1 (de)	1993-08-15	Aminosaeurederivate enthaltende antikonvulsive zusammensetzungen und verwendung dieser aminosaeurederivate.
NO861868L (no)	1986-11-11	Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-oksatian-derivater.
DE69827706D1 (de)	2004-12-30	5-(Heteroaryl)alkyl)-3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid (PBI) Derivate zur Behandlung von Störungen des zentralen Nervensystems
DK0578052T3 (da)	1996-06-17	Anvendelse af iminoderivater af etianaldehyd til fremstilling af et lægemiddel til behandling af hypertension
DE69619088D1 (de)	2002-03-21	Quinoxalin-Derivate zur Behandlung von Tinnitus
DE69327077D1 (de)	1999-12-30	Carbamoylpyrrolidon-Derivate zur Behandlung von Depressionen und cerebrovasculären Störungen
DE69622393D1 (de)	2002-08-22	Neue verwendung von pyrazolopyridinverbindungen