DK0460881T3 - Fremgangsmåde til fremstilling af bicycliske beta-lactamer - Google Patents

Fremgangsmåde til fremstilling af bicycliske beta-lactamer

Info

Publication number
DK0460881T3
DK0460881T3 DK91304975.5T DK91304975T DK0460881T3 DK 0460881 T3 DK0460881 T3 DK 0460881T3 DK 91304975 T DK91304975 T DK 91304975T DK 0460881 T3 DK0460881 T3 DK 0460881T3
Authority
DK
Denmark
Prior art keywords
beta
lactams
alkoxy
preparation
carba
Prior art date
Application number
DK91304975.5T
Other languages
Danish (da)
English (en)
Inventor
Marvin Joseph Miller
Matthew Alan Williams
Original Assignee
Univ Notre Dame Du Lac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Notre Dame Du Lac filed Critical Univ Notre Dame Du Lac
Application granted granted Critical
Publication of DK0460881T3 publication Critical patent/DK0460881T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/04—Preparation by forming the ring or condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK91304975.5T 1990-06-06 1991-06-03 Fremgangsmåde til fremstilling af bicycliske beta-lactamer DK0460881T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/534,073 US5051502A (en) 1990-06-06 1990-06-06 Rhodium catalyzed cyclization process for bicyclic β-lactams

Publications (1)

Publication Number Publication Date
DK0460881T3 true DK0460881T3 (da) 1995-12-18

Family

ID=24128598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91304975.5T DK0460881T3 (da) 1990-06-06 1991-06-03 Fremgangsmåde til fremstilling af bicycliske beta-lactamer

Country Status (14)

Country Link
US (2) US5051502A (fr)
EP (1) EP0460881B1 (fr)
JP (1) JPH04330075A (fr)
KR (1) KR920000760A (fr)
AT (1) ATE130612T1 (fr)
CA (1) CA2043939A1 (fr)
DE (1) DE69114765T2 (fr)
DK (1) DK0460881T3 (fr)
ES (1) ES2081434T3 (fr)
GR (1) GR3018615T3 (fr)
HK (1) HK43696A (fr)
HU (1) HU212569B (fr)
IE (1) IE911918A1 (fr)
IL (1) IL98350A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189158A (en) * 1991-03-20 1993-02-23 American Cyanamid Company 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
US5493018A (en) * 1994-01-25 1996-02-20 Merck & Co., Inc. Process for synthesizing carbapenem intermediates using a rhodium catalyst and lewis acid
KR100661081B1 (ko) * 2000-06-10 2006-12-26 동화약품공업주식회사 항바이러스제로 유용한 6-메틸니코틴아미드 유도체
DK1404642T3 (da) * 2001-07-06 2010-05-17 Basf Se Fremgangsmåde til fremstillimg af 7-amino-syn-3,5-dihydroxyheptansyrederivater, mellemprodukter derfor og fremgangsmåder til deres fremstilling

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174316A (en) * 1978-08-14 1979-11-13 Merck & Co., Inc. 4-Iodomethylazetidin-2-one
US4275207A (en) * 1978-08-14 1981-06-23 Merck & Co., Inc. Process for preparing 7-(1-hydroxyethyl)-3-(2-aminoethylthio)-1-carbadethiaceph-3-em-3-carboxylic acid and intermediate therefor
DE3509769A1 (de) * 1985-03-19 1986-09-25 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von carbapenemzwischenprodukten
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics

Also Published As

Publication number Publication date
DE69114765T2 (de) 1996-05-02
IL98350A0 (en) 1992-07-15
ATE130612T1 (de) 1995-12-15
KR920000760A (ko) 1992-01-29
GR3018615T3 (en) 1996-04-30
HK43696A (en) 1996-03-22
US5106968A (en) 1992-04-21
IL98350A (en) 1995-07-31
US5051502A (en) 1991-09-24
EP0460881A1 (fr) 1991-12-11
DE69114765D1 (de) 1996-01-04
HU212569B (en) 1996-08-29
ES2081434T3 (es) 1996-03-16
HUT58096A (en) 1992-01-28
HU911885D0 (en) 1991-12-30
JPH04330075A (ja) 1992-11-18
IE911918A1 (en) 1991-12-18
EP0460881B1 (fr) 1995-11-22
CA2043939A1 (fr) 1991-12-07

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