DK0468217T3 - Et bifunktionelt cosmid anvendeligt til kloning afactinomycete - Google Patents

Et bifunktionelt cosmid anvendeligt til kloning afactinomycete

Info

Publication number: DK0468217T3
Authority: DK; Denmark
Prior art keywords: tetracycline; cloning; useful; lividans; afactinomycete
Prior art date: 1990-07-26

Application number

DK91110589T

Other languages

Danish (da)

English (en)

Inventor

Michael J Ryan

Jason A Lotvin

Nancy Strathy

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-26

Filing date

1991-06-26

Publication date

1998-10-07

1991-06-26 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1998-10-07 Application granted granted Critical

1998-10-07 Publication of DK0468217T3 publication Critical patent/DK0468217T3/da

Links

238000010367 cloning Methods 0.000 title abstract 2
230000001588 bifunctional effect Effects 0.000 title 1
239000004098 Tetracycline Substances 0.000 abstract 4
229960002180 tetracycline Drugs 0.000 abstract 4
235000019364 tetracycline Nutrition 0.000 abstract 4
229930101283 tetracycline Natural products 0.000 abstract 4
150000003522 tetracyclines Chemical class 0.000 abstract 4
241000187398 Streptomyces lividans Species 0.000 abstract 3
239000004099 Chlortetracycline Substances 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 2
CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 2
229960004475 chlortetracycline Drugs 0.000 abstract 2
CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 2
235000019365 chlortetracycline Nutrition 0.000 abstract 2
239000013612 plasmid Substances 0.000 abstract 2
238000003786 synthesis reaction Methods 0.000 abstract 2
229920001817 Agar Polymers 0.000 abstract 1
108020004414 DNA Proteins 0.000 abstract 1
102000053602 DNA Human genes 0.000 abstract 1
241000588724 Escherichia coli Species 0.000 abstract 1
239000008272 agar Substances 0.000 abstract 1
238000000855 fermentation Methods 0.000 abstract 1
230000004151 fermentation Effects 0.000 abstract 1
238000004128 high performance liquid chromatography Methods 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Exhaust Gas Treatment By Means Of Catalyst (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK91110589T 1990-07-26 1991-06-26 Et bifunktionelt cosmid anvendeligt til kloning afactinomycete DK0468217T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US55804090A	1990-07-26	1990-07-26

Publications (1)

Publication Number	Publication Date
DK0468217T3 true DK0468217T3 (da)	1998-10-07

Family

ID=24227940

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91110589T DK0468217T3 (da)	1990-07-26	1991-06-26	Et bifunktionelt cosmid anvendeligt til kloning afactinomycete

Country Status (17)

Country	Link
EP (1)	EP0468217B1 (ja)
JP (1)	JPH0568573A (ja)
KR (1)	KR100193208B1 (ja)
AT (1)	ATE166391T1 (ja)
AU (1)	AU651982B2 (ja)
CA (1)	CA2047837A1 (ja)
DE (1)	DE69129429T2 (ja)
DK (1)	DK0468217T3 (ja)
ES (1)	ES2117630T3 (ja)
HU (1)	HU217570B (ja)
IE (1)	IE912624A1 (ja)
IL (1)	IL98683A (ja)
NZ (1)	NZ239043A (ja)
PT (1)	PT98429B (ja)
SG (1)	SG43186A1 (ja)
TW (1)	TW229231B (ja)
ZA (1)	ZA915866B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0468220A3 (en) *	1990-07-26	1992-09-23	American Cyanamid Company	Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens & their expression in steptomyces lividans
US5589385A (en) *	1990-07-26	1996-12-31	American Cyanamid Company	Cloning of the biosynthetic pathway for chlortetracycline and tetracycline formation and cosmids useful therein
TW318189B (ja) *	1991-12-06	1997-10-21	American Cyanamid Co
US6524812B1 (en)	1993-10-07	2003-02-25	Regents Of The University Of Minnesota	Genes encoding resistance to DNA alkylating agents
US6495348B1 (en)	1993-10-07	2002-12-17	Regents Of The University Of Minnesota	Mitomycin biosynthetic gene cluster
US5989903A (en) *	1995-06-07	1999-11-23	American Cyanamid Company	Strain for the production of 6-dimethyltetracycline, method for producing the strain and vector for use in the method
US6265202B1 (en)	1998-06-26	2001-07-24	Regents Of The University Of Minnesota	DNA encoding methymycin and pikromycin
KR102203404B1 (ko)	2019-08-14	2021-01-15	권명오	반도체 설비의 배기라인 파우더 제거 장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5098837A (en) *	1988-06-07	1992-03-24	Eli Lilly And Company	Macrolide biosynthetic genes for use in streptomyces and other organisms
EP0468220A3 (en) *	1990-07-26	1992-09-23	American Cyanamid Company	Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens & their expression in steptomyces lividans

1991
- 1991-06-26 EP EP91110589A patent/EP0468217B1/en not_active Expired - Lifetime
- 1991-06-26 DK DK91110589T patent/DK0468217T3/da active
- 1991-06-26 ES ES91110589T patent/ES2117630T3/es not_active Expired - Lifetime
- 1991-06-26 DE DE69129429T patent/DE69129429T2/de not_active Expired - Fee Related
- 1991-06-26 AT AT91110589T patent/ATE166391T1/de not_active IP Right Cessation
- 1991-06-27 TW TW080104988A patent/TW229231B/zh not_active IP Right Cessation
- 1991-07-01 IL IL9868391A patent/IL98683A/en not_active IP Right Cessation
- 1991-07-19 NZ NZ239043A patent/NZ239043A/xx unknown
- 1991-07-24 CA CA002047837A patent/CA2047837A1/en not_active Abandoned
- 1991-07-24 PT PT98429A patent/PT98429B/pt not_active IP Right Cessation
- 1991-07-24 JP JP3206089A patent/JPH0568573A/ja active Pending
- 1991-07-25 AU AU81339/91A patent/AU651982B2/en not_active Ceased
- 1991-07-25 ZA ZA915866A patent/ZA915866B/xx unknown
- 1991-07-25 IE IE262491A patent/IE912624A1/en not_active IP Right Cessation
- 1991-07-26 HU HU515/91A patent/HU217570B/hu not_active IP Right Cessation
- 1991-07-26 KR KR1019910013059A patent/KR100193208B1/ko not_active Expired - Fee Related
1996
- 1996-08-27 SG SG1996005117A patent/SG43186A1/en unknown

Also Published As

Publication number	Publication date
HUT60776A (en)	1992-10-28
NZ239043A (en)	1993-09-27
HU217570B (hu)	2000-02-28
HU912515D0 (en)	1992-01-28
CA2047837A1 (en)	1992-01-27
ATE166391T1 (de)	1998-06-15
DE69129429D1 (de)	1998-06-25
IL98683A (en)	2002-11-10
EP0468217A3 (en)	1992-09-30
JPH0568573A (ja)	1993-03-23
SG43186A1 (en)	1997-10-17
ES2117630T3 (es)	1998-08-16
EP0468217A2 (en)	1992-01-29
AU651982B2 (en)	1994-08-11
KR920002777A (ko)	1992-02-28
PT98429B (pt)	1999-01-29
KR100193208B1 (ko)	1999-06-15
ZA915866B (en)	1992-04-29
EP0468217B1 (en)	1998-05-20
DE69129429T2 (de)	1998-09-24
IE912624A1 (en)	1992-01-29
PT98429A (pt)	1992-05-29
AU8133991A (en)	1992-01-30
IL98683A0 (en)	1992-07-15
TW229231B (ja)	1994-09-01

Publication	Publication Date	Title
DK221087D0 (da)	1987-04-30	Signalselektionsvektorer til extracellulaer prote- insyntese i baciller
AU3331989A (en)	1989-10-26	Insect-resistant lettuce plants
EA199900087A1 (ru)	1999-08-26	Новые эритромицины и способы их получения
DK0468217T3 (da)	1998-10-07	Et bifunktionelt cosmid anvendeligt til kloning afactinomycete
AU3529189A (en)	1989-12-07	Modified baculovirus, method for preparing it and its use as an expression vector of genes
NO900531L (no)	1990-08-07	Ekspresjonssystemer for amideringsenzymer.
CA2047833A1 (en)	1992-01-27	Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens and their expression in steptomyces lividans
CA2066370A1 (en)	1992-10-27	Yield when disulfide-bonded proteins are secreted
GR3030722T3 (en)	1999-11-30	Improved synthesis of bisindolylmaleimides.
EP0226979A3 (en)	1988-01-27	Process for producing the protein of an aequorin activity by using a photoprotein aequorin gene
ES2080719T3 (es)	1996-02-16	El operon gal de streptomyces.
DK0528955T3 (da)	1998-03-30	Proteasedeficiente bakterielle værtsorganismer
CZ20191998A3 (cs)	1998-09-16	Způsob selektivní ochrany derivátů baccatinu a jeho použití při syntéze taxanů
ES2071108T3 (es)	1995-06-16	Metodo eficiente para expresion identificable de genes no seleccionables.
CA2121481A1 (en)	1993-04-29	Expression of polypeptides in e.coli under control of the e.coli mdh-gene promoter
FI901372A0 (fi)	1990-03-19	Foerfarande foer framstaellning av 3-exometylenkefamsulfoxidderivat och deras mellanprodukter.
ATE87033T1 (de)	1993-04-15	Dactylocyclin a und dactylocyclin b.
DE69023544D1 (de)	1995-12-21	Teicoresistenz verleihende Sequenz.
AU652099C (en)	1996-12-19	Alkene intermediates for the production of certain 1,2-dioxetane compounds