DK0590150T3 - (-)-(S)-2,8-dimethyl-3-methylen-1-oxa-8-azaspiro[4,5]decan-L-tartrat - Google Patents
(-)-(S)-2,8-dimethyl-3-methylen-1-oxa-8-azaspiro[4,5]decan-L-tartratInfo
- Publication number
- DK0590150T3 DK0590150T3 DK92909279T DK92909279T DK0590150T3 DK 0590150 T3 DK0590150 T3 DK 0590150T3 DK 92909279 T DK92909279 T DK 92909279T DK 92909279 T DK92909279 T DK 92909279T DK 0590150 T3 DK0590150 T3 DK 0590150T3
- Authority
- DK
- Denmark
- Prior art keywords
- azaspiro
- oxa
- decane
- tartrate
- methylene
- Prior art date
Links
- RMKUOCBJRZODFU-LDGFUSNJSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;(2s)-2,8-dimethyl-3-methylidene-1-oxa-8-azaspiro[4.5]decane Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.C1C(=C)[C@H](C)OC21CCN(C)CC2 RMKUOCBJRZODFU-LDGFUSNJSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13961991 | 1991-05-15 | ||
| PCT/JP1992/000548 WO1992020683A1 (fr) | 1991-05-15 | 1992-04-27 | L-tartrate de (-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8-azaspiro[4,5]decane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0590150T3 true DK0590150T3 (da) | 1999-04-19 |
Family
ID=15249510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92909279T DK0590150T3 (da) | 1991-05-15 | 1992-04-27 | (-)-(S)-2,8-dimethyl-3-methylen-1-oxa-8-azaspiro[4,5]decan-L-tartrat |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5403931A (da) |
| EP (1) | EP0590150B1 (da) |
| AT (1) | ATE168114T1 (da) |
| AU (1) | AU1666392A (da) |
| CA (1) | CA2109117A1 (da) |
| DE (1) | DE69226187T2 (da) |
| DK (1) | DK0590150T3 (da) |
| ES (1) | ES2118814T3 (da) |
| GR (1) | GR3027686T3 (da) |
| RU (1) | RU2057132C1 (da) |
| WO (1) | WO1992020683A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100370697B1 (ko) * | 1993-08-19 | 2003-06-11 | 머크 앤드 캄파니 인코포레이티드 | 4'-데옥시-4'-에피-메틸아미노에버멕틴B1a/B1b벤조산염의순수한결정성반수화물형태B,이의제조방법및이를함유하는해충방제용조성물 |
| ES2368824T3 (es) * | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
| JP2003063964A (ja) * | 2001-08-28 | 2003-03-05 | Senju Pharmaceut Co Ltd | ドライアイまたはドライアイを伴なう疾病の予防治療剤 |
| US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| JPWO2007013661A1 (ja) * | 2005-07-26 | 2009-02-12 | 千寿製薬株式会社 | 眼科用経皮吸収型製剤 |
| WO2007025177A2 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| EP1942879A1 (en) | 2005-10-31 | 2008-07-16 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| BRPI0716604A2 (pt) | 2006-09-08 | 2013-04-09 | Braincells Inc | combinaÇÕes contendo um derivado de 4-acilaminopiridina |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| NZ594768A (en) * | 2009-01-26 | 2013-02-22 | Israel Inst Biolog Res | Bicyclic heterocyclic spiro compounds |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2074441T3 (es) * | 1987-10-05 | 1995-09-16 | Yamanouchi Pharma Co Ltd | Compuestos espiro heterociclicos y su preparacion. |
| US5075317A (en) * | 1989-06-21 | 1991-12-24 | Fisons Corporation | Spirofurane derivatives |
-
1992
- 1992-04-27 RU RU9293058306A patent/RU2057132C1/ru active
- 1992-04-27 CA CA002109117A patent/CA2109117A1/en not_active Abandoned
- 1992-04-27 US US08/146,133 patent/US5403931A/en not_active Expired - Fee Related
- 1992-04-27 DE DE69226187T patent/DE69226187T2/de not_active Expired - Fee Related
- 1992-04-27 AU AU16663/92A patent/AU1666392A/en not_active Abandoned
- 1992-04-27 EP EP92909279A patent/EP0590150B1/en not_active Expired - Lifetime
- 1992-04-27 ES ES92909279T patent/ES2118814T3/es not_active Expired - Lifetime
- 1992-04-27 DK DK92909279T patent/DK0590150T3/da active
- 1992-04-27 AT AT92909279T patent/ATE168114T1/de not_active IP Right Cessation
- 1992-04-27 WO PCT/JP1992/000548 patent/WO1992020683A1/ja not_active Ceased
-
1998
- 1998-08-20 GR GR980401862T patent/GR3027686T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3027686T3 (en) | 1998-11-30 |
| EP0590150B1 (en) | 1998-07-08 |
| CA2109117A1 (en) | 1992-11-16 |
| WO1992020683A1 (fr) | 1992-11-26 |
| EP0590150A1 (en) | 1994-04-06 |
| RU2057132C1 (ru) | 1996-03-27 |
| ES2118814T3 (es) | 1998-10-01 |
| AU1666392A (en) | 1992-12-30 |
| EP0590150A4 (en) | 1994-06-29 |
| DE69226187D1 (de) | 1998-08-13 |
| US5403931A (en) | 1995-04-04 |
| ATE168114T1 (de) | 1998-07-15 |
| DE69226187T2 (de) | 1998-10-22 |
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