ES2118814T3 - L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano. - Google Patents

L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano.

Info

Publication number
ES2118814T3
ES2118814T3 ES92909279T ES92909279T ES2118814T3 ES 2118814 T3 ES2118814 T3 ES 2118814T3 ES 92909279 T ES92909279 T ES 92909279T ES 92909279 T ES92909279 T ES 92909279T ES 2118814 T3 ES2118814 T3 ES 2118814T3
Authority
ES
Spain
Prior art keywords
azaspiro
oxa
tartrate
methylene
dimetil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92909279T
Other languages
English (en)
Inventor
Shin-Ichi Tsukamoto
Takeru Kohinata
Mitsuo Fujii
Sakiko Tomizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2118814T3 publication Critical patent/ES2118814T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L-TARTRATO DE (-)-(S)-2,8-DIMETIL-3-METILEN-1-OXA-8-AZASPIRO[4,5]DECANO CON UNA ESTABILIDAD DE CONSERVACION SUPERIOR A LA DE OTRAS SALES Y QUE SE PUEDE APLICAR COMO MEDICINA.
ES92909279T 1991-05-15 1992-04-27 L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano. Expired - Lifetime ES2118814T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13961991 1991-05-15

Publications (1)

Publication Number Publication Date
ES2118814T3 true ES2118814T3 (es) 1998-10-01

Family

ID=15249510

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92909279T Expired - Lifetime ES2118814T3 (es) 1991-05-15 1992-04-27 L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano.

Country Status (11)

Country Link
US (1) US5403931A (es)
EP (1) EP0590150B1 (es)
AT (1) ATE168114T1 (es)
AU (1) AU1666392A (es)
CA (1) CA2109117A1 (es)
DE (1) DE69226187T2 (es)
DK (1) DK0590150T3 (es)
ES (1) ES2118814T3 (es)
GR (1) GR3027686T3 (es)
RU (1) RU2057132C1 (es)
WO (1) WO1992020683A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ273129A (en) * 1993-08-19 1996-08-27 Merck & Co Inc 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b benzoic acid salt hemihydrate; pesticidal compositions
JP2002509888A (ja) * 1998-03-27 2002-04-02 オレゴン ヘルス サイエンシーズ ユニバーシティー 腫瘍および他の過増殖性疾患の治療におけるビタミンｄおよびその類似体
JP2003063964A (ja) * 2001-08-28 2003-03-05 Senju Pharmaceut Co Ltd ドライアイまたはドライアイを伴なう疾病の予防治療剤
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
KR20080031430A (ko) * 2005-07-26 2008-04-08 센주 세이야꾸 가부시키가이샤 경피적으로 흡수가능한 안과용 제제
EP2275096A3 (en) 2005-08-26 2011-07-13 Braincells, Inc. Neurogenesis via modulation of the muscarinic receptors
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010084499A2 (en) * 2009-01-26 2010-07-29 Israel Institute For Biological Research Bicyclic heterocyclic spiro compounds
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122353T1 (de) * 1987-10-05 1995-05-15 Yamanouchi Pharma Co Ltd Heterozyklische spiroverbindungen und ihre herstellung.
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives

Also Published As

Publication number Publication date
EP0590150B1 (en) 1998-07-08
EP0590150A4 (en) 1994-06-29
WO1992020683A1 (fr) 1992-11-26
DK0590150T3 (da) 1999-04-19
RU2057132C1 (ru) 1996-03-27
AU1666392A (en) 1992-12-30
DE69226187D1 (de) 1998-08-13
CA2109117A1 (en) 1992-11-16
EP0590150A1 (en) 1994-04-06
ATE168114T1 (de) 1998-07-15
GR3027686T3 (en) 1998-11-30
DE69226187T2 (de) 1998-10-22
US5403931A (en) 1995-04-04

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