ATE168114T1 - (-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8- azaspiro(4,5)decan l-tartrat - Google Patents

(-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8- azaspiro(4,5)decan l-tartrat

Info

Publication number
ATE168114T1
ATE168114T1 AT92909279T AT92909279T ATE168114T1 AT E168114 T1 ATE168114 T1 AT E168114T1 AT 92909279 T AT92909279 T AT 92909279T AT 92909279 T AT92909279 T AT 92909279T AT E168114 T1 ATE168114 T1 AT E168114T1
Authority
AT
Austria
Prior art keywords
azaspiro
oxa
tartrate
methylene
dimethyl
Prior art date
Application number
AT92909279T
Other languages
English (en)
Inventor
Shin-Ichi Tsukamoto
Takeru Kohinata
Mitsuo Fujii
Sakiko Tomizawa
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE168114T1 publication Critical patent/ATE168114T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT92909279T 1991-05-15 1992-04-27 (-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8- azaspiro(4,5)decan l-tartrat ATE168114T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13961991 1991-05-15

Publications (1)

Publication Number Publication Date
ATE168114T1 true ATE168114T1 (de) 1998-07-15

Family

ID=15249510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92909279T ATE168114T1 (de) 1991-05-15 1992-04-27 (-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8- azaspiro(4,5)decan l-tartrat

Country Status (11)

Country Link
US (1) US5403931A (de)
EP (1) EP0590150B1 (de)
AT (1) ATE168114T1 (de)
AU (1) AU1666392A (de)
CA (1) CA2109117A1 (de)
DE (1) DE69226187T2 (de)
DK (1) DK0590150T3 (de)
ES (1) ES2118814T3 (de)
GR (1) GR3027686T3 (de)
RU (1) RU2057132C1 (de)
WO (1) WO1992020683A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2168843C (en) * 1993-08-19 2004-10-19 Raymond Cvetovich Thermodynamically stable crystal form of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b benzoic acid salt and processes for its preparation
ES2368824T3 (es) * 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
JP2003063964A (ja) * 2001-08-28 2003-03-05 Senju Pharmaceut Co Ltd ドライアイまたはドライアイを伴なう疾病の予防治療剤
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
KR20080031430A (ko) * 2005-07-26 2008-04-08 센주 세이야꾸 가부시키가이샤 경피적으로 흡수가능한 안과용 제제
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
EP2275095A3 (de) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese durch modulation des Muscarinrezeptors
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
KR20150116466A (ko) * 2009-01-26 2015-10-15 이스라엘 인스티튜트 포 바이올로지컬 리서치 이환형 헤테로사이클릭 스피로 화합물
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3853758T2 (de) * 1987-10-05 1995-09-07 Yamanouchi Pharma Co Ltd Heterozyklische Spiroverbindungen und ihre Herstellung.
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives

Also Published As

Publication number Publication date
ES2118814T3 (es) 1998-10-01
CA2109117A1 (en) 1992-11-16
DE69226187T2 (de) 1998-10-22
EP0590150B1 (de) 1998-07-08
US5403931A (en) 1995-04-04
EP0590150A1 (de) 1994-04-06
DE69226187D1 (de) 1998-08-13
WO1992020683A1 (fr) 1992-11-26
GR3027686T3 (en) 1998-11-30
AU1666392A (en) 1992-12-30
EP0590150A4 (en) 1994-06-29
RU2057132C1 (ru) 1996-03-27
DK0590150T3 (da) 1999-04-19

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee