GR3027686T3 - (-)-(s)-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro 4,5]decane l-tartrate - Google Patents
(-)-(s)-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro 4,5]decane l-tartrateInfo
- Publication number
- GR3027686T3 GR3027686T3 GR980401862T GR980401862T GR3027686T3 GR 3027686 T3 GR3027686 T3 GR 3027686T3 GR 980401862 T GR980401862 T GR 980401862T GR 980401862 T GR980401862 T GR 980401862T GR 3027686 T3 GR3027686 T3 GR 3027686T3
- Authority
- GR
- Greece
- Prior art keywords
- azaspiro
- oxa
- decane
- tartrate
- methylene
- Prior art date
Links
- DIOQZVSQGTUSAI-UHFFFAOYSA-N decane Chemical compound CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 title 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 title 1
- RMKUOCBJRZODFU-LDGFUSNJSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;(2s)-2,8-dimethyl-3-methylidene-1-oxa-8-azaspiro[4.5]decane Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.C1C(=C)[C@H](C)OC21CCN(C)CC2 RMKUOCBJRZODFU-LDGFUSNJSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13961991 | 1991-05-15 | ||
| PCT/JP1992/000548 WO1992020683A1 (fr) | 1991-05-15 | 1992-04-27 | L-tartrate de (-)-(s)-2,8-dimethyl-3-methylen-1-oxa-8-azaspiro[4,5]decane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3027686T3 true GR3027686T3 (en) | 1998-11-30 |
Family
ID=15249510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR980401862T GR3027686T3 (en) | 1991-05-15 | 1998-08-20 | (-)-(s)-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro 4,5]decane l-tartrate |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5403931A (el) |
| EP (1) | EP0590150B1 (el) |
| AT (1) | ATE168114T1 (el) |
| AU (1) | AU1666392A (el) |
| CA (1) | CA2109117A1 (el) |
| DE (1) | DE69226187T2 (el) |
| DK (1) | DK0590150T3 (el) |
| ES (1) | ES2118814T3 (el) |
| GR (1) | GR3027686T3 (el) |
| RU (1) | RU2057132C1 (el) |
| WO (1) | WO1992020683A1 (el) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217769B (hu) * | 1993-08-19 | 2000-04-28 | Merck & Co. Inc. | 4"-Dezoxi-4"-epi-metil-amino-avermektin-B1a/B1b benzoesavas sójának termodinamikailag stabil kristályformája és eljárás annak előállítására, hatóanyagként ezt tartalmazó kompozíció és eljárás rovarok lekűzdésére |
| WO1999049870A1 (en) * | 1998-03-27 | 1999-10-07 | Oregon Health Sciences University | Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders |
| JP2003063964A (ja) * | 2001-08-28 | 2003-03-05 | Senju Pharmaceut Co Ltd | ドライアイまたはドライアイを伴なう疾病の予防治療剤 |
| US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| WO2007013661A1 (ja) * | 2005-07-26 | 2007-02-01 | Senju Pharmaceutical Co., Ltd. | 眼科用経皮吸収型製剤 |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP1928437A2 (en) * | 2005-08-26 | 2008-06-11 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| EP2068872A1 (en) | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| AU2010207486B2 (en) * | 2009-01-26 | 2013-03-07 | Israel Institute For Biological Research | Bicyclic heterocyclic spiro compounds |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3853758T2 (de) * | 1987-10-05 | 1995-09-07 | Yamanouchi Pharma Co Ltd | Heterozyklische Spiroverbindungen und ihre Herstellung. |
| US5075317A (en) * | 1989-06-21 | 1991-12-24 | Fisons Corporation | Spirofurane derivatives |
-
1992
- 1992-04-27 WO PCT/JP1992/000548 patent/WO1992020683A1/ja not_active Ceased
- 1992-04-27 AU AU16663/92A patent/AU1666392A/en not_active Abandoned
- 1992-04-27 DK DK92909279T patent/DK0590150T3/da active
- 1992-04-27 ES ES92909279T patent/ES2118814T3/es not_active Expired - Lifetime
- 1992-04-27 DE DE69226187T patent/DE69226187T2/de not_active Expired - Fee Related
- 1992-04-27 EP EP92909279A patent/EP0590150B1/en not_active Expired - Lifetime
- 1992-04-27 RU RU9293058306A patent/RU2057132C1/ru active
- 1992-04-27 CA CA002109117A patent/CA2109117A1/en not_active Abandoned
- 1992-04-27 AT AT92909279T patent/ATE168114T1/de not_active IP Right Cessation
- 1992-04-27 US US08/146,133 patent/US5403931A/en not_active Expired - Fee Related
-
1998
- 1998-08-20 GR GR980401862T patent/GR3027686T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2109117A1 (en) | 1992-11-16 |
| DE69226187D1 (de) | 1998-08-13 |
| EP0590150A4 (en) | 1994-06-29 |
| EP0590150B1 (en) | 1998-07-08 |
| DK0590150T3 (da) | 1999-04-19 |
| DE69226187T2 (de) | 1998-10-22 |
| AU1666392A (en) | 1992-12-30 |
| ATE168114T1 (de) | 1998-07-15 |
| RU2057132C1 (ru) | 1996-03-27 |
| US5403931A (en) | 1995-04-04 |
| EP0590150A1 (en) | 1994-04-06 |
| ES2118814T3 (es) | 1998-10-01 |
| WO1992020683A1 (fr) | 1992-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GR3027686T3 (en) | (-)-(s)-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro 4,5]decane l-tartrate | |
| USD335084S (en) | Bottle | |
| PT91553A (pt) | Processo de preparacao de uma composicao contendo morfina | |
| IL84425A (en) | (s) - (+) -ibuprofen-containing pharmaceutical compositions | |
| SG67901A1 (en) | Preparation and use of salts of the pure enantiomers of alpha-lipoic acid | |
| GR3001185T3 (en) | Stable solid pharmaceutical composition containing ibuprofen and codeine | |
| IE900709L (en) | Pharmaceutical composition which contains a pharmaceutically¹suitable carrier and the compound having the structure¹(7ó,17ó)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-¹3-one | |
| AU5629690A (en) | Carboplatin composition | |
| RU93058306A (ru) | Моногидрат l-тартрата(-)-(s)-2,8-диметил-3-метилен-1-окса-8-азаспиро-(4,5)-декана | |
| USD302206S (en) | Cap for a syringe or similar article | |
| IL109139A0 (en) | Diamine salts of clavulanic acid, their preparation and pharmaceutical compositions containing them | |
| GR3033728T3 (en) | Tablets containing thioctic acid with a specified size. | |
| EP0430552A3 (en) | Treatment of pulmonary dysfunction with 15-keto-prostaglandin compounds | |
| USD303427S (en) | Combined dental syringe and cap | |
| CA2056799A1 (en) | 1,4-dihydropyridine derivatives and methods of producing the same | |
| IL98200A0 (en) | Pharmaceutical composition containing a derivative of substituted-l-valyl-l-prolinamide | |
| USD310351S (en) | Character indicia encoding desk for mail | |
| PL298827A1 (en) | Novel enantiomers derivatives of (s)-2-amino(3,4-dichlorobenzyl) propanol-1 | |
| EP0339386A3 (en) | Bipolar transistor structure for use as a photodetector | |
| JPS57175194A (en) | 10b-carboxy-aminoboran and physiologically available salts of same, manufacture and use as neutron catching treatment medicine | |
| IL72955A0 (en) | Racemic cis and trans hydroxy-iminooctahydroindolo(2,3-a)-quinolizine derivatives,the corresponding optically active derivatives and acid addition salts,their preparation and pharmaceutical compositions containing them | |
| AU100912S (en) | A rung | |
| IT212028Z2 (it) | Tavolo con schema per gioco di societa'. |