DK0590415T3 - 1,2,4-Oxadiazolderivater til bekæmpelse af endoparasitter - Google Patents

1,2,4-Oxadiazolderivater til bekæmpelse af endoparasitter

Info

Publication number: DK0590415T3
Authority: DK; Denmark
Prior art keywords: stands; alkyl; hydrogen; endoparasites; alkylcarbonyl
Prior art date: 1992-09-28

Application number

DK93114857.1T

Other languages

English (en)

Inventor

Peter Dr Jeschke

Werner Dr Lindner

Achim Dr Harder

Norbert Dr Mencke

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-28

Filing date

1993-09-15

Publication date

1997-12-22

1993-09-15 Application filed by Bayer Ag filed Critical Bayer Ag

1997-12-22 Application granted granted Critical

1997-12-22 Publication of DK0590415T3 publication Critical patent/DK0590415T3/da

Links

150000005071 1,2,4-oxadiazoles Chemical class 0.000 title abstract 2
244000079386 endoparasite Species 0.000 title abstract 2
-1 cyano, nitro, isothiocyanato, amino Chemical group 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 2
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
125000004663 dialkyl amino group Chemical group 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
125000005110 aryl thio group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000006310 cycloalkyl amino group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000004438 haloalkoxy group Chemical group 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
125000004692 haloalkylcarbonyl group Chemical group 0.000 abstract 1
125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 1
125000004995 haloalkylthio group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000005113 hydroxyalkoxy group Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000003107 substituted aryl group Chemical group 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Dentistry (AREA)
Tropical Medicine & Parasitology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Pest Control & Pesticides (AREA)
Environmental Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Agronomy & Crop Science (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK93114857.1T 1992-09-28 1993-09-15 1,2,4-Oxadiazolderivater til bekæmpelse af endoparasitter DK0590415T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4232418A DE4232418A1 (de)	1992-09-28	1992-09-28	Verwendung von substituierten 1,2,4-Oxadiazolderivaten zur Bekämpfung von Endoparasiten, neue substituierte 1,2,4-Oxadiazolderivate und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number	Publication Date
DK0590415T3 true DK0590415T3 (da)	1997-12-22

Family

ID=6468996

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93114857.1T DK0590415T3 (da)	1992-09-28	1993-09-15	1,2,4-Oxadiazolderivater til bekæmpelse af endoparasitter

Country Status (13)

Country	Link
US (1)	US5428047A (da)
EP (1)	EP0590415B1 (da)
JP (1)	JP3463945B2 (da)
KR (1)	KR100295272B1 (da)
AT (1)	ATE154015T1 (da)
AU (1)	AU662833B2 (da)
CA (1)	CA2106897C (da)
DE (2)	DE4232418A1 (da)
DK (1)	DK0590415T3 (da)
ES (1)	ES2104014T3 (da)
GR (1)	GR3024272T3 (da)
TW (1)	TW308590B (da)
ZA (1)	ZA937139B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4401108A1 (de) *	1994-01-17	1995-07-20	Bayer Ag	1,2,4-Oxadiazol-Derivate
KR101674463B1 (ko) *	2013-04-03	2016-11-10	서울대학교산학협력단	Ｓｔａｔ３ 저해활성을 갖는 화합물 및 이의 용도
AR111295A1 (es)	2017-03-20	2019-06-26	Forma Therapeutics Inc	Composiciones de pirrolopirrol como activadores de piruvato quinasa (pkr)
WO2020061255A1 (en)	2018-09-19	2020-03-26	Forma Therapeutics, Inc.	Activating pyruvate kinase r
US20200129485A1 (en)	2018-09-19	2020-04-30	Forma Therapeutics, Inc.	Treating sickle cell disease with a pyruvate kinase r activating compound
MX2022003025A (es)	2019-09-19	2022-04-07	Forma Therapeutics Inc	Activacion de la piruvato cinasa r.
US12128035B2 (en)	2021-03-19	2024-10-29	Novo Nordisk Health Care Ag	Activating pyruvate kinase R

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1620574A1 (de) *	1966-11-15	1970-04-30	Troponwerke Dinklage & Co	Neue substituierte 1,2,4-Oxadiazolverbindungen und Verfahren zu ihrer Herstellung
GB1228142A (da) *	1967-03-31	1971-04-15
US3879407A (en) *	1973-02-09	1975-04-22	Johnson & Son Inc S C	1,2,4-Oxadiazole and thiadiazole esters and compositions containing same
US4294843A (en) *	1978-07-13	1981-10-13	Burroughs Wellcome Co.	Anti-protozoal oxadiazole derivatives
EP0007529B1 (en) *	1978-07-13	1983-07-20	The Wellcome Foundation Limited	Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them
DE2842284A1 (de) *	1978-09-28	1980-04-17	Bayer Ag	N-diazolylalkyl-halogenacetanilide, verfahren zu ihrer herstellung sowie ihre verwendung als herbizide
JPS57175177A (en) *	1981-04-21	1982-10-28	Mitsui Toatsu Chem Inc	3-ethyloxadiazole derivative, its preparation, and herbicide
JPS58183688A (ja) *	1982-04-20	1983-10-26	Nippon Tokushu Noyaku Seizo Kk	オキサジアゾ−ル誘導体、その製法及び除草剤
US4812161A (en) *	1984-08-08	1989-03-14	Nippon Soda Co., Ltd.	Thia (oxa) diazole derivatives
JPS62267274A (ja) *	1986-05-16	1987-11-19	Aguro Kanesho Kk	１，２，４−オキサジアゾ−ル誘導体
JPS63264584A (ja) *	1987-04-20	1988-11-01	Aguro Kanesho Kk	除草剤組成物
GB8712396D0 (en) *	1987-05-27	1987-07-01	May & Baker Ltd	Composition of matter
JPH01249768A (ja) *	1988-03-30	1989-10-05	Nippon Tokushu Noyaku Seizo Kk	Ｎ−置換フエニル−ヘテロ環式化合物及び除草剤
DE4041474A1 (de) *	1990-12-22	1992-06-25	Bayer Ag	Verwendung von substituierten 1,2,4-oxadiazolderivaten zur bekaempfung von endoparasiten, neue substituierte 1,2,4-oxadiazolderivate und verfahren zu ihrer herstellung

1992
- 1992-09-28 DE DE4232418A patent/DE4232418A1/de not_active Withdrawn
1993
- 1993-08-26 AU AU44929/93A patent/AU662833B2/en not_active Ceased
- 1993-08-31 TW TW082107047A patent/TW308590B/zh active
- 1993-09-15 DK DK93114857.1T patent/DK0590415T3/da active
- 1993-09-15 DE DE59306648T patent/DE59306648D1/de not_active Expired - Lifetime
- 1993-09-15 EP EP93114857A patent/EP0590415B1/de not_active Expired - Lifetime
- 1993-09-15 ES ES93114857T patent/ES2104014T3/es not_active Expired - Lifetime
- 1993-09-15 AT AT93114857T patent/ATE154015T1/de not_active IP Right Cessation
- 1993-09-21 US US08/124,909 patent/US5428047A/en not_active Expired - Lifetime
- 1993-09-22 JP JP25753493A patent/JP3463945B2/ja not_active Expired - Fee Related
- 1993-09-24 CA CA002106897A patent/CA2106897C/en not_active Expired - Fee Related
- 1993-09-24 KR KR1019930019693A patent/KR100295272B1/ko not_active Expired - Fee Related
- 1993-09-27 ZA ZA937139A patent/ZA937139B/xx unknown
1997
- 1997-07-30 GR GR970401921T patent/GR3024272T3/el unknown

Also Published As

Publication number	Publication date
AU662833B2 (en)	1995-09-14
KR100295272B1 (ko)	2001-09-17
TW308590B (da)	1997-06-21
DE59306648D1 (de)	1997-07-10
CA2106897C (en)	2005-01-04
AU4492993A (en)	1994-04-14
ATE154015T1 (de)	1997-06-15
GR3024272T3 (en)	1997-10-31
JP3463945B2 (ja)	2003-11-05
CA2106897A1 (en)	1994-03-29
ZA937139B (en)	1994-03-29
ES2104014T3 (es)	1997-10-01
US5428047A (en)	1995-06-27
EP0590415B1 (de)	1997-06-04
JPH06192243A (ja)	1994-07-12
EP0590415A3 (en)	1994-06-01
EP0590415A2 (de)	1994-04-06
DE4232418A1 (de)	1994-03-31
KR940006589A (ko)	1994-04-25

Publication	Publication Date	Title
SE8503888D0 (sv)	1985-08-20	Heterocykliska derivat
ATE194340T1 (de)	2000-07-15	Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
ATE94162T1 (de)	1993-09-15	Dihydropyridin-derivate, ihre herstellung und ihre verwendung.
DK537289D0 (da)	1989-10-27	4h-1-benzopyran-4-on-derivater, deres fremstilling og anvendelse
ATE69221T1 (de)	1991-11-15	Verfahren zur synthese von 3-thia-4chinolonderivaten und zwischenprodukte dafuer und ihre verwendung als arzneimittel.
ATE302778T1 (de)	2005-09-15	N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE74132T1 (de)	1992-04-15	Imid-derivate, ihre herstellung und ihre verwendung.
DK0579124T3 (da)	1996-11-18	Substituerede oximethere, fremgangsmåde til deres fremstilling og deres anvendelse til bekæmpelse af skadelige organismer og svampe
ATE163921T1 (de)	1998-03-15	Azoxycyanbenzol-derivate
DE59306648D1 (de)	1997-07-10	1,2,4-Oxadiazolderivate zur Bekämpfung von Endoparasiten
NZ228065A (en)	1990-09-26	1,2,4-triazinediones and parasiticidal compositions; processes for preparation
ATE92489T1 (de)	1993-08-15	Imid-derivate, ihre herstellung und verwendung.
ATE33833T1 (de)	1988-05-15	Substituierte 4,5-dimethoxypyridazone, verfahren zu ihrer herstellung, diese enthaltende herbizide und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses.
DK0586405T3 (da)	1997-12-01	Hidtil ukendte 2-H-benzo(b)pyranderivater substitueret i 4-stillingen med aryl eller N-heteroaryl, fremgangsmåder til fremstilling deraf og præparater indeholdende forbindelserne
DE3887102D1 (de)	1994-02-24	Substituierte Derivate von 20,21-Dinoreburnamenin, Verfahren zur Herstellung und so hergestellte Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammenstellungen.
DE3853958D1 (de)	1995-07-13	Substituierte Pyridin-Verbindungen, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.
DK0492249T3 (da)	1996-09-30	Anvendelse af substituerede 1,2,4-oxadiazolderivater til bekæmpelse af endoparasitter, nye substituerede 1,2,4-oxadiazolderivater samt fremgangsmåder til deres fremstilling
HUT45373A (en)	1988-07-28	Herbicides containing as active substance derivatives of 1-carbamoil-2-pinasoline and process for production of the active substances
ATE92058T1 (de)	1993-08-15	Pyrimidin-derivate, 2-(4-(alpha-heteroaryl-alphaaryl-(alpha-alkyl)-methoxy)-butyl)-1-piperaziny > mit serotoninergischer wirkung.
DE59104473D1 (de)	1995-03-16	Arzneimittel welche substituierte 2-Cyclohexen-1yl-amin-Derivate enthalten und ihre Verwendung zur Bekämpfung von Krankheiten.
CA2050465A1 (en)	1992-03-04	Cyclohexenol derivatives
DE69319356D1 (de)	1998-08-06	Thiolderivate von Gallensäure
DK0653417T3 (da)	1998-03-30	P-Hydroxyanilinderivater, fremgangsmåde til deres fremstilling og deres anvendelse til bekæmpelse af skadelige svampe eller skadedyr
DE59609237D1 (de)	2002-06-27	Iminooxybenzylverbindungen und ihre verwendung zur bekämpfung von tierischen schädlingen und schadpilzen
ATE50244T1 (de)	1990-02-15	Aminosaeureester.