DK0618807T3 - Stabiliseret farmaceutisk formulering omfattende human væksthormon og histidin - Google Patents

Stabiliseret farmaceutisk formulering omfattende human væksthormon og histidin

Info

Publication number
DK0618807T3
DK0618807T3 DK93902089T DK93902089T DK0618807T3 DK 0618807 T3 DK0618807 T3 DK 0618807T3 DK 93902089 T DK93902089 T DK 93902089T DK 93902089 T DK93902089 T DK 93902089T DK 0618807 T3 DK0618807 T3 DK 0618807T3
Authority
DK
Denmark
Prior art keywords
histidine
growth hormone
pharmaceutical formulation
human growth
stabilized pharmaceutical
Prior art date
Application number
DK93902089T
Other languages
Danish (da)
English (en)
Inventor
Hans Holmegaard Soerensen
Lars Skriver
Annie Rassing Hoelgaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK204691A external-priority patent/DK204691D0/da
Priority claimed from DK136492A external-priority patent/DK136492D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0618807T3 publication Critical patent/DK0618807T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93902089T 1991-12-20 1992-12-16 Stabiliseret farmaceutisk formulering omfattende human væksthormon og histidin DK0618807T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK204691A DK204691D0 (da) 1991-12-20 1991-12-20 Hidtil ukendt farmaceutisk praeparat
DK136492A DK136492D0 (da) 1992-11-10 1992-11-10 A pharmaceutical formulation
PCT/DK1992/000379 WO1993012812A1 (en) 1991-12-20 1992-12-16 A stabilized pharmaceutical formulation comprising growth hormone and histidine

Publications (1)

Publication Number Publication Date
DK0618807T3 true DK0618807T3 (da) 2003-03-03

Family

ID=26065653

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93902089T DK0618807T3 (da) 1991-12-20 1992-12-16 Stabiliseret farmaceutisk formulering omfattende human væksthormon og histidin

Country Status (24)

Country Link
EP (2) EP0618807B1 (de)
JP (2) JP2950617B2 (de)
KR (1) KR100266502B1 (de)
AT (2) ATE368472T1 (de)
AU (1) AU667503B2 (de)
BG (1) BG63075B1 (de)
CA (1) CA2125855C (de)
CZ (1) CZ283361B6 (de)
DE (3) DE69233704T2 (de)
DK (1) DK0618807T3 (de)
ES (2) ES2185625T3 (de)
FI (1) FI115116B (de)
HU (1) HUT69402A (de)
IL (1) IL104152A (de)
MX (1) MX9207374A (de)
NL (1) NL300126I1 (de)
NO (1) NO942300L (de)
NZ (1) NZ246556A (de)
PT (1) PT618807E (de)
RO (1) RO111990B1 (de)
RU (1) RU2122426C1 (de)
SK (1) SK279641B6 (de)
UA (1) UA41502C2 (de)
WO (1) WO1993012812A1 (de)

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IL115592A (en) * 1994-10-13 2000-07-26 Novo Nordisk As Stabilized pharmaceutical formulation comprising a growth hormone and leucine
US5631225A (en) * 1994-10-13 1997-05-20 Novo Nordisk A/S Pharmaceutical formulation
US5654278A (en) * 1994-10-13 1997-08-05 Novo Nordisk A/S Composition and method comprising growth hormone and leucine
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KR20030023878A (ko) 2000-06-26 2003-03-20 몬산토 테크놀로지 엘엘씨 소마토트로핀의 지속적인 방출을 위한 계면활성제 함유비수성 제제들
US6664234B1 (en) 2000-06-30 2003-12-16 Monsanto Technology Llc Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin
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US8632778B2 (en) 2000-08-11 2014-01-21 Chugai Seiyaku Kabushiki Kaisha Stabilized anti-interleukin-6 antibody-containing preparations
EP1387616B1 (de) 2001-05-18 2007-05-16 Danisco A/S Verfahren zur herstellung von teig mit einem enzym
DK1581251T3 (da) 2002-12-31 2016-06-27 Althea Tech Inc Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf
NZ554885A (en) * 2002-12-31 2009-07-31 Altus Pharmaceuticals Inc Complexes of hgh crystals and protamine polymers
DE602004030000D1 (de) 2003-01-17 2010-12-23 Danisco Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
KR101159559B1 (ko) 2003-08-05 2012-06-26 노보 노르디스크 에이/에스 신규의 인슐린 유도체
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US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
US9175061B2 (en) 2006-07-07 2015-11-03 Novo Nordisk Health Care Ag Protein conjugates and methods for their preparation
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JP6049625B2 (ja) 2010-10-27 2016-12-21 ノヴォ ノルディスク アー／エス 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療
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AU2013273138B2 (en) 2012-06-05 2017-06-15 Neuroderm Ltd Compositions comprising apomorphine and organic acids and uses thereof
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
WO2014177623A1 (en) 2013-04-30 2014-11-06 Novo Nordisk A/S Novel administration regime
US11559580B1 (en) * 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
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ES3049426T3 (en) * 2018-05-25 2025-12-16 Dr Reddys Laboratories Ltd Stable fusion protein formulation
KR20210024082A (ko) * 2018-06-25 2021-03-04 제이씨알 파마 가부시키가이샤 단백질 함유 수성 액제
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Also Published As

Publication number Publication date
UA41502C2 (uk) 2001-09-17
IL104152A0 (en) 1993-05-13
DE69233704D1 (de) 2007-09-13
EP0618807A1 (de) 1994-10-12
ATE368472T1 (de) 2007-08-15
AU3344693A (en) 1993-07-28
ES2185625T3 (es) 2003-05-01
HU9401832D0 (en) 1994-09-28
CZ283361B6 (cs) 1998-03-18
RU2122426C1 (ru) 1998-11-27
RO111990B1 (ro) 1997-04-30
EP0618807B1 (de) 2002-11-13
SK279641B6 (sk) 1999-01-11
NO942300D0 (no) 1994-06-17
DE69232847D1 (de) 2002-12-19
DE10399015I1 (de) 2012-05-03
SK75494A3 (en) 1995-03-08
HUT69402A (en) 1995-09-28
KR100266502B1 (ko) 2000-09-15
AU667503B2 (en) 1996-03-28
DE69232847T2 (de) 2003-09-11
DE69233704T2 (de) 2008-05-21
BG63075B1 (bg) 2001-03-30
EP1197222A3 (de) 2004-02-04
FI942906A0 (fi) 1994-06-17
CZ150794A3 (en) 1995-01-18
JPH11315031A (ja) 1999-11-16
NL300126I1 (nl) 2003-07-01
NO942300L (no) 1994-08-19
CA2125855A1 (en) 1993-07-08
WO1993012812A1 (en) 1993-07-08
FI115116B (fi) 2005-03-15
BG98806A (bg) 1995-02-28
CA2125855C (en) 2008-05-13
DE10399015I2 (de) 2008-08-07
PT618807E (pt) 2003-03-31
MX9207374A (es) 1993-07-01
ATE227583T1 (de) 2002-11-15
FI942906L (fi) 1994-06-17
JPH07502516A (ja) 1995-03-16
EP1197222B1 (de) 2007-08-01
NZ246556A (en) 1996-03-26
EP1197222A2 (de) 2002-04-17
IL104152A (en) 1998-06-15
JP2950617B2 (ja) 1999-09-20
RU94045932A (ru) 1997-04-20
ES2291264T3 (es) 2008-03-01

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