DK0633887T3 - Antivirale calanolidforbindelser, præparater og anvendelser deraf - Google Patents

Antivirale calanolidforbindelser, præparater og anvendelser deraf

Info

Publication number
DK0633887T3
DK0633887T3 DK93908587T DK93908587T DK0633887T3 DK 0633887 T3 DK0633887 T3 DK 0633887T3 DK 93908587 T DK93908587 T DK 93908587T DK 93908587 T DK93908587 T DK 93908587T DK 0633887 T3 DK0633887 T3 DK 0633887T3
Authority
DK
Denmark
Prior art keywords
compounds
antiviral
calanolid
preparations
derivatives
Prior art date
Application number
DK93908587T
Other languages
English (en)
Inventor
Michael R Boyd
John H Ii Cardellina
Kirk R Gustafson
James B Mcmahon
Richard W Fuller
Gordon M Cragg
Yoel Kashman
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK0633887T3 publication Critical patent/DK0633887T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK93908587T 1992-03-31 1993-03-24 Antivirale calanolidforbindelser, præparater og anvendelser deraf DK0633887T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86124992A 1992-03-31 1992-03-31
PCT/US1993/002810 WO1993020082A1 (en) 1992-03-31 1993-03-24 Calanolide antiviral compounds, compositions and uses thereof

Publications (1)

Publication Number Publication Date
DK0633887T3 true DK0633887T3 (da) 1999-11-29

Family

ID=25335281

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908587T DK0633887T3 (da) 1992-03-31 1993-03-24 Antivirale calanolidforbindelser, præparater og anvendelser deraf

Country Status (10)

Country Link
EP (1) EP0633887B1 (da)
JP (1) JP3103114B2 (da)
AT (1) ATE180259T1 (da)
AU (1) AU671827B2 (da)
CA (1) CA2133080C (da)
DE (1) DE69325020T2 (da)
DK (1) DK0633887T3 (da)
ES (1) ES2134259T3 (da)
GR (1) GR3030852T3 (da)
WO (1) WO1993020082A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0674643A1 (en) * 1992-12-23 1995-10-04 Smithkline Beecham Corporation Coumarin derivatives as retroviral inhibitors
US5489697A (en) 1994-08-03 1996-02-06 Medichem Research, Inc. Method for the preparation of (+)-calanolide A and intermediates thereof
US5892060A (en) * 1994-08-03 1999-04-06 Sarawak Medichem Pharmaceuticals, Inc. Method for the preparation of (+)-calanolide a and analogues thereof
US5977385A (en) * 1994-08-03 1999-11-02 Sarawak Medichem Pharmaceuticals Method for the preparation of (+)-calanolide A and analogues thereof
US6043271A (en) * 1994-08-03 2000-03-28 Sarawak Medichem Pharmaceuticals, Inc. Method for the preparation of (±)-calanolide A and intermediates thereof
US6277879B1 (en) 1994-08-03 2001-08-21 Sarawak Medichem Pharmaceuticals, Inc. Calanolide analogues and methods of their use
US5608085A (en) * 1995-02-27 1997-03-04 The University Of Tennessee Research Corporation Synthesis of optically active calanolides A and B and enantiomers and related compounds
US6160131A (en) * 1997-12-19 2000-12-12 Sarawak Medichem Pharmaceuticals, Inc. Scalable method for the isolation of anti-HIV agents from the tropical plant calophyllum
EA200100347A1 (ru) * 1998-10-15 2001-10-22 Саравак Медичем Фармасьютикалс, Инк. Метод и композиция для лечения и профилактики туберкулеза
AU4491800A (en) 1999-04-26 2000-11-10 Sarawak Medichem Pharmaceuticals, Inc. Methods for preparing antiviral calanolide compounds
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211944A (en) * 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same

Also Published As

Publication number Publication date
JPH08502948A (ja) 1996-04-02
ES2134259T3 (es) 1999-10-01
DE69325020D1 (de) 1999-06-24
WO1993020082A1 (en) 1993-10-14
DE69325020T2 (de) 1999-11-18
GR3030852T3 (en) 1999-11-30
ATE180259T1 (de) 1999-06-15
AU671827B2 (en) 1996-09-12
EP0633887A1 (en) 1995-01-18
CA2133080C (en) 2006-06-06
AU3935593A (en) 1993-11-08
CA2133080A1 (en) 1993-10-14
JP3103114B2 (ja) 2000-10-23
EP0633887B1 (en) 1999-05-19

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