DK0637248T3 - Farmaceutisk sammensætning indeholdende et cyclosporinderivat - Google Patents

Farmaceutisk sammensætning indeholdende et cyclosporinderivat

Info

Publication number: DK0637248T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical composition; composition containing; cyclosporine derivative; composition; microemulstion
Prior art date: 1992-04-22

Application number

DK93911768T

Other languages

Danish (da)

English (en)

Inventor

Armin Meinzer

Friedrich Richter

Jacky Francis Vonderscher

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-22

Filing date

1993-04-20

Publication date

2002-10-28

1993-04-20 Application filed by Novartis Ag filed Critical Novartis Ag

2002-10-28 Application granted granted Critical

2002-10-28 Publication of DK0637248T3 publication Critical patent/DK0637248T3/da

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
206010048723 Multiple-drug resistance Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229960000074 biopharmaceutical Drugs 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
239000004530 micro-emulsion Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
239000008158 vegetable oil Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

DK93911768T 1992-04-22 1993-04-20 Farmaceutisk sammensætning indeholdende et cyclosporinderivat DK0637248T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929208712A GB9208712D0 (en)	1992-04-22	1992-04-22	Pharmaceutical compositions containing cyclosporin derivates
PCT/EP1993/000955 WO1993020833A1 (en)	1992-04-22	1993-04-20	Pharmaceutical composition containing cyclosporin derivative

Publications (1)

Publication Number	Publication Date
DK0637248T3 true DK0637248T3 (da)	2002-10-28

Family

ID=10714386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93911768T DK0637248T3 (da)	1992-04-22	1993-04-20	Farmaceutisk sammensætning indeholdende et cyclosporinderivat

Country Status (22)

Country	Link
EP (1)	EP0637248B1 (ja)
JP (1)	JP2818298B2 (ja)
KR (2)	KR950701227A (ja)
AT (1)	ATE219940T1 (ja)
AU (1)	AU672793B2 (ja)
CA (1)	CA2132740C (ja)
CY (1)	CY2399B1 (ja)
CZ (1)	CZ287359B6 (ja)
DE (1)	DE69332078T2 (ja)
DK (1)	DK0637248T3 (ja)
ES (1)	ES2179052T3 (ja)
FI (1)	FI111130B (ja)
GB (1)	GB9208712D0 (ja)
HU (1)	HU218279B (ja)
NO (1)	NO315075B1 (ja)
NZ (1)	NZ252681A (ja)
PT (1)	PT637248E (ja)
RU (1)	RU2126263C1 (ja)
SG (1)	SG50692A1 (ja)
SK (1)	SK282745B6 (ja)
UA (1)	UA34454C2 (ja)
WO (1)	WO1993020833A1 (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko)	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
HK1004520A1 (en) *	1992-05-13	1998-11-27	Novartis Ag	Ophthalmic compositions containing a cyclosporin
PT589843E (pt)	1992-09-25	2002-04-29	Novartis Ag	Composicoes farmaceuticas contendo ciclosporinas
CH686761A5 (de) *	1993-05-27	1996-06-28	Sandoz Ag	Galenische Formulierungen.
GB2278780B (en) *	1993-05-27	1998-10-14	Sandoz Ltd	Macrolide formulations
GB2315216B (en) *	1993-10-05	1998-10-14	Ciba Geigy Ag	Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
SK164796A3 (en)	1994-11-03	1997-06-04	Dresden Arzneimittel	Novel cyclosporine preparation forms for oral administration of and process for producing them
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5766629A (en)	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
DE19544507B4 (de)	1995-11-29	2007-11-15	Novartis Ag	Cyclosporin enthaltende Präparate
GB9601120D0 (en)	1996-01-19	1996-03-20	Sandoz Ltd	Organic compounds
HU223054B1 (hu) *	1997-03-25	2004-03-01	BIOGAL Gyógyszergyár Rt.	Tisztítási eljárás nagytisztaságú ciklosporin A előállítására
ATE265847T1 (de) *	1997-07-29	2004-05-15	Upjohn Co	Selbstemulgierbare formulierung enthaltend lipophile verbindungen
HU228923B1 (en) *	1997-07-29	2013-06-28	Upjohn Co	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation
US6187747B1 (en)	1997-09-08	2001-02-13	Panacea Biotech Limited	Pharmaceutical composition comprising cyclosporin
US6008191A (en) *	1997-09-08	1999-12-28	Panacea Biotec Limited	Pharmaceutical compositions containing cyclosporin
US6346511B1 (en)	1997-09-08	2002-02-12	Panacea Biotec Limited	Pharmaceutical composition comprising cyclosporin
KR20010041623A (ko) *	1998-03-05	2001-05-25	니뽄 신야쿠 가부시키가이샤	흡입 투여용 지방 유제
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
EA200301139A1 (ru)	2001-06-21	2004-12-30	Пфайзер Продактс Инк.	Самоэмульгирующиеся препараты ингибиторов белка-переносчика эфиров холестерина
IL160761A0 (en) *	2001-10-19	2004-08-31	Isotechnika Inc	Novel cyclosporin analog microemulsion preconcentrates
US6828301B2 (en)	2002-02-07	2004-12-07	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for hepatitis C viral protease inhibitors
RU2293763C2 (ru) *	2005-05-18	2007-02-20	Государственное учреждение Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова Российской академии медицинских наук (ГУ НИИВС им. И.И. Мечникова РАМН)	Способ получения акарицидно-моющего средства для борьбы с клещами
RU2294959C2 (ru) *	2005-05-18	2007-03-10	Общество с ограниченной ответственностью "Карат" (ООО "Карат")	Способ получения акарицидно-моющего средства для борьбы с клещами
RU2320365C2 (ru) *	2005-09-15	2008-03-27	Григорьев Лев Викторович	Фармацевтическая композиция
EP2204167A1 (en)	2009-01-05	2010-07-07	Azad Pharma AG	Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
MY154683A (en)	2009-07-07	2015-07-15	Boehringer Ingelheim Int	Pharmaceutical composition for a hepatitis c viral protease inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2907460A1 (de) *	1978-03-07	1979-09-13	Sandoz Ag	Neue resorbierbare galenische kompositionen
DE3884470T2 (de) *	1987-06-17	1994-03-10	Sandoz Ag	Cyclosporine und deren Benutzung als Arzneimittel.
PL155712B1 (en) *	1987-12-21	1991-12-31	Sandoz Ag	Method of obtaining novel crystalline form of cyclosporin
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물

1992
- 1992-04-22 GB GB929208712A patent/GB9208712D0/en active Pending
1993
- 1993-04-20 ES ES93911768T patent/ES2179052T3/es not_active Expired - Lifetime
- 1993-04-20 UA UA94105950A patent/UA34454C2/uk unknown
- 1993-04-20 CA CA002132740A patent/CA2132740C/en not_active Expired - Fee Related
- 1993-04-20 SG SG1996008843A patent/SG50692A1/en unknown
- 1993-04-20 JP JP5517998A patent/JP2818298B2/ja not_active Expired - Fee Related
- 1993-04-20 EP EP93911768A patent/EP0637248B1/en not_active Expired - Lifetime
- 1993-04-20 DK DK93911768T patent/DK0637248T3/da active
- 1993-04-20 PT PT93911768T patent/PT637248E/pt unknown
- 1993-04-20 SK SK1272-94A patent/SK282745B6/sk not_active IP Right Cessation
- 1993-04-20 AT AT93911768T patent/ATE219940T1/de not_active IP Right Cessation
- 1993-04-20 DE DE69332078T patent/DE69332078T2/de not_active Expired - Fee Related
- 1993-04-20 CZ CZ19942617A patent/CZ287359B6/cs not_active IP Right Cessation
- 1993-04-20 WO PCT/EP1993/000955 patent/WO1993020833A1/en not_active Ceased
- 1993-04-20 RU RU94046413A patent/RU2126263C1/ru active
- 1993-04-20 NZ NZ252681A patent/NZ252681A/en not_active IP Right Cessation
- 1993-04-20 AU AU42611/93A patent/AU672793B2/en not_active Ceased
- 1993-04-20 HU HU9403055A patent/HU218279B/hu not_active IP Right Cessation
1994
- 1994-10-20 KR KR1019940703729A patent/KR950701227A/ko not_active Withdrawn
- 1994-10-21 NO NO19943998A patent/NO315075B1/no not_active IP Right Cessation
- 1994-10-21 FI FI944978A patent/FI111130B/fi active
2000
- 2000-12-08 KR KR10-2000-7013956A patent/KR100414853B1/ko not_active Expired - Fee Related
2003
- 2003-12-31 CY CY0300096A patent/CY2399B1/xx unknown

Also Published As

Publication number	Publication date
KR100414853B1 (ja)	2004-01-13
CZ287359B6 (en)	2000-11-15
CY2399B1 (en)	2004-09-10
NO943998D0 (no)	1994-10-21
WO1993020833A1 (en)	1993-10-28
JPH07505872A (ja)	1995-06-29
DE69332078T2 (de)	2002-12-19
GB9208712D0 (en)	1992-06-10
UA34454C2 (uk)	2001-03-15
RU2126263C1 (ru)	1999-02-20
CA2132740C (en)	2008-01-15
AU672793B2 (en)	1996-10-17
KR950701227A (ko)	1995-03-23
FI944978A0 (fi)	1994-10-21
SG50692A1 (en)	1999-05-25
PT637248E (pt)	2002-11-29
ES2179052T3 (es)	2003-01-16
CZ261794A3 (en)	1995-02-15
HUT71580A (en)	1995-12-28
EP0637248B1 (en)	2002-07-03
HU9403055D0 (en)	1994-12-28
CA2132740A1 (en)	1993-10-28
NZ252681A (en)	1996-02-27
SK127294A3 (en)	1995-04-12
NO315075B1 (no)	2003-07-07
RU94046413A (ru)	1996-11-10
HU218279B (en)	2000-07-28
FI111130B (fi)	2003-06-13
FI944978L (fi)	1994-10-21
JP2818298B2 (ja)	1998-10-30
SK282745B6 (sk)	2002-12-03
EP0637248A1 (en)	1995-02-08
NO943998L (no)	1994-10-21
DE69332078D1 (de)	2002-08-08
AU4261193A (en)	1993-11-18
ATE219940T1 (de)	2002-07-15

Publication	Publication Date	Title
DK0637248T3 (da)	2002-10-28	Farmaceutisk sammensætning indeholdende et cyclosporinderivat
TNSN92004A1 (fr)	1993-06-08	Derive de la 5h-pyrrolo (3,4-b) pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent
MX9204379A (es)	1993-02-01	Microemulsiones de agua en aceite auto-emulsificables, estables, farmaceuticamente aceptables.
AU629669B2 (en)	1992-10-08	Diarylacetylenes, the preparations and use thereof
NO963242L (no)	1996-08-02	Lipofile bærerpreparater
UA40634C2 (uk)	2001-08-15	Мікрокапсула, яка містить суспензію твердої біологічно активної сполуки, і спосіб її одержання
ATE143830T1 (de)	1996-10-15	Mikrokapseln mit wänden aus primären alkoholfunktionen enthaltenden polysacchariden, und zusammensetzungen daraus
MXPA97007996A (es)	2004-03-15	Preparado para el transporte de sustancias activas a traves de barreras.
MX9204382A (es)	1993-08-01	Composiciones
KR950007857A (ko)	1995-04-15	경구투여용 라파마이신 제제
AU4693489A (en)	1990-06-21	Stable emulsion formulations of water-insoluable organic pesticides, their use and preparation
NO175826C (no)	1994-12-14	Mikrobiologisk fremgangsmåte ved fremstilling av agrarkjemisk anvendelige virkestoffer, fremstilte forbindelser, anvendelsen av disse og biologisk rene kulturer av sorangium cellulosum som anvendes i fremgangsmåten
PL307238A1 (en)	1995-05-15	Derivatives of ng-monomethyl-l-arginin hydrochloride and their application in treating septic shocks
CO5640115A2 (es)	2006-05-31	3,4-dihidropirido [1,2-a] pirimidinas sustituidas
AU8079891A (en)	1992-01-23	Bile alcohol and drug containing the same as active ingredient
HK1011278A1 (en)	1999-07-09	Macrolide formulations
IT8921516A0 (it)	1989-08-11	Procedimento di microincapsulazione di microorganismi vivi e composizioni farmaceutiche stabili.
IT1254938B (it)	1995-10-11	Derivati otticamente attivi della n-imminoalchil-n'-((2-idrossi- 2-fenil-2-cicloesil)-etil)-piperazina
MX9101804A (es)	1993-04-01	Composicion para preparaciones farmaceuticas solidas con vitaminas de activas y procedimiento para la preparacion de las mismas
ITVR920023A0 (it)	1992-03-23	Struttura di supporto per tavoli sedie scaffalerie e simili costituita da elementi modulari
FR2655344B1 (fr)	1992-04-03	Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.
FR2661677B1 (fr)	1992-08-21	Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.