DK0639176T3 - Benzendimethanolderivat, der er egnet til mikronisering - Google Patents

Benzendimethanolderivat, der er egnet til mikronisering

Info

Publication number: DK0639176T3
Authority: DK; Denmark
Prior art keywords: salt; micronization; benzene dimethanol; derivative suitable; hydroxy
Prior art date: 1990-11-29

Application number

DK92900167.5T

Other languages

Danish (da)

English (en)

Inventor

Steven Frederick Beach

David William Stuart Latham

Tony Gordon Roberts

Colin Brian Sidgwick

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-29

Filing date

1991-11-28

Publication date

1996-12-23

1991-11-28 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1996-12-23 Application granted granted Critical

1996-12-23 Publication of DK0639176T3 publication Critical patent/DK0639176T3/da

Links

GCBSCAKBRSMFCP-UHFFFAOYSA-N benzene;methanol Chemical class OC.OC.C1=CC=CC=C1 GCBSCAKBRSMFCP-UHFFFAOYSA-N 0.000 title 1
UPHOPMSGKZNELG-UHFFFAOYSA-N 2-hydroxynaphthalene-1-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=C(O)C=CC2=C1 UPHOPMSGKZNELG-UHFFFAOYSA-N 0.000 abstract 1
SWPCURCTHNTSKL-UHFFFAOYSA-N C1=CC=CC2=C(O)C(C(=O)O)=CC=C21.C1=CC=C2C(C(=O)O)=C(O)C=CC2=C1 Chemical compound C1=CC=CC2=C(O)C(C(=O)O)=CC=C21.C1=CC=C2C(C(=O)O)=C(O)C=CC2=C1 SWPCURCTHNTSKL-UHFFFAOYSA-N 0.000 abstract 1
239000002152 aqueous-organic solution Substances 0.000 abstract 1
125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000013081 microcrystal Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
238000010791 quenching Methods 0.000 abstract 1
230000000171 quenching effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
- C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polyesters Or Polycarbonates (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Fats And Perfumes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)

DK92900167.5T 1990-11-29 1991-11-28 Benzendimethanolderivat, der er egnet til mikronisering DK0639176T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909026005A GB9026005D0 (en)	1990-11-29	1990-11-29	Drug material suitable for micronisation

Publications (1)

Publication Number	Publication Date
DK0639176T3 true DK0639176T3 (da)	1996-12-23

Family

ID=10686212

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92900167.5T DK0639176T3 (da)	1990-11-29	1991-11-28	Benzendimethanolderivat, der er egnet til mikronisering

Country Status (27)

Country	Link
US (1)	US5380922A (cs)
EP (2)	EP0639176B1 (cs)
JP (1)	JP3375626B2 (cs)
KR (1)	KR100192196B1 (cs)
AT (1)	ATE144244T1 (cs)
AU (1)	AU644505B2 (cs)
BG (1)	BG61340B1 (cs)
CA (1)	CA2099586C (cs)
CY (1)	CY2009A (cs)
CZ (1)	CZ282996B6 (cs)
DE (1)	DE69122780T2 (cs)
DK (1)	DK0639176T3 (cs)
ES (1)	ES2093812T3 (cs)
FI (2)	FI118155B (cs)
GB (1)	GB9026005D0 (cs)
GR (1)	GR3022088T3 (cs)
HK (1)	HK78997A (cs)
HU (1)	HU218205B (cs)
IE (1)	IE914146A1 (cs)
OA (2)	OA09861A (cs)
PL (2)	PL169722B1 (cs)
RU (2)	RU2116293C1 (cs)
SG (1)	SG49741A1 (cs)
SK (1)	SK281095B6 (cs)
TW (1)	TW309425B (cs)
WO (1)	WO1992009557A1 (cs)
ZA (1)	ZA919401B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9026005D0 (en) *	1990-11-29	1991-01-16	Glaxo Group Ltd	Drug material suitable for micronisation
WO1993016031A1 (en) *	1992-02-11	1993-08-19	Glaxo Group Limited	Benzenedimethanol derivative suitable for micronisation
US6254882B1 (en)	1997-09-16	2001-07-03	Sepracor Inc.	Methods and compositions for treating pulmonary disorders using optically pure (S)—salmeterol
US7090831B1 (en)	1999-04-14	2006-08-15	Smithkline Beecham Corporation	Pharmaceutical aerosol formulation
WO2002026239A1 (en)	2000-09-26	2002-04-04	Temple University Of The Commonwealth System Of Higher Education	Analgesic and glucosamine compositions
EP2127641A1 (en)	2008-05-26	2009-12-02	Inke, S.A.	Micronisable form of salmeterol xinafoate
KR101100614B1 (ko)	2010-09-20	2011-12-29	한국수력원자력 주식회사	농축폐액 건조물의 펠렛화 장치 및 방법과 이를 이용한 유리조성개발 방법
WO2016142582A1 (en)	2015-03-11	2016-09-15	Fermion Oy	Process for the preparation of crystalline salmeterol and its xinafoate salt

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZW6584A1 (en) *	1983-04-18	1985-04-17	Glaxo Group Ltd	Phenethanolamine derivatives
GB9026005D0 (en) *	1990-11-29	1991-01-16	Glaxo Group Ltd	Drug material suitable for micronisation

1990
- 1990-11-29 GB GB909026005A patent/GB9026005D0/en active Pending
1991
- 1991-11-28 PL PL91308211A patent/PL169722B1/pl unknown
- 1991-11-28 RU RU93040704A patent/RU2116293C1/ru active
- 1991-11-28 EP EP92900167A patent/EP0639176B1/en not_active Expired - Lifetime
- 1991-11-28 HU HU9301568A patent/HU218205B/hu unknown
- 1991-11-28 CA CA002099586A patent/CA2099586C/en not_active Expired - Lifetime
- 1991-11-28 AT AT92900167T patent/ATE144244T1/de not_active IP Right Cessation
- 1991-11-28 SK SK545-93A patent/SK281095B6/sk not_active IP Right Cessation
- 1991-11-28 PL PL91299352A patent/PL167976B1/pl unknown
- 1991-11-28 AU AU90402/91A patent/AU644505B2/en not_active Ceased
- 1991-11-28 RU RU97121416/04A patent/RU2197475C2/ru active
- 1991-11-28 IE IE414691A patent/IE914146A1/en not_active IP Right Cessation
- 1991-11-28 WO PCT/GB1991/002108 patent/WO1992009557A1/en not_active Ceased
- 1991-11-28 DK DK92900167.5T patent/DK0639176T3/da active
- 1991-11-28 JP JP50047092A patent/JP3375626B2/ja not_active Expired - Lifetime
- 1991-11-28 ES ES92900167T patent/ES2093812T3/es not_active Expired - Lifetime
- 1991-11-28 SG SG1996004594A patent/SG49741A1/en unknown
- 1991-11-28 DE DE69122780T patent/DE69122780T2/de not_active Expired - Lifetime
- 1991-11-28 CZ CS931019A patent/CZ282996B6/cs not_active IP Right Cessation
- 1991-11-28 ZA ZA919401A patent/ZA919401B/xx unknown
1992
- 1992-05-21 EP EP92304635A patent/EP0571669B1/en not_active Expired - Lifetime
- 1992-05-29 TW TW081104199A patent/TW309425B/zh active
1993
- 1993-05-14 US US08/050,298 patent/US5380922A/en not_active Expired - Lifetime
- 1993-05-14 OA OA60370A patent/OA09861A/en unknown
- 1993-05-25 BG BG97767A patent/BG61340B1/bg unknown
- 1993-05-27 KR KR1019930701589A patent/KR100192196B1/ko not_active Expired - Lifetime
- 1993-05-27 FI FI932422A patent/FI118155B/fi not_active IP Right Cessation
- 1993-09-24 OA OA60416A patent/OA10024A/en unknown
1996
- 1996-12-18 GR GR960403534T patent/GR3022088T3/el unknown
1997
- 1997-06-12 HK HK78997A patent/HK78997A/en not_active IP Right Cessation
1998
- 1998-02-20 CY CY200998A patent/CY2009A/xx unknown
- 1998-09-28 FI FI982081A patent/FI118203B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0639176B1 (en)	1996-10-16
WO1992009557A1 (en)	1992-06-11
FI982081A0 (fi)	1998-09-28
DE69122780D1 (de)	1996-11-21
RU2116293C1 (ru)	1998-07-27
SK281095B6 (sk)	2000-11-07
US5380922A (en)	1995-01-10
JP3375626B2 (ja)	2003-02-10
SK54593A3 (en)	1993-10-06
OA09861A (en)	1994-08-15
FI118155B (fi)	2007-07-31
GB9026005D0 (en)	1991-01-16
FI118203B (fi)	2007-08-31
PL169722B1 (pl)	1996-08-30
FI932422A0 (fi)	1993-05-27
ATE144244T1 (de)	1996-11-15
EP0639176A1 (en)	1995-02-22
AU644505B2 (en)	1993-12-09
CZ282996B6 (cs)	1997-12-17
CA2099586C (en)	2002-06-25
FI982081L (fi)	1998-09-28
GR3022088T3 (en)	1997-03-31
RU2197475C2 (ru)	2003-01-27
SG49741A1 (en)	1998-06-15
CA2099586A1 (en)	1992-05-30
ZA919401B (en)	1992-07-29
BG97767A (bg)	1994-12-02
HU218205B (hu)	2000-06-28
TW309425B (cs)	1997-07-01
EP0571669B1 (en)	1996-03-06
ES2093812T3 (es)	1997-01-01
PL167976B1 (pl)	1995-12-30
AU9040291A (en)	1992-06-25
BG61340B1 (en)	1997-06-30
CY2009A (en)	1998-02-20
EP0571669A1 (en)	1993-12-01
DE69122780T2 (de)	1997-02-20
JPH06503082A (ja)	1994-04-07
CZ101993A3 (en)	1994-01-19
KR100192196B1 (en)	1999-06-15
HK78997A (en)	1997-06-20
FI932422L (fi)	1993-05-27
IE914146A1 (en)	1992-06-03
OA10024A (en)	1996-10-14
HU9301568D0 (en)	1993-09-28
HUT64219A (en)	1993-12-28

Publication	Publication Date	Title
DK0639176T3 (da)	1996-12-23	Benzendimethanolderivat, der er egnet til mikronisering
FI894718A0 (fi)	1989-10-05	Pigmentationssupplement foer djurfoderkompositioner.
ES2061179T3 (es)	1994-12-01	Preparaciones granuladas y metodo para producirlas.
MX9206952A (es)	1993-06-01	Polvo de dispercion redispersable a partir de un copolimerizado de acetato de vinilo de n-vinilpirrolidona su preparcion y su empleo
FR2656526B1 (fr)	1994-10-28	Dispositif a liberation controlee et procede de preparation.
EP0371535A3 (en)	1991-08-28	Fabric treatment composition
RU93040704A (ru)	1996-06-20	1-гидрокси-2-нафталинкарбоксилатная соль 4-гидрокси-альфа-[[[6-(4-фенилбутокси)гексил]амино]метил]-1,3-бензолдиметанола в форме сферических сращений микрокристаллов, способ ее измельчения, способ ее получения, применение гидроксинафтоата для получения измельченной гидроксинафтоатной соли
JPS6413004A (en)	1989-01-17	Sustained release ferrous sulfate
DK0590382T3 (da)	1996-08-26	Fremgangsmåde til fremstilling af pellets af et efedrinderivat
MY108410A (en)	1996-09-30	Drug material suitable for micronisation.
ES2034805T3 (es)	1993-04-01	Procedimiento para la obtencion de pellets de derivados de xantina.
Verkhovskii et al.	1990	Structure and Properties of Steels After Quenching in Magnetic Liquid
CA2003494A1 (en)	1990-05-28	Fabric treatment composition
Nakae	1988	The Role of Solidification in Developing Materials
Marinskii et al.	1988	Examination of the Effect of Working Parameters on the Temperature and Energy Parameters of Electroslag Crucible Melting
YU56692A (sh)	1994-11-15	Novi, za mikronizaciju pogodan oblik 1-hidrok-si-2-naftalin-karboksilatne soli 4-hidroksi-alfa1-///6-(4-fenilbutoksi)-hebsil/amino/metil/-1,3 benzoldimetanola i postupak za njegovo dobijanje
NO862907D0 (no)	1986-07-18	Fremgangsmaate for fremstilling av et farmasoeytisk preparat med forsinket virkestoff - frigjoering.
KOLOMEEV et al.	1989	Climatic consequences of the movement of smoke to the stratosphere(Klimaticheskie posledstviia vynosa dyma v stratosferu)
Blokhina et al.	1989	Thermal Treatment of High-Dispersed Palladium Powders
JPS5528926A (en)	1980-02-29	Preparation of 5-fluoro-uridine
Jurci et al.	1998	Microstructural Development and Phase Transformations in Fe-4 C-12 Cr-13 V RS Powder during Annealing
Kenis et al.	1988	Optimum Control of Cooling Kinetics of the Solid Cylinder in a Sprayer
Golub et al.	1991	Temperature Dependence of the Titanium Carbide Young Modulus and Eutectic Chromium--Titanium Carbide Alloys
Zenker	1990	Heat Treatment by Electron Beam
Paton et al.	1988	Role of Installations for Horizontal Continuous of Billets in Electroslag Technology