DK0667902T3 - CDR-graftede humaniserede, kimæriske T-celle-antistoffer - Google Patents

CDR-graftede humaniserede, kimæriske T-celle-antistoffer

Info

Publication number
DK0667902T3
DK0667902T3 DK92924782T DK92924782T DK0667902T3 DK 0667902 T3 DK0667902 T3 DK 0667902T3 DK 92924782 T DK92924782 T DK 92924782T DK 92924782 T DK92924782 T DK 92924782T DK 0667902 T3 DK0667902 T3 DK 0667902T3
Authority
DK
Denmark
Prior art keywords
pct
cdr grafted
cell antibodies
humanized chimeric
grafted humanized
Prior art date
Application number
DK92924782T
Other languages
Danish (da)
English (en)
Inventor
Herman Waldmann
Louise Walsh
Alan Peter Lewis
James Scott Crowe
Original Assignee
Univ Cambridge Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cambridge Tech filed Critical Univ Cambridge Tech
Application granted granted Critical
Publication of DK0667902T3 publication Critical patent/DK0667902T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2806Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/867Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody produced via recombinant dna technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK92924782T 1991-12-06 1992-12-04 CDR-graftede humaniserede, kimæriske T-celle-antistoffer DK0667902T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919125979A GB9125979D0 (en) 1991-12-06 1991-12-06 Antibody
PCT/GB1992/002251 WO1993011237A1 (en) 1991-12-06 1992-12-04 Cdr grafted humanised chimeric t-cell antibodies

Publications (1)

Publication Number Publication Date
DK0667902T3 true DK0667902T3 (da) 2003-04-22

Family

ID=10705825

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92924782T DK0667902T3 (da) 1991-12-06 1992-12-04 CDR-graftede humaniserede, kimæriske T-celle-antistoffer

Country Status (9)

Country Link
US (1) US5502167A (de)
EP (1) EP0667902B1 (de)
JP (1) JP3339637B2 (de)
AT (1) ATE234923T1 (de)
DE (1) DE69232968T2 (de)
DK (1) DK0667902T3 (de)
ES (1) ES2194011T3 (de)
GB (1) GB9125979D0 (de)
WO (1) WO1993011237A1 (de)

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US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
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GB9125979D0 (en) * 1991-12-06 1992-02-05 Wellcome Found Antibody

Also Published As

Publication number Publication date
EP0667902B1 (de) 2003-03-19
WO1993011237A1 (en) 1993-06-10
ES2194011T3 (es) 2003-11-16
DE69232968T2 (de) 2003-11-06
GB9125979D0 (en) 1992-02-05
DE69232968D1 (de) 2003-04-24
JP3339637B2 (ja) 2002-10-28
ATE234923T1 (de) 2003-04-15
US5502167A (en) 1996-03-26
JPH07504808A (ja) 1995-06-01
EP0667902A1 (de) 1995-08-23

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