DK0693941T3 - Radiomærkede forbindelser til trombe-billeddannelse - Google Patents

Radiomærkede forbindelser til trombe-billeddannelse

Info

Publication number: DK0693941T3
Authority: DK; Denmark
Prior art keywords: pct; compounds; methods; sec; date
Prior art date: 1993-04-08

Application number

DK94921885T

Other languages

English (en)

Inventor

John Lister-James

Edward R Civitello

William Mcbride

Richard T Dean

Original Assignee

Diatide Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-08

Filing date

1994-04-08

Publication date

2002-10-14

1994-04-08 Application filed by Diatide Inc filed Critical Diatide Inc

2002-10-14 Application granted granted Critical

2002-10-14 Publication of DK0693941T3 publication Critical patent/DK0693941T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 4
208000007536 Thrombosis Diseases 0.000 title 1
238000003384 imaging method Methods 0.000 title 1
238000000034 method Methods 0.000 abstract 3
102000005962 receptors Human genes 0.000 abstract 2
108020003175 receptors Proteins 0.000 abstract 2
102100025306 Integrin alpha-IIb Human genes 0.000 abstract 1
101710149643 Integrin alpha-IIb Proteins 0.000 abstract 1
GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 abstract 1
230000027455 binding Effects 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000012216 imaging agent Substances 0.000 abstract 1
-1 peptides Chemical class 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000009870 specific binding Effects 0.000 abstract 1
229940056501 technetium 99m Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Physics & Mathematics (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Investigating Or Analysing Biological Materials (AREA)
Surgical Instruments (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measurement Of Radiation (AREA)

DK94921885T 1993-04-08 1994-04-08 Radiomærkede forbindelser til trombe-billeddannelse DK0693941T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4482593A	1993-04-08	1993-04-08
PCT/US1994/003878 WO1994023758A1 (en)	1993-04-08	1994-04-08	Radiolabeled compounds for thrombus imaging

Publications (1)

Publication Number	Publication Date
DK0693941T3 true DK0693941T3 (da)	2002-10-14

Family

ID=21934541

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94921885T DK0693941T3 (da)	1993-04-08	1994-04-08	Radiomærkede forbindelser til trombe-billeddannelse

Country Status (13)

Country	Link
US (1)	US6056940A (da)
EP (1)	EP0693941B1 (da)
JP (1)	JP2954355B2 (da)
AT (1)	ATE220926T1 (da)
AU (1)	AU687080B2 (da)
BR (1)	BR1100946A (da)
CA (2)	CA2363780C (da)
DE (1)	DE69431052T2 (da)
DK (1)	DK0693941T3 (da)
ES (1)	ES2179076T3 (da)
SG (1)	SG49788A1 (da)
WO (1)	WO1994023758A1 (da)
ZA (1)	ZA942439B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5997844A (en) *	1991-02-08	1999-12-07	Diatide, Inc.	Technetium-99m labeled peptides for imaging
US5849261A (en) *	1991-02-08	1998-12-15	Diatide, Inc.	Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5965107A (en) *	1992-03-13	1999-10-12	Diatide, Inc.	Technetium-99m labeled peptides for imaging
US5736122A (en) *	1991-02-08	1998-04-07	Diatide, Inc.	Technetium-99m labeled peptides for thrombus imaging
US5830856A (en) *	1991-02-08	1998-11-03	Diatide, Inc.	Radiolabeled compounds for thrombus imaging
US5645815A (en) *	1991-02-08	1997-07-08	Diatide, Inc.	Radiolabled compounds for thrombus imaging
US7238340B1 (en) *	1991-11-27	2007-07-03	Cis Bio International	Monoamine, diamide, thiol-containing metal chelating agents
JP2774378B2 (ja) *	1991-02-08	1998-07-09	ダイアテク，インコーポレイテッド	映像用テクネチウム−９９ｍ標識化ポリペプチド
US6019958A (en) *	1991-02-08	2000-02-01	Diatide, Inc.	Technetium-99m labeled peptides for imaging inflammation
US5443815A (en) *	1991-11-27	1995-08-22	Diatech, Inc.	Technetium-99m labeled peptides for imaging
US5989519A (en) *	1992-03-13	1999-11-23	Diatide, Inc.	Technetium-99m labeled peptides for imaging inflammation
US5508020A (en) *	1992-06-05	1996-04-16	Diatech, Inc.	Technetium-99M labeled peptides for imaging
US5968476A (en) *	1992-05-21	1999-10-19	Diatide, Inc.	Technetium-99m labeled peptides for thrombus imaging
DE69529988T2 (de) *	1994-05-02	2003-12-11	Diatide, Inc.	Technetium-99m markierte bildformungsmittel
US5753206A (en) *	1995-06-07	1998-05-19	Immunomedics, Inc.	Radiometal-binding analogues of luteinizing hormone releasing hormone
EP0975374B1 (en)	1996-07-12	2007-12-05	Immunomedics, Inc.	Radiometal-binding peptide analogues
US5951981A (en) *	1996-12-02	1999-09-14	Diatide, Inc.	Thrombolytic agents with antithrombotic activity
US5886142A (en) *	1997-05-20	1999-03-23	Thomas Jefferson University	Radiolabeled thrombus imaging agents
DE10005631A1 (de) *	2000-02-09	2001-08-23	Max Planck Gesellschaft	Arginin-Mimetika als Faktor X¶a¶-Inhibitoren
AU2004226464A1 (en) *	2003-03-26	2004-10-14	Cardiomind, Inc.	Implant delivery technologies

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US4578079A (en) *	1982-08-04	1986-03-25	La Jolla Cancer Research Foundation	Tetrapeptide
US4792525A (en) *	1982-08-04	1988-12-20	La Jolla Cancer Research Foundation	Tetrapeptide
US5225181A (en) *	1985-06-07	1993-07-06	The Research Foundation Of State University Of New York	Radiolabeled antiplatelet monoclonal antibody for imaging in-vivo thrombi
US4877868A (en) *	1986-03-12	1989-10-31	Neorx Corporation	Radionuclide antibody coupling
CA1335725C (en) *	1987-09-25	1995-05-30	Stephen W. Hadley	Method of diagnosing blood clots using fibrin-binding proteins
AU639409B2 (en) *	1987-12-10	1993-07-29	La Jolla Cancer Research Foundation	Conformationally stabilized cell adhesion peptides
EP0381713B1 (en) *	1988-04-29	1994-01-19	Mallinckrodt, Inc.	Diaminedithiol chelating agents for radiopharmaceuticals
US5196510A (en) *	1988-12-29	1993-03-23	Cytogen Corporation	Molecular recognition units
US4986979A (en) *	1989-03-14	1991-01-22	Neorx Corporation	Imaging tissue sites of inflammation
GB8914020D0 (en) *	1989-06-19	1989-08-09	Antisoma Ltd	Synthetic peptides for use in thrombus detection
US5384309A (en) *	1989-07-17	1995-01-24	Genentech, Inc.	Cyclized peptides and their use as platelet aggregation inhibitors
EP0410537A1 (en) *	1989-07-28	1991-01-30	Merck & Co. Inc.	Fibrinogen receptor antagonists
CA2021951A1 (en) *	1989-07-28	1991-01-29	Ruth F. Nutt	Fibrinogen receptor antagonists
EP0410539A1 (en) *	1989-07-28	1991-01-30	Merck & Co. Inc.	Fibrinogen receptor antagonists
EP0410541A1 (en) *	1989-07-28	1991-01-30	Merck & Co. Inc.	Fibrinogen receptor antagonists
US5443816A (en) *	1990-08-08	1995-08-22	Rhomed Incorporated	Peptide-metal ion pharmaceutical preparation and method
US4952562A (en) *	1989-09-29	1990-08-28	Rorer Pharmaceutical Corporation	Anti-thrombotic peptides and pseudopeptides
NZ235563A (en) *	1989-10-13	1993-04-28	Merck & Co Inc	Fibrinogen receptor antagonist and pharmaceutical composition
NZ235564A (en) *	1989-10-13	1993-10-26	Merck & Co Inc	Fibrinogen receptor antagonist and pharmaceutical compositions
CA2027936C (en) *	1989-10-23	2001-07-24	Smithkline Beecham Corporation	Cyclic anti-aggregatory peptides
US5086069A (en) *	1990-02-05	1992-02-04	Rorer Pharmaceutical Corporation	Anti-thrombotic peptide and pseudopeptide derivatives
IL97459A0 (en) *	1990-03-09	1992-06-21	Hybritech Inc	Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
WO1991015515A1 (en) *	1990-04-06	1991-10-17	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5105327A (en) *	1990-05-10	1992-04-14	Uses, Inc.	Ac power conditioning circuit
IL99537A (en) *	1990-09-27	1995-11-27	Merck & Co Inc	Fibrinogen receptor antagonists and pharmaceutical compositions containing them
US5965107A (en) *	1992-03-13	1999-10-12	Diatide, Inc.	Technetium-99m labeled peptides for imaging
JP2774378B2 (ja) *	1991-02-08	1998-07-09	ダイアテク，インコーポレイテッド	映像用テクネチウム−９９ｍ標識化ポリペプチド
US5645815A (en) *	1991-02-08	1997-07-08	Diatide, Inc.	Radiolabled compounds for thrombus imaging
ATE114670T1 (de) *	1991-03-06	1994-12-15	Searle & Co	Phenylamidinderivate als plättchenaggregationsinhibitoren.
CA2106314A1 (en) *	1991-04-05	1992-10-06	John P. Burnier	Platelet aggregation inhibitors having high specification for gpiibiiia
US5321034A (en) *	1991-05-07	1994-06-14	Merck & Co., Inc.	Fibrinogen receptor antagonists
US5220050A (en) *	1991-05-17	1993-06-15	G. D. Searle & Co.	Peptide mimetic compounds useful as platelet aggregation inhibitors
AU666318B2 (en) *	1991-06-28	1996-02-08	Smithkline Beecham Corporation	Bicyclic fibrinogen antagonists
US5250679A (en) *	1991-10-18	1993-10-05	Genentech, Inc.	Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5508020A (en) *	1992-06-05	1996-04-16	Diatech, Inc.	Technetium-99M labeled peptides for imaging
ATE329624T1 (de) *	1992-05-21	2006-07-15	Diatide Inc	Technetium-99m markierte peptide zur bilderzeugung von thrombus
US5879657A (en) *	1993-03-30	1999-03-09	The Dupont Merck Pharmaceutical Company	Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5744120A (en) *	1993-03-30	1998-04-28	The Dupont Merick Pharmaceutical Company	Ternary radiopharmaceutical complexes

1994
- 1994-04-08 WO PCT/US1994/003878 patent/WO1994023758A1/en not_active Ceased
- 1994-04-08 CA CA002363780A patent/CA2363780C/en not_active Expired - Fee Related
- 1994-04-08 DK DK94921885T patent/DK0693941T3/da active
- 1994-04-08 ZA ZA942439A patent/ZA942439B/xx unknown
- 1994-04-08 CA CA002160120A patent/CA2160120A1/en not_active Abandoned
- 1994-04-08 AT AT94921885T patent/ATE220926T1/de not_active IP Right Cessation
- 1994-04-08 JP JP6523329A patent/JP2954355B2/ja not_active Expired - Fee Related
- 1994-04-08 ES ES94921885T patent/ES2179076T3/es not_active Expired - Lifetime
- 1994-04-08 DE DE69431052T patent/DE69431052T2/de not_active Expired - Fee Related
- 1994-04-08 AU AU72413/94A patent/AU687080B2/en not_active Ceased
- 1994-04-08 US US08/535,170 patent/US6056940A/en not_active Expired - Fee Related
- 1994-04-08 EP EP94921885A patent/EP0693941B1/en not_active Expired - Lifetime
- 1994-04-08 SG SG1996006000A patent/SG49788A1/en unknown
1997
- 1997-05-14 BR BR1100946-2A patent/BR1100946A/pt active IP Right Grant

Also Published As

Publication number	Publication date
EP0693941A1 (en)	1996-01-31
DE69431052D1 (de)	2002-08-29
SG49788A1 (en)	1998-06-15
CA2160120A1 (en)	1994-10-27
BR1100946A (pt)	2000-08-08
ZA942439B (en)	1996-01-08
EP0693941B1 (en)	2002-07-24
CA2363780A1 (en)	1994-10-27
AU687080B2 (en)	1998-02-19
CA2363780C (en)	2003-01-07
ES2179076T3 (es)	2003-01-16
JPH08508999A (ja)	1996-09-24
JP2954355B2 (ja)	1999-09-27
US6056940A (en)	2000-05-02
WO1994023758A1 (en)	1994-10-27
DE69431052T2 (de)	2003-03-13
AU7241394A (en)	1994-11-08
ATE220926T1 (de)	2002-08-15

Publication	Publication Date	Title
DK0693941T3 (da)	2002-10-14	Radiomærkede forbindelser til trombe-billeddannelse
DE69326335D1 (de)	1999-10-14	Technetium-99M-markierte peptide zur Bilderzeugung
DK0641222T3 (da)	2000-12-11	Peptider mærket med technetium-99m til trombeafbildning
DK0644778T3 (da)	1997-11-03	Technetium-99-mærkede peptider til imagografi
ATE340594T1 (de)	2006-10-15	Somatostatin bindende peptide-metallchelat konjugate
MX9707426A (es)	1998-07-31	Peptidos marcados radioactivamente para diagnostico y terapia.
CA2156390A1 (en)	1994-09-01	Technetium-99m labeled peptides for diagnostic imaging
DK0630265T3 (da)	2003-06-30	Technetium-99m mærkede peptider til afbildning af inflammation
AU598183B2 (en)	1990-06-21	Coupling agents for radiolabeled antibody fragments
DK0570493T3 (da)	2000-06-26	Technetium-99m-mærkede polypeptider til billeddannelse.
CA2124458A1 (en)	1993-06-10	Technetium-99m Labeled Peptides for Imaging
DK0804481T3 (da)	2003-07-28	Somatostatin-derivater og deres radioaktivt mærkede produkter
PT762901E (pt)	2006-08-31	Peptidos marcados com tecnecio-99m para imagiologia.
TR200002257T2 (tr)	2000-12-21	Nükleer reseptör ligandları ve ligand bağlanma domainleri.
ATE234639T1 (de)	2003-04-15	Technetium-99m markierte bildformungsmittel
ZA952206B (en)	1995-12-12	Scintigraphic imaging agents