DK0699207T3 - Mellemprodukt til azithromycin - Google Patents

Mellemprodukt til azithromycin

Info

Publication number: DK0699207T3
Authority: DK; Denmark
Prior art keywords: pct; date nov; sec; iii; compound
Prior art date: 1993-05-19

Application number

DK94914706.0T

Other languages

Danish (da)

English (en)

Inventor

Bingwei V Yang

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-19

Filing date

1994-03-14

Publication date

1997-12-08

1994-03-14 Application filed by Pfizer filed Critical Pfizer

1997-12-08 Application granted granted Critical

1997-12-08 Publication of DK0699207T3 publication Critical patent/DK0699207T3/da

Links

MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 title abstract 2
229960004099 azithromycin Drugs 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK94914706.0T 1993-05-19 1994-03-14 Mellemprodukt til azithromycin DK0699207T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6461093A	1993-05-19	1993-05-19

Publications (1)

Publication Number	Publication Date
DK0699207T3 true DK0699207T3 (da)	1997-12-08

Family

ID=22057118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94914706.0T DK0699207T3 (da)	1993-05-19	1994-03-14	Mellemprodukt til azithromycin

Country Status (12)

Country	Link
US (1)	US5686587A (de)
EP (1)	EP0699207B1 (de)
JP (1)	JP2696608B2 (de)
AT (1)	ATE154806T1 (de)
CA (1)	CA2162401C (de)
DE (1)	DE69403963T2 (de)
DK (1)	DK0699207T3 (de)
ES (1)	ES2104386T3 (de)
FI (1)	FI110781B (de)
GR (1)	GR3024297T3 (de)
HR (1)	HRP940271B1 (de)
WO (1)	WO1994026758A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20020231A2 (en)	2002-03-18	2003-12-31	Pliva D D	ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
ES2122905B1 (es) *	1996-07-11	1999-11-16	Astur Pharma Sa	Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
GB9705323D0 (en) *	1997-03-14	1997-04-30	Biochemie Sa	Organic compounds
PT102006B (pt) *	1997-05-19	2000-06-30	Hovione Sociedade Quimica S A	Novo processo de preparacao de azitromicina
HRP980189B1 (en) *	1998-04-06	2004-04-30	Pliva Pharm & Chem Works	Novel 15-membered lactams ketolides
GB9824580D0 (en) *	1998-11-10	1999-01-06	Biochemie Sa	Organic compounds
US6764996B1 (en)	1999-08-24	2004-07-20	Abbott Laboratories	9a-azalides with antibacterial activity
DK1206476T3 (da) *	1999-08-24	2006-05-15	Abbott Lab	9a-azalider med antibakteriel virkning
ES2177373B1 (es) *	1999-11-26	2003-11-01	Astur Pharma Sa	Preparacion de azitromicina en su forma no cristalina
DE60026718T2 (de) *	2000-07-25	2006-11-16	Laboratorio Silanes, S.A. De C.V.	Einstufiges verfahren zur herstellung von 7,16-deoxy-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihydroxi-6-ethyl-3,5,9,11,13,15-hexamethylbicycle(11.2.11)hexadeca-1(2)-en-8-ona undeine neue form von 9-desoxo-9a-methyl-9a-aza-9a-homoerythromycin a
JP2004506664A (ja) *	2000-08-23	2004-03-04	ウォックハート・リミテッド	無水アジトロマイシンの製造法
ES2179756B1 (es) *	2000-11-30	2004-10-01	Ercros Industrial, S.A.	Procedimiento de obtencion de azaeritromicina.
SI1390377T1 (sl)	2001-05-22	2006-06-30	Pfizer Prod Inc	Nova kristalna oblika azitromicina
CA2458135A1 (en) *	2001-08-21	2003-03-06	Pfizer Products Inc.	Single dose azithromycin for treating respiratory infections
HRP20020614A2 (en) *	2002-07-22	2004-06-30	PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o.	Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US6645941B1 (en) *	2003-03-26	2003-11-11	Enanta Pharmaceuticals, Inc.	6,11-3C-bicyclic 9a-azalide derivatives
WO2005030227A1 (en) *	2003-09-23	2005-04-07	Enanta Pharmaceuticals, Inc.	9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
WO2005070113A2 (en) *	2004-01-09	2005-08-04	Enanta Pharmaceuticals, Inc.	9n-substituted 6-11 bicyclic erythromycin derivatives
US7468428B2 (en)	2004-03-17	2008-12-23	App Pharmaceuticals, Llc	Lyophilized azithromycin formulation
WO2006011160A1 (en)	2004-06-28	2006-02-02	Alembic Limited	Process for the preparation of azithromycin monohydrate isopropanol clathrate
US7384922B2 (en) *	2005-05-04	2008-06-10	Enanta Pharmaceuticals, Inc.	6-11 bridged oxime erythromycin derivatives
WO2007015265A2 (en) *	2005-05-24	2007-02-08	Kopran Research Laboratories Ltd	A process for preparing 6,9-imino ether
US7407942B2 (en) *	2006-03-29	2008-08-05	Emata Pharmaceuticals, Inc	3,6-bridged 9,12-oxolides
CN102863486A (zh) *	2012-09-18	2013-01-09	太仓市运通化工厂	一种9-脱氧-9a-氮杂-9a-高红霉素的合成方法
CN104262429A (zh) *	2014-10-03	2015-01-07	菏泽市方明制药有限公司	一种阿奇霉素的纯化方法
CN108530494B (zh) *	2018-06-29	2021-03-30	宜昌东阳光生化制药有限公司	一种阿奇霉素重排杂质r的合成方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU43116B (en) *	1979-04-02	1989-04-30	Pliva Pharm & Chem Works	Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
SI8110592A8 (en) *	1981-03-06	1996-06-30	Pliva Pharm & Chem Works	Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4382085A (en) *	1982-03-01	1983-05-03	Pfizer Inc.	4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
US4474768A (en) *	1982-07-19	1984-10-02	Pfizer Inc.	N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4526889A (en) *	1982-11-15	1985-07-02	Pfizer Inc.	Epimeric azahomoerythromycin A derivative, intermediates and method of use
US4464527A (en) *	1983-06-30	1984-08-07	Pfizer Inc.	Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
YU43658B (en) *	1983-07-18	1989-10-31	Pliva Pharm & Chem Works	Process for preparing 7,16-dioxa-2-aza-10-0-cladinosyl-12,0-desosaminyl-4,5-dihydroxy-6-ethyl-3,5,9,11,13,15-hexamethyl-bicyclo(11.2.1)hexadeca-1(2)-ene-8
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) *	1984-04-13	1985-04-23	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
CA2062932A1 (en) *	1991-03-15	1992-09-16	Robert R. Wilkening	9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives thereof
US5912331A (en) *	1991-03-15	1999-06-15	Merck & Co., Inc.	Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
CA2064634C (en) *	1991-04-04	1998-08-04	James V. Heck	9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5202434A (en) *	1991-04-05	1993-04-13	Merck & Co., Inc.	8a-aza-8a-homoerythromycin lactams
CA2065222A1 (en) *	1991-04-09	1992-10-10	Robert R. Wilkening	Process for the preparation of 8a-aza-8a-homoerythromycin cyclic iminoethers
EP0508795A1 (de) *	1991-04-10	1992-10-14	Merck & Co. Inc.	8A-Aza-8A-homoerythromycin Cyclischiminoethere
US5189159A (en) *	1992-04-02	1993-02-23	Merck & Co., Inc.	8a-AZA-8a-homoerythromycin cyclic iminoethers
CA2065218A1 (en) *	1991-04-11	1992-10-12	Robert R. Wilkening	Process for the preparation of 9-deoxo-8a-aza-8a-homoerythromycin a and its 8a-alkyl derivatives

1994
- 1994-03-14 US US08/537,741 patent/US5686587A/en not_active Expired - Fee Related
- 1994-03-14 WO PCT/US1994/002547 patent/WO1994026758A1/en not_active Ceased
- 1994-03-14 CA CA002162401A patent/CA2162401C/en not_active Expired - Fee Related
- 1994-03-14 DK DK94914706.0T patent/DK0699207T3/da active
- 1994-03-14 DE DE69403963T patent/DE69403963T2/de not_active Expired - Fee Related
- 1994-03-14 JP JP6525396A patent/JP2696608B2/ja not_active Expired - Fee Related
- 1994-03-14 EP EP94914706A patent/EP0699207B1/de not_active Expired - Lifetime
- 1994-03-14 ES ES94914706T patent/ES2104386T3/es not_active Expired - Lifetime
- 1994-03-14 AT AT94914706T patent/ATE154806T1/de not_active IP Right Cessation
- 1994-04-27 HR HR08/064,610A patent/HRP940271B1/xx not_active IP Right Cessation
- 1994-05-18 FI FI942313A patent/FI110781B/fi not_active IP Right Cessation
1997
- 1997-07-30 GR GR970401946T patent/GR3024297T3/el unknown

Also Published As

Publication number	Publication date
DE69403963T2 (de)	1997-11-20
HRP940271A2 (en)	1996-12-31
ES2104386T3 (es)	1997-10-01
US5686587A (en)	1997-11-11
WO1994026758A1 (en)	1994-11-24
DE69403963D1 (de)	1997-07-31
ATE154806T1 (de)	1997-07-15
CA2162401A1 (en)	1994-11-24
HRP940271B1 (en)	2000-02-29
FI942313L (fi)	1994-11-20
GR3024297T3 (en)	1997-10-31
JP2696608B2 (ja)	1998-01-14
EP0699207B1 (de)	1997-06-25
CA2162401C (en)	1998-11-03
EP0699207A1 (de)	1996-03-06
JPH08506596A (ja)	1996-07-16
FI110781B (fi)	2003-03-31
FI942313A0 (fi)	1994-05-18

Publication	Publication Date	Title
DK0699207T3 (da)	1997-12-08	Mellemprodukt til azithromycin
AU2534295A (en)	1995-12-21	Gastrin and cck antagonists
GB2270075B (en)	1995-01-04	Substituted 2-phenyl-3-methoxypropenoate fungicides
GR3033827T3 (en)	2000-10-31	New compounds and their compositions having anti-inflammatory and anti-thrombotic activities
TW263499B (de)	1995-11-21
PT687260E (pt)	2003-07-31	Processo para a preparacao de 9-desoxotaxanos
PH30476A (en)	1997-05-28	Risperidone pamoate
DE69428546D1 (en)	2001-11-08	3-acylaminobenzazepine
ZA961364B (en)	1996-08-22	1-Aryl-2-acylamino-ethane compounds
YU12000A (sh)	2002-11-15	Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova
AU6991696A (en)	1997-04-01	3-beta-aminoazabicyclo-octane or -nonane naphthamide derivatives as antipsychotic agents
ATE184305T1 (de)	1999-09-15	Monoazopigmente
TW344650B (en)	1998-11-11	Fungicidal compositions and the process for the preparation thereof
GB9410207D0 (en)	1994-07-06	Process
ATE247091T1 (de)	2003-08-15	Zwischenprodukte zur herstellung einer pharmazeutisch aktiven verbindung
IL126548A0 (en)	1999-08-17	Use of aspirochlorine or derivatives thereof as immunosuppressive agents