DK0708104T3 - Fremgangsmåde og mellemprodukt til fremstilling af terazosinhydrochloriddihydrat - Google Patents

Fremgangsmåde og mellemprodukt til fremstilling af terazosinhydrochloriddihydrat

Info

Publication number
DK0708104T3
DK0708104T3 DK95103188.9T DK95103188T DK0708104T3 DK 0708104 T3 DK0708104 T3 DK 0708104T3 DK 95103188 T DK95103188 T DK 95103188T DK 0708104 T3 DK0708104 T3 DK 0708104T3
Authority
DK
Denmark
Prior art keywords
tetrahydrofuroyl
dimethoxy
amino
preparation
hydrochloride dihydrate
Prior art date
Application number
DK95103188.9T
Other languages
English (en)
Inventor
Anthony Mannino
Wayne R Heitmann
Rodger F Henry
Bruce W Horrom
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23264439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0708104(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0708104T3 publication Critical patent/DK0708104T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95103188.9T 1994-10-18 1995-03-06 Fremgangsmåde og mellemprodukt til fremstilling af terazosinhydrochloriddihydrat DK0708104T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/324,635 US5504207A (en) 1994-10-18 1994-10-18 Process and intermediate for the preparation of terazosin hydrochloride dihydrate

Publications (1)

Publication Number Publication Date
DK0708104T3 true DK0708104T3 (da) 1997-03-10

Family

ID=23264439

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95103188.9T DK0708104T3 (da) 1994-10-18 1995-03-06 Fremgangsmåde og mellemprodukt til fremstilling af terazosinhydrochloriddihydrat

Country Status (11)

Country Link
US (1) US5504207A (da)
EP (1) EP0708104B1 (da)
JP (1) JP2711230B2 (da)
AT (1) ATE143959T1 (da)
BR (1) BR1100705A (da)
CA (1) CA2143971C (da)
DE (1) DE69500064T2 (da)
DK (1) DK0708104T3 (da)
ES (1) ES2089993T3 (da)
GR (2) GR960300047T1 (da)
HK (1) HK130297A (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587377A (en) * 1995-10-24 1996-12-24 Invamed, Inc. Terazosin crystalline polymorph and pharmaceutical compositions thereof
DE19546573A1 (de) * 1995-12-13 1997-06-19 Uetikon Chemie Gmbh Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung
US5952003A (en) * 1996-08-01 1999-09-14 Novartis Corporation Terazosin capsules
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
EP0849266B8 (de) * 1996-12-20 2007-10-03 Heumann PCS GmbH Neue polymorphe Form von Doxazosinmesylat (Form III)
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
US6248888B1 (en) * 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
US6200573B1 (en) 1999-12-03 2001-03-13 Starcor Pharmaceuticals, Inc. Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia
US20070161791A1 (en) * 2006-01-09 2007-07-12 Narsimha Reddy Penthala Process for the preparation of terazosin hydrocloride dihydrate
WO2008021891A2 (en) * 2006-08-08 2008-02-21 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
DE3683760D1 (de) * 1986-03-21 1992-03-12 Heumann Pharma Gmbh & Co Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
US5212176A (en) * 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
EP0497988A4 (en) * 1990-08-23 1993-03-10 Dainippon Ink And Chemicals, Inc. Antiviral agent
JP2652272B2 (ja) * 1990-12-31 1997-09-10 住化ファインケム株式会社 1−(4−アミノ−6,7−ジメトキシ−2−キナゾリニル)−4−(2−テトラヒドロフロイル)ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
US5294615A (en) * 1993-04-29 1994-03-15 Abbott Laboratories Terazosin polymorph and pharmaceutical composition

Also Published As

Publication number Publication date
EP0708104A1 (en) 1996-04-24
CA2143971A1 (en) 1996-04-19
DE69500064T2 (de) 1997-04-10
EP0708104B1 (en) 1996-10-09
JP2711230B2 (ja) 1998-02-10
ES2089993T3 (es) 1997-02-16
GR3021319T3 (en) 1997-01-31
HK130297A (en) 1997-09-19
ATE143959T1 (de) 1996-10-15
CA2143971C (en) 1997-06-03
ES2089993T1 (es) 1996-10-16
GR960300047T1 (en) 1996-08-31
BR1100705A (pt) 1999-10-13
DE69500064D1 (de) 1996-11-14
JPH08134066A (ja) 1996-05-28
US5504207A (en) 1996-04-02

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