DK0746556T3 - Tricycliske forbindelser med affinitet for 5-HT1A-receptoren - Google Patents

Tricycliske forbindelser med affinitet for 5-HT1A-receptoren

Info

Publication number
DK0746556T3
DK0746556T3 DK94930720T DK94930720T DK0746556T3 DK 0746556 T3 DK0746556 T3 DK 0746556T3 DK 94930720 T DK94930720 T DK 94930720T DK 94930720 T DK94930720 T DK 94930720T DK 0746556 T3 DK0746556 T3 DK 0746556T3
Authority
DK
Denmark
Prior art keywords
affinity
tricyclic compounds
ht1a receptor
ht1a
receptor
Prior art date
Application number
DK94930720T
Other languages
English (en)
Inventor
Allen B Reitz
Ellen W Baxter
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK0746556T3 publication Critical patent/DK0746556T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK94930720T 1993-10-25 1994-10-11 Tricycliske forbindelser med affinitet for 5-HT1A-receptoren DK0746556T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/142,748 US5512566A (en) 1993-10-25 1993-10-25 Tricyclic compounds having affinity for the 5-HT1A receptor
PCT/US1994/011544 WO1995011903A1 (en) 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor

Publications (1)

Publication Number Publication Date
DK0746556T3 true DK0746556T3 (da) 2002-12-16

Family

ID=22501119

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94930720T DK0746556T3 (da) 1993-10-25 1994-10-11 Tricycliske forbindelser med affinitet for 5-HT1A-receptoren

Country Status (15)

Country Link
US (1) US5512566A (da)
EP (1) EP0746556B1 (da)
JP (1) JP3709203B2 (da)
AT (1) ATE224895T1 (da)
AU (1) AU680562B2 (da)
CA (1) CA2174850A1 (da)
DE (1) DE69431441T2 (da)
DK (1) DK0746556T3 (da)
ES (1) ES2183843T3 (da)
IL (1) IL111246A (da)
NZ (1) NZ275689A (da)
PT (1) PT746556E (da)
SI (1) SI0746556T1 (da)
WO (1) WO1995011903A1 (da)
ZA (1) ZA948354B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755584A (en) * 1972-04-03 1973-08-28 Abbott Lab Tranquilizers
IT1052009B (it) * 1975-12-30 1981-06-20 Erba Carlo Spa Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati
JPH03502701A (ja) * 1988-12-15 1991-06-20 アボツト・ラボラトリーズ 5‐ht選択性物質
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
CA2073340C (en) * 1990-01-11 1997-05-20 Hakan Vilhelm Wikstrom Centrally acting 6,7,8,9-tetrahydro-3h-benz(e)indole heterocyclics
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics
JPH07500333A (ja) * 1991-10-24 1995-01-12 ジ・アップジョン・カンパニー ベンゾ−イソキノリン誘導体

Also Published As

Publication number Publication date
SI0746556T1 (en) 2003-02-28
EP0746556B1 (en) 2002-09-25
NZ275689A (en) 1997-12-19
AU680562B2 (en) 1997-07-31
ATE224895T1 (de) 2002-10-15
PT746556E (pt) 2002-12-31
CA2174850A1 (en) 1995-05-04
ZA948354B (en) 1996-04-24
JPH09504789A (ja) 1997-05-13
EP0746556A1 (en) 1996-12-11
ES2183843T3 (es) 2003-04-01
JP3709203B2 (ja) 2005-10-26
AU7975794A (en) 1995-05-22
DE69431441T2 (de) 2003-10-23
IL111246A (en) 1998-01-04
DE69431441D1 (de) 2002-10-31
IL111246A0 (en) 1994-12-29
US5512566A (en) 1996-04-30
WO1995011903A1 (en) 1995-05-04

Similar Documents

Publication Publication Date Title
PT885210E (pt) Compostos triciclicos que possuem afinidade de ligacao para receptores de melatonina sua producao e utilizacao
DK0640592T3 (da) N-acylerede tricycliske azaheteroringe anvendelige som vasopressin-antagonister
CO4700455A1 (es) Derivados tetraciclicos y proceso para su preparacion
NO970162L (no) Substituerte pyrimidinforbindelser og anvendelse derav
BR9305907A (pt) Uso de derivados de substituída para tratamento de esclerose múltipla
ES2113368T3 (es) Antagonistas de serotonina.
NO972726D0 (no) Tricykliske forbindelser
ES2093099T3 (es) Preparacion de piperidinas sustituidas.
ES2193241T3 (es) Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
FI942457A0 (fi) Substituoitujen piperidiinien valmistus
ATE196899T1 (de) N-(2,4-dioxo-2,3,4,5-tetrahydro-1h-1,5- benzodiazepin-3-yl)-3-amide
ES2194102T3 (es) Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
ATE109136T1 (de) Substituierte cyclohexene mit zentraler nervensystem-wirkung.
DK0746556T3 (da) Tricycliske forbindelser med affinitet for 5-HT1A-receptoren
ATE196508T1 (de) Enantiomere von cyclopenten-derivaten
DE69918046D1 (de) Neue basische Derivate von Benz(e)isoindol-1-onen und Pyrrolo(3,4-c)chinolin-1-onen mit 5-HT3-antagonistischer Aktivität, ihre Herstellung und ihre therapeutische Verwendung
GR82272B (da)
NO305556B1 (no) Tiokarbamoylforbindelser og anvendelse derav samt middel for beskyttelse av tekniske materialer
ES2004215A6 (es) Procedimiento para preparar quinazolinas tetraciclicas
DE69313931D1 (de) Polycyclische 31668P- und 31668U-Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als antibiotische oder antitumorale Arzneistoffe