DK0765876T3 - Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton - Google Patents

Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton

Info

Publication number: DK0765876T3
Authority: DK; Denmark
Prior art keywords: butyrolactone; gamma; beta; hydroxy; preparation
Prior art date: 1995-09-29

Application number

DK96111567T

Other languages

English (en)

Inventor

Fabio Giannessi

Angelis Francesco De

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-29

Filing date

1996-07-18

Publication date

1999-08-16

1996-07-18 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1999-08-16 Application granted granted Critical

1999-08-16 Publication of DK0765876T3 publication Critical patent/DK0765876T3/da

Links

FUDDLSHBRSNCBV-UHFFFAOYSA-N (+)-(R)-3-hydroxytetrahydrofuranone Natural products OC1COC(=O)C1 FUDDLSHBRSNCBV-UHFFFAOYSA-N 0.000 title abstract 2
FUDDLSHBRSNCBV-VKHMYHEASA-N (4s)-4-hydroxyoxolan-2-one Chemical compound O[C@@H]1COC(=O)C1 FUDDLSHBRSNCBV-VKHMYHEASA-N 0.000 title abstract 2
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
229960001518 levocarnitine Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Seasonings (AREA)

DK96111567T 1995-09-29 1996-07-18 Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton DK0765876T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT95RM000652A IT1276207B1 (it)	1995-09-29	1995-09-29	Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone

Publications (1)

Publication Number	Publication Date
DK0765876T3 true DK0765876T3 (da)	1999-08-16

Family

ID=11403592

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96111567T DK0765876T3 (da)	1995-09-29	1996-07-18	Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton

Country Status (12)

Country	Link
US (1)	US5714619A (da)
EP (1)	EP0765876B1 (da)
JP (1)	JP4012588B2 (da)
KR (1)	KR100407645B1 (da)
AT (1)	ATE174333T1 (da)
CA (1)	CA2181012A1 (da)
DE (1)	DE69601116T2 (da)
DK (1)	DK0765876T3 (da)
ES (1)	ES2126969T3 (da)
GR (1)	GR3029537T3 (da)
IT (1)	IT1276207B1 (da)
ZA (1)	ZA968127B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1297120B1 (it) *	1997-12-16	1999-08-03	Sigma Tau Ind Farmaceuti	Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
EP1055654B1 (en)	1998-12-11	2008-02-20	Daicel Chemical Industries, Ltd.	Process for the preparation of organic compounds with imide catalysts
KR20000065995A (ko) *	1999-04-12	2000-11-15	박영구	키랄 3-히드록시-γ-부티로락톤의 제조방법
CN104961711B (zh) *	2015-07-23	2017-03-08	沧州那瑞化学科技有限公司	（s）‑3‑羟基四氢呋喃和（r）‑3‑羟基四氢呋喃的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3087325B2 (ja) *	1991-02-21	2000-09-11	チッソ株式会社	光学活性化合物とその製造法
IT1256705B (it) *	1992-12-21	1995-12-12	Sigma Tau Ind Farmaceuti	Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
IT1261230B (it) *	1993-04-08	1996-05-09	Sigma Tau Ind Farmaceuti	Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
IT1261231B (it) *	1993-04-08	1996-05-09	Sigma Tau Ind Farmaceuti	Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
IT1261489B (it) *	1993-07-29	1996-05-23	Sigma Tau Ind Farmaceuti	Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
US5473104A (en) *	1994-09-13	1995-12-05	Neurocrine Biosciences, Inc.	Process for the preparation of L-carnitine

1995
- 1995-09-29 IT IT95RM000652A patent/IT1276207B1/it active IP Right Grant
1996
- 1996-07-11 CA CA002181012A patent/CA2181012A1/en not_active Abandoned
- 1996-07-11 US US08/678,684 patent/US5714619A/en not_active Expired - Fee Related
- 1996-07-18 ES ES96111567T patent/ES2126969T3/es not_active Expired - Lifetime
- 1996-07-18 DK DK96111567T patent/DK0765876T3/da active
- 1996-07-18 EP EP96111567A patent/EP0765876B1/en not_active Expired - Lifetime
- 1996-07-18 AT AT96111567T patent/ATE174333T1/de not_active IP Right Cessation
- 1996-07-18 DE DE69601116T patent/DE69601116T2/de not_active Expired - Fee Related
- 1996-07-23 KR KR1019960029667A patent/KR100407645B1/ko not_active Expired - Fee Related
- 1996-08-01 JP JP20355396A patent/JP4012588B2/ja not_active Expired - Fee Related
- 1996-09-27 ZA ZA968127A patent/ZA968127B/xx unknown
1999
- 1999-03-01 GR GR990400632T patent/GR3029537T3/el unknown

Also Published As

Publication number	Publication date
JP4012588B2 (ja)	2007-11-21
GR3029537T3 (en)	1999-06-30
EP0765876B1 (en)	1998-12-09
DE69601116T2 (de)	1999-05-06
KR970015583A (ko)	1997-04-28
ITRM950652A1 (it)	1997-03-29
ZA968127B (en)	1997-04-21
CA2181012A1 (en)	1997-03-30
DE69601116D1 (de)	1999-01-21
EP0765876A1 (en)	1997-04-02
JPH09110851A (ja)	1997-04-28
ES2126969T3 (es)	1999-04-01
IT1276207B1 (it)	1997-10-27
ITRM950652A0 (da)	1995-09-29
ATE174333T1 (de)	1998-12-15
KR100407645B1 (ko)	2004-03-18
US5714619A (en)	1998-02-03

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