DK0776202T3 - Liposomalt indkapslet taxol, dets fremstilling af dets anvendelse - Google Patents

Liposomalt indkapslet taxol, dets fremstilling af dets anvendelse

Info

Publication number: DK0776202T3
Authority: DK; Denmark
Prior art keywords: taxol; pct; preparation; sec; encapsulated taxol
Prior art date: 1994-08-20

Application number

DK95929002T

Other languages

Danish (da)

English (en)

Inventor

Iduna Fichtner

Regine Reszka

Martin Brandl

Gernot Warnke

Original Assignee

Max Delbrueck Centrum

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-20

Filing date

1995-08-18

Publication date

2000-11-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6526804&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0776202(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-08-18 Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum

2000-11-13 Application granted granted Critical

2000-11-13 Publication of DK0776202T3 publication Critical patent/DK0776202T3/da

Links

229930012538 Paclitaxel Natural products 0.000 title abstract 5
229960001592 paclitaxel Drugs 0.000 title abstract 5
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 5
206010028980 Neoplasm Diseases 0.000 abstract 1
239000000443 aerosol Substances 0.000 abstract 1
238000005538 encapsulation Methods 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
238000000265 homogenisation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dispersion Chemistry (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Epoxy Compounds (AREA)
Fats And Perfumes (AREA)

DK95929002T 1994-08-20 1995-08-18 Liposomalt indkapslet taxol, dets fremstilling af dets anvendelse DK0776202T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4430593A DE4430593C2 (de)	1994-08-20	1994-08-20	Verfahren zur Herstellung von Liposomal verkapseltem Taxol
PCT/DE1995/001163 WO1996005821A1 (fr)	1994-08-20	1995-08-18	Taxol encapsule dans des preparations liposomales, sa preparation et son utilisation

Publications (1)

Publication Number	Publication Date
DK0776202T3 true DK0776202T3 (da)	2000-11-13

Family

ID=6526804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95929002T DK0776202T3 (da)	1994-08-20	1995-08-18	Liposomalt indkapslet taxol, dets fremstilling af dets anvendelse

Country Status (7)

Country	Link
US (1)	US6090955A (fr)
EP (1)	EP0776202B1 (fr)
AT (1)	ATE192924T1 (fr)
DE (3)	DE4430593C2 (fr)
DK (1)	DK0776202T3 (fr)
GR (1)	GR3034162T3 (fr)
WO (1)	WO1996005821A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0964676A1 (fr) *	1997-01-30	1999-12-22	Quadrant Healthcare (UK) Limited	Microparticules et leur utilisation dans le traitement du cancer
IT1289939B1 (it) *	1997-02-20	1998-10-19	Angelini Ricerche Spa	Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua
US7348025B2 (en)	1997-09-23	2008-03-25	Research Development Foundation	Small particle liposome aerosols for delivery of anticancer drugs
US6090407A (en) *	1997-09-23	2000-07-18	Research Development Foundation	Small particle liposome aerosols for delivery of anti-cancer drugs
US6787132B1 (en)	1997-12-04	2004-09-07	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Combined chemo-immunotherapy with liposomal drugs and cytokines
EP1033971B1 (fr) *	1997-12-04	2009-09-09	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Traitement chimio et immunotherapeutique combine a l'aide de medicaments et de cytokines encapsules dans des liposomes
US6146659A (en) *	1998-07-01	2000-11-14	Neopharm, Inc.	Method of administering liposomal encapsulated taxane
US6461637B1 (en) *	2000-09-01	2002-10-08	Neopharm, Inc.	Method of administering liposomal encapsulated taxane
US7314637B1 (en)	1999-06-29	2008-01-01	Neopharm, Inc.	Method of administering liposomal encapsulated taxane
US7556827B1 (en)	1999-08-06	2009-07-07	Max-Delbrück-Centrum-für Molekulare Medizin	Implantable active ingredient depot
FR2797874B1 (fr) *	1999-08-27	2002-03-29	Adir	Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1116875C (zh) *	2000-10-19	2003-08-06	南京振中生物工程有限公司	紫杉醇脂质组合物及其制备方法
AU2002228772B2 (en)	2000-11-02	2005-12-08	Sloan Kettering Institute For Cancer Research	Methods for enhancing the efficacy of cytotoxic agents through the use of HSP90 inhibitors
US7115565B2 (en)	2001-01-18	2006-10-03	Pharmacia & Upjohn Company	Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
DE10154464B4 (de) *	2001-11-08	2005-10-20	Max Delbrueck Centrum	Oral verabreichbare pharmazeutische Zubereitung umfassend liposomal verkapseltes Taxol
EP1506032A1 (fr) *	2002-05-20	2005-02-16	Research Development Foundation	Medicament de type aerosol pour l'inhibition de metastases pulmonaires
EP1530465B2 (fr) *	2002-06-26	2015-12-16	MediGene AG	Procede de production d'une preparation liposomale cationique contenant un compose lipophile
US20040034336A1 (en) *	2002-08-08	2004-02-19	Neal Scott	Charged liposomes/micelles with encapsulted medical compounds
JP2006508912A (ja) *	2002-08-23	2006-03-16	メディゲーネオンコロギーゲゼルシャフトミットベシュレンクテルハフツング	非小胞性カチオン脂質調製物
BRPI0407096A (pt) *	2003-02-03	2006-01-24	Neopharm Inc	Taxano encapsulado em lipossomo estável, estéril e filtrável e outros fármacos antineoplásicos
US7517342B2 (en) *	2003-04-29	2009-04-14	Boston Scientific Scimed, Inc.	Polymer coated device for electrically medicated drug delivery
EP1643971A2 (fr) *	2003-05-22	2006-04-12	Neopharm, Inc.	Formulations liposomales combinees
WO2005039533A1 (fr) *	2003-10-15	2005-05-06	Medigene Ag	Procede d'administration de liposomes cationiques comprenant un medicament actif
EP1896007B1 (fr)	2005-05-04	2014-03-19	Medigene AG	Methode d'administration d'une preparation liposomale cationique contenant du paclitaxel
PL1888033T3 (pl) *	2005-06-09	2014-09-30	Meda Ab	Sposób i kompozycja do leczenia chorób zapalnych
DE102005043706B4 (de) *	2005-07-02	2011-12-01	Daimler Ag	Rückhaltesystem
PL1919450T3 (pl) *	2005-09-01	2014-11-28	Meda Ab	Kompozycja liposomowa zawierająca lek przeciwhistaminowy i kortykosteroid oraz jej zastosowanie do wytwarzania leku do leczenia nieżytu nosa i chorób spokrewnionych
BRPI0709075A2 (pt)	2006-03-20	2011-10-11	Medigene Ag	tratamento de cáncer de mama triplo receptor negativo
US20080108707A1 (en) *	2006-11-02	2008-05-08	Arbiser Jack L	Antiangiogenic, antitumor, chemopreventative agents
TWI438009B (zh) *	2010-02-19	2014-05-21	Teikoku Pharma Usa Inc	紫杉烷前－乳劑調配物及其製造與使用之方法
US10842770B2 (en)	2010-05-03	2020-11-24	Teikoku Pharma Usa, Inc.	Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
US9066974B1 (en) *	2010-11-13	2015-06-30	Sirbal Ltd.	Molecular and herbal combinations for treating psoriasis
US9095606B1 (en)	2010-11-13	2015-08-04	Sirbal Ltd.	Molecular and herbal combinations for treating psoriasis
JO3685B1 (ar)	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN112656764B (zh) *	2020-12-28	2022-09-02	吉林大学	一种紫杉醇铂类共载靶向长循环脂质体及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE194767T1 (de) *	1992-03-23	2000-08-15	Univ Georgetown	In liposomen verkapseltes taxol und verwendungsverfahren
AU4633893A (en) *	1992-06-17	1994-01-04	University Of Massachusetts Medical Center	Liposomal formulations for administering to cancer patients
WO1994026254A1 (fr) *	1993-05-17	1994-11-24	The Liposome Company, Inc.	Incorporation de taxol dans des liposomes et des gels
US5415869A (en) *	1993-11-12	1995-05-16	The Research Foundation Of State University Of New York	Taxol formulation

1994
- 1994-08-20 DE DE4430593A patent/DE4430593C2/de not_active Expired - Lifetime
- 1994-08-20 DE DE4447770A patent/DE4447770C2/de not_active Expired - Lifetime
1995
- 1995-08-18 WO PCT/DE1995/001163 patent/WO1996005821A1/fr not_active Ceased
- 1995-08-18 EP EP95929002A patent/EP0776202B1/fr not_active Revoked
- 1995-08-18 AT AT95929002T patent/ATE192924T1/de not_active IP Right Cessation
- 1995-08-18 DE DE59508360T patent/DE59508360D1/de not_active Revoked
- 1995-08-18 US US08/793,238 patent/US6090955A/en not_active Expired - Lifetime
- 1995-08-18 DK DK95929002T patent/DK0776202T3/da active
2000
- 2000-08-09 GR GR20000401857T patent/GR3034162T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
US6090955A (en)	2000-07-18
DE4430593C2 (de)	1999-01-14
EP0776202B1 (fr)	2000-05-17
DE4447770C2 (de)	2002-12-19
DE59508360D1 (de)	2000-06-21
GR3034162T3 (en)	2000-11-30
EP0776202A1 (fr)	1997-06-04
DE4430593A1 (de)	1996-02-22
ATE192924T1 (de)	2000-06-15
WO1996005821A1 (fr)	1996-02-29

Publication	Publication Date	Title
DK0776202T3 (da)	2000-11-13	Liposomalt indkapslet taxol, dets fremstilling af dets anvendelse
SE9404196D0 (sv)	1994-12-02	New antithrombotic formulation
ATE257386T1 (de)	2004-01-15	Pharmazeutische zusammensetzungen enthaltend eine mischung von selbstvernetzter und nichtselbstvernetzter hyaluronsäure zur behandlung von arthropathien
DE60126980D1 (de)	2007-04-12	Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen
AR052921A1 (es)	2007-04-11	Uso de ranolazina para la preparacion de una composicion farmaceutica y composicion farmaceutica
DE69738000D1 (de)	2007-09-20	Neue Arzneiformulierung enthaltend Budesonide
ID29393A (id)	2001-08-30	Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
SE9401406D0 (sv)	1994-04-25	Pharmaceutical products for curing tumourous diseases and process for preparing same
ATE267798T1 (de)	2004-06-15	Kombinierte wirkstoffe als methode zur gezielten wirkstoff-freisetzung
DE69008476D1 (de)	1994-06-01	Pharmazeutische Zusammensetzung zur Behandlung von Osteoporose.
DE60115842D1 (de)	2006-01-19	Ventilanordnung
TR199701584T1 (xx)	1999-03-22	Anestezi etkili yeni farmas�tik kompozisyon
ATE190225T1 (de)	2000-03-15	Arzneiform zur abgabe von wirkstoffen an wunden
PT1001775E (pt)	2002-07-31	Medicamento contendo ioimbina e arginina para tratamento de disfuncao erectil
DE3582594D1 (de)	1991-05-23	Proglumid und dessen pharmazeutische zusammensetzungen zur anwendung bei der behandlung von neoplastischen affektionen.
EP1037918A4 (fr)	2004-11-03	Procede et composition pour ameliorer l'efficacite d'un vaccin
JO3446B1 (ar)	2020-07-05	طريقة لمعالجة الأرق الأولي
ATE110269T1 (de)	1994-09-15	Ipriflavone enthaltende pharmazeutische zubereitungen, verfahren zur herstellung und therapeutische verwendung.
DE69924483D1 (de)	2005-05-04	Kombinationstherapie zur behandlung von tumoren
ATE215367T1 (de)	2002-04-15	Nimesulid enthaltende pharmazeutische zubereitung zur topischen anwendung
ATE261732T1 (de)	2004-04-15	Pharmazeutische zusammensetzung, umfassend eukalyptus- und orangenöl
HUT77175A (hu)	1998-03-02	Szelegilin alkalmazása epilepsziás betegségek kezelésére használható gyógyszerkészítmények előállítására és szelegilint tartalmazó epilepsziaellenes gyógyszerkészítmények
ATE211650T1 (de)	2002-01-15	Verwendung von topische präparationen mit glyceryl trinitrat und lanolin zur behandlung von erektilen funktionsstörungen
DE59101818D1 (de)	1994-07-14	Arzneimittelzubereitung, enthaltend Stigmasta-4-en-3-on sowie deren Verwendung.
ATE200624T1 (de)	2001-05-15	Verwendung von 4'-iodo - 4 - deoxydoxorubicin zur behandlung von amyloidosis