DK0804411T3 - Syntetiske polyumættede fedtsyreanaloger - Google Patents

Syntetiske polyumættede fedtsyreanaloger

Info

Publication number: DK0804411T3
Authority: DK; Denmark
Prior art keywords: acid; pct; polyunsaturated fatty; glycine; fatty acid
Prior art date: 1994-10-26

Application number

DK95935757T

Other languages

English (en)

Inventor

Merilyn Joy Sleigh

Paul Adam Schober

Antonio Ferrante

Alfred Poulos

Deborah Ann Rathjen

Fred Widmer

Original Assignee

Womens & Childrens Hospital

Peptech Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-26

Filing date

1995-10-25

Publication date

2003-11-24

1995-10-25 Application filed by Womens & Childrens Hospital, Peptech Ltd filed Critical Womens & Childrens Hospital

2003-11-24 Application granted granted Critical

2003-11-24 Publication of DK0804411T3 publication Critical patent/DK0804411T3/da

Links

235000020777 polyunsaturated fatty acids Nutrition 0.000 title abstract 3
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
239000004471 Glycine Substances 0.000 abstract 2
235000001014 amino acid Nutrition 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
WIOJZOOPDOZCLL-TZGPHXOASA-N (2S)-2-aminobutanedioic acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O.CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O WIOJZOOPDOZCLL-TZGPHXOASA-N 0.000 abstract 1
SUHOKBYLJMPHSL-LXPGDDCISA-N CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.OC(=O)[C@@H](N)CC(O)=O Chemical compound CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.CCCC=CC(O)=O.OC(=O)[C@@H](N)CC(O)=O SUHOKBYLJMPHSL-LXPGDDCISA-N 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
QJCXFEFENFYDNE-IFNWOZJISA-N NCC(O)=O.CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O Chemical compound NCC(O)=O.CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O QJCXFEFENFYDNE-IFNWOZJISA-N 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000000078 anti-malarial effect Effects 0.000 abstract 1
239000003430 antimalarial agent Substances 0.000 abstract 1
235000003704 aspartic acid Nutrition 0.000 abstract 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
125000002843 carboxylic acid group Chemical group 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
210000000440 neutrophil Anatomy 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/49—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Fats And Perfumes (AREA)
Polyamides (AREA)
Peptides Or Proteins (AREA)

DK95935757T 1994-10-26 1995-10-25 Syntetiske polyumættede fedtsyreanaloger DK0804411T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AUPM9065A AUPM906594A0 (en)	1994-10-26	1994-10-26	Synthetic polyunsaturated fatty acid analogues
PCT/AU1995/000717 WO1996013507A1 (en)	1994-10-26	1995-10-25	Synthetic polyunsaturated fatty acid analogues

Publications (1)

Publication Number	Publication Date
DK0804411T3 true DK0804411T3 (da)	2003-11-24

Family

ID=3783583

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95935757T DK0804411T3 (da)	1994-10-26	1995-10-25	Syntetiske polyumættede fedtsyreanaloger

Country Status (12)

Country	Link
US (1)	US5998476A (da)
EP (1)	EP0804411B1 (da)
JP (1)	JPH10508011A (da)
KR (1)	KR100382159B1 (da)
CN (1)	CN1109016C (da)
AT (1)	ATE245626T1 (da)
AU (1)	AUPM906594A0 (da)
DE (1)	DE69531359T2 (da)
DK (1)	DK0804411T3 (da)
ES (1)	ES2203646T3 (da)
PT (1)	PT804411E (da)
WO (1)	WO1996013507A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997038688A1 (en)	1996-04-12	1997-10-23	Peptide Technology Pty. Limited	Methods of treating immunopathologies using polyunsaturated fattyacids
US6426367B1 (en) *	1999-09-09	2002-07-30	Efa Sciences Llc	Methods for selectively occluding blood supplies to neoplasias
AU784116B2 (en) *	1999-09-17	2006-02-09	Peplin Biolipids Pty Ltd	Anti-cancer nitro- and thia-fatty acids
AUPQ291499A0 (en) *	1999-09-17	1999-10-07	Women's And Children's Hospital Adelaide	Novel nitro and sulphur containing compounds
GB0016045D0 (en) *	2000-06-29	2000-08-23	Laxdale Limited	Therapeutic combinations of fatty acids
WO2003007876A2 (en) *	2001-06-25	2003-01-30	University Of Massachusetts	N-fatty acid-amino acid conjugates and therapeutic uses
KR100477681B1 (ko) *	2002-11-20	2005-03-21	삼성전자주식회사	화상형성장치
CA2436650A1 (en)	2003-08-06	2005-02-06	Naturia Inc.	Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses
DE10351111A1 (de) *	2003-11-03	2005-06-16	Langlotz, Rainer	Arzneimittel und Verfahren zu ihrer Herstellung
US20090215895A1 (en) *	2004-01-30	2009-08-27	Peplin Biolipids Pty Ltd	Therapeutic and carrier molecules
US7544714B2 (en) *	2004-07-16	2009-06-09	University Of Massachusetts	Lipid-amino acid conjugates and methods of use
WO2009006668A1 (en) *	2007-02-05	2009-01-15	Children, Youth And Women's Health Service	Modulators of antigen-dependent t cell proliferation
US20120028335A1 (en)	2010-07-28	2012-02-02	Life Technologies Corporation	Anti-viral azide-containing compounds
US9144575B2 (en)	2010-07-28	2015-09-29	Life Technologies Corporation	Anti-viral azide containing compounds
WO2016130417A1 (en) *	2015-02-11	2016-08-18	Omthera Pharmaceuticals Inc	Omega-3 fatty acid prodrug compounds and uses thereof
NZ735250A (en)	2015-07-08	2020-08-28	Research & Business Found Sungkyunkwan Univ	Pyrrolidine carboxamido derivatives and methods for preparing and using the same
US11690825B2 (en)	2016-03-09	2023-07-04	Board Of Regents, The University Of Texas System	20-HETE receptor (GPR75) antagonists and methods of use
EP3759070A4 (en)	2018-02-28	2021-12-08	Bridge Biotherapeutics, Inc.	WATER-SOLUBLE SALTS OF LIPID PEPTIDES AND THEIR PREPARATION AND USE PROCESSES
US20230065371A1 (en) *	2020-01-30	2023-03-02	Silicycle Inc.	Process for manufacturing solid neutral amino acid salts of polyunsaturated fatty acids

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4939174A (en) *	1988-02-26	1990-07-03	Shashoua Victor E	Appetite suppression with dopamine-fatty acid conjugates
HU209973B (en) *	1988-03-09	1995-01-30	Biorex Kutato Fejlesztoe Kft	Process for production of antiviral and immunstimular pharmaceutical composition
HU199775B (en) *	1988-03-09	1990-03-28	Nagy Peter Literati	Process for production of formed by fatty acids salts of amin acids and medical compositions containing them
ES2052066T3 (es) *	1988-10-31	1994-07-01	Sandoz Nutrition Ltd	Mejoras en o relacionadas con compuestos organicos.
HU207287B (en) *	1989-01-17	1993-03-29	Biosignal Kutato Fejlesztoe Kf	Polyene fatty acid derivatives of tyrozine-quinaze inhibiting activity and pharmaceutical composition containing them as active component
JPH02225411A (ja) *	1989-02-28	1990-09-07	Nippon Oil & Fats Co Ltd	高度不飽和脂肪酸の溶血性低下方法
JPH03236315A (ja) *	1989-12-05	1991-10-22	Nippon Oil & Fats Co Ltd	抗精神病薬
JPH06511479A (ja) *	1991-06-24	1994-12-22	ウィメンズ　アンド　チルドレンズ　ホスピタル	マラリアおよびその他の疾患を治療するための方法および組成物
US5807884A (en) *	1992-10-30	1998-09-15	Emory University	Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5767156A (en) *	1993-10-06	1998-06-16	Peptide Technology Limited	Polyunsaturated fatty acids and uses thereof
IT1264987B1 (it) *	1993-12-14	1996-10-17	Prospa Bv	Sali di un acido grasso poliinsaturo e formulazioni farmaceutiche che li contengono
EP0689835A3 (en) *	1994-06-30	1996-04-17	Ajinomoto Kk	Composition containing an amino acid mixture and at least one N-3 fatty acid

1994
- 1994-10-26 AU AUPM9065A patent/AUPM906594A0/en not_active Abandoned
1995
- 1995-10-25 WO PCT/AU1995/000717 patent/WO1996013507A1/en not_active Ceased
- 1995-10-25 KR KR1019970702725A patent/KR100382159B1/ko not_active Expired - Fee Related
- 1995-10-25 ES ES95935757T patent/ES2203646T3/es not_active Expired - Lifetime
- 1995-10-25 CN CN95195864A patent/CN1109016C/zh not_active Expired - Fee Related
- 1995-10-25 DK DK95935757T patent/DK0804411T3/da active
- 1995-10-25 PT PT95935757T patent/PT804411E/pt unknown
- 1995-10-25 US US08/836,164 patent/US5998476A/en not_active Expired - Fee Related
- 1995-10-25 DE DE69531359T patent/DE69531359T2/de not_active Expired - Fee Related
- 1995-10-25 EP EP95935757A patent/EP0804411B1/en not_active Expired - Lifetime
- 1995-10-25 AT AT95935757T patent/ATE245626T1/de not_active IP Right Cessation
- 1995-10-25 JP JP8514187A patent/JPH10508011A/ja not_active Ceased

Also Published As

Publication number	Publication date
EP0804411A4 (en)	1999-06-16
KR970707074A (ko)	1997-12-01
ES2203646T3 (es)	2004-04-16
JPH10508011A (ja)	1998-08-04
DE69531359D1 (de)	2003-08-28
CN1167481A (zh)	1997-12-10
EP0804411A1 (en)	1997-11-05
KR100382159B1 (ko)	2004-11-16
PT804411E (pt)	2003-12-31
EP0804411B1 (en)	2003-07-23
WO1996013507A1 (en)	1996-05-09
ATE245626T1 (de)	2003-08-15
US5998476A (en)	1999-12-07
AUPM906594A0 (en)	1994-11-17
DE69531359T2 (de)	2004-04-22
CN1109016C (zh)	2003-05-21

Publication	Publication Date	Title
DK0804411T3 (da)	2003-11-24	Syntetiske polyumættede fedtsyreanaloger
ATE239717T1 (de)	2003-05-15	Ester und amide von nicht-steroidalen entzündungs-hemmenden carbonsäuren die als anti-oxidantien 5- lipoxygenase-hemmer und nicht-steroidale entzündungs-hemmende mittel verwendet werden können
CY1105119T1 (el)	2009-11-04	Χρηση πολυακορεστων λιπαρων οξεων για την πρωτογενη προληψη σοβαρων καρδιαγγειακων επεισοδιων
HUP0004230A2 (hu)	2001-06-28	Probucol monoésztereinek alkalmazása VCAM-1 gátlására alkalmas gyógyászati készítmények előállítására
ATE218336T1 (de)	2002-06-15	Verwendung von 3-benzoylphenylessigsäuren, deren estern oder amiden zur behandlung von glc1a glaukom
PT774962E (pt)	2004-09-30	Utilizacao de dha como uma composicao farmaceutica
DE69524639D1 (de)	2002-01-24	Modifizierte mehrfach ungesättigte fettsäuren
MY109928A (en)	1997-09-30	Fatty acid treatment
BR9508298A (pt)	1998-11-03	Inibidores de indolizina de spla2
DE69841574D1 (de)	2010-05-06	Gaba-analoga zur verhütung und behandlung gastrointestinaler beschwerden
CY1106085T1 (el)	2011-06-08	Το ανθρωπινο γονιδιο της δελτα-5δεσατουρασης και οι χρησεις του
ATE201013T1 (de)	2001-05-15	Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen
DK1138325T3 (da)	2003-10-13	Anvendelse af syntetiske triglycerider på basis af konjugeret linolsyre til fremstilling af midler til støtte for tumorbehandlingen
NO20000689L (no)	2000-04-11	FremgangsmÕte for Õ øke inkorporasjonseffektivitet av <omega>- 3-høyt umettede fettsyrer i fjærkrekjøtt
AU1852083A (en)	1984-03-08	Arachidonic acid analogues
ES2045120T3 (es)	1994-01-16	Metodo para preparar un medicamento para el tratamiento o la prevencion de la perdida de memoria.
EP1037624A4 (en)	2002-05-15	DIABETES TREATMENT METHODS AND COMPOSITIONS
ATE270100T1 (de)	2004-07-15	Ibuprofenthioester als hemmer der nf-kappa b abhängigen bildung von mediatoren von entzündung und schmerz
ATE60508T1 (de)	1991-02-15	Eisen enthaltende zusammensetzung und verfahren zur behandlung von krebs.
ATE164518T1 (de)	1998-04-15	Verwendung von fettsäuren zur behandlung von abnormalen verkalkung des gewebes
NZ304924A (en)	2000-05-26	hybridised triglycerides
ATE261989T1 (de)	2004-04-15	Dhc-peptid und dieses enthaltendes mittel
DE60329588D1 (de)	2009-11-19	Verwendung von epa and dha zur sekundären prevention von schlaganfällen
EE200000227A (et)	2001-06-15	Meetod konjugeeritud linoolhappe kontsentratsiooni tõstmiseks mäletseja piima- ja/või koerasvas
AR010461A2 (es)	2000-06-28	Derivados de ciclopropano utiles como intermediarios para la preparacion de acidos ciclopropano carboxilicos