DK0805628T3 - Receptor specifik transepitheltransport af immunogener - Google Patents
Receptor specifik transepitheltransport af immunogenerInfo
- Publication number
- DK0805628T3 DK0805628T3 DK96903522T DK96903522T DK0805628T3 DK 0805628 T3 DK0805628 T3 DK 0805628T3 DK 96903522 T DK96903522 T DK 96903522T DK 96903522 T DK96903522 T DK 96903522T DK 0805628 T3 DK0805628 T3 DK 0805628T3
- Authority
- DK
- Denmark
- Prior art keywords
- antigen
- immunogens
- receptor specific
- transepithelial transport
- immune response
- Prior art date
Links
- 230000018889 transepithelial transport Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 230000028993 immune response Effects 0.000 abstract 2
- 210000000987 immune system Anatomy 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 abstract 1
- 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000013566 allergen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/374,159 US6086875A (en) | 1995-01-17 | 1995-01-17 | Receptor specific transepithelial transport of immunogens |
| US57817195A | 1995-12-29 | 1995-12-29 | |
| PCT/US1996/000597 WO1996022024A1 (en) | 1995-01-17 | 1996-01-17 | Receptor specific transepithelial transport of immunogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0805628T3 true DK0805628T3 (da) | 2003-07-14 |
Family
ID=27006452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96903522T DK0805628T3 (da) | 1995-01-17 | 1996-01-17 | Receptor specifik transepitheltransport af immunogener |
| DK03004479T DK1323346T3 (da) | 1995-01-17 | 1996-01-17 | Receptorspecifik transport af immunogener gennem epitelet |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03004479T DK1323346T3 (da) | 1995-01-17 | 1996-01-17 | Receptorspecifik transport af immunogener gennem epitelet |
Country Status (9)
| Country | Link |
|---|---|
| EP (3) | EP1658772A3 (da) |
| JP (2) | JP4026848B2 (da) |
| AT (2) | ATE238668T1 (da) |
| CA (1) | CA2210656C (da) |
| DE (2) | DE69627820T2 (da) |
| DK (2) | DK0805628T3 (da) |
| ES (2) | ES2194973T3 (da) |
| PT (1) | PT1323346E (da) |
| WO (1) | WO1996022024A1 (da) |
Families Citing this family (142)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030613A (en) * | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US6485726B1 (en) | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US6086875A (en) * | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| IT1289608B1 (it) * | 1997-02-05 | 1998-10-15 | Angelini Ricerche Spa | Composizione per uso terapeutico o diagnostico somministrabile per via intranasale,sublinguale o vaginale |
| CA2399561A1 (en) * | 2000-02-03 | 2001-08-09 | Lennart Hammarstrom | Ruminant mhc class i-like fc receptors |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| AU2001268427B2 (en) | 2000-06-16 | 2007-03-29 | Glaxosmithkline Intellectual Property Limited | Antibodies that immunospecifically bind to blys |
| EP1355919B1 (en) | 2000-12-12 | 2010-11-24 | MedImmune, LLC | Molecules with extended half-lives, compositions and uses thereof |
| EP1683865A3 (en) | 2001-02-02 | 2006-10-25 | Eli Lilly & Company | Mammalian proteins and in particular CD200 |
| WO2002064612A2 (en) | 2001-02-09 | 2002-08-22 | Human Genome Sciences, Inc. | Human g-protein chemokine receptor (ccr5) hdgnr10 |
| JP2004536579A (ja) | 2001-04-13 | 2004-12-09 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 血管内皮増殖因子2 |
| JP4538192B2 (ja) * | 2001-05-01 | 2010-09-08 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 免疫疾患を治療するための融合分子及び方法 |
| US7265208B2 (en) | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| US8093357B2 (en) | 2002-03-01 | 2012-01-10 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
| US8188231B2 (en) | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
| CA2479212A1 (en) * | 2002-03-15 | 2003-09-25 | Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| EP2270049A3 (en) | 2002-04-12 | 2011-03-09 | Medimmune, Inc. | Recombinant anti-interleukin-9-antibody |
| AT502293B1 (de) * | 2002-05-15 | 2008-03-15 | Igeneon Krebs Immuntherapie | Immunogener, monoklonaler antikörper |
| CA2491129A1 (en) * | 2002-07-03 | 2004-01-15 | Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| EP1923464A1 (en) | 2002-08-30 | 2008-05-21 | Japan Science and Technology Agency | Ligase of a hyperthermostable bacterium and chip using the same |
| AU2004206250B8 (en) | 2003-01-21 | 2009-09-17 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel acyl coenzyme a, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof |
| US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
| US8084582B2 (en) | 2003-03-03 | 2011-12-27 | Xencor, Inc. | Optimized anti-CD20 monoclonal antibodies having Fc variants |
| US8388955B2 (en) | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
| KR101224235B1 (ko) | 2003-04-11 | 2013-01-25 | 메디뮨 엘엘씨 | 재조합 il9 항체 및 그의 용도 |
| US9051373B2 (en) | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
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| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
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| US5349053A (en) * | 1990-06-01 | 1994-09-20 | Protein Design Labs, Inc. | Chimeric ligand/immunoglobulin molecules and their uses |
| EP0464533B1 (de) * | 1990-06-28 | 1998-07-29 | Hoechst Aktiengesellschaft | Fusionsproteine mit immunglobulinanteilen, ihre Herstellung und Verwendung |
| AU3937693A (en) * | 1992-04-10 | 1993-11-18 | Brigham And Women's Hospital | Methods and compositions for oral delivery of therapeutic agents |
| DE69418699T2 (de) * | 1993-01-11 | 1999-09-30 | Dana-Farber Cancer Institute, Boston | Induktion der antworten zytotoxischer t-lymphozyten |
| US5698679A (en) * | 1994-09-19 | 1997-12-16 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for targeting an immune response |
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1996
- 1996-01-17 EP EP05112065A patent/EP1658772A3/en not_active Withdrawn
- 1996-01-17 AT AT96903522T patent/ATE238668T1/de not_active IP Right Cessation
- 1996-01-17 AT AT03004479T patent/ATE331438T1/de active
- 1996-01-17 EP EP96903522A patent/EP0805628B1/en not_active Expired - Lifetime
- 1996-01-17 DE DE69627820T patent/DE69627820T2/de not_active Expired - Lifetime
- 1996-01-17 ES ES96903522T patent/ES2194973T3/es not_active Expired - Lifetime
- 1996-01-17 PT PT03004479T patent/PT1323346E/pt unknown
- 1996-01-17 DK DK96903522T patent/DK0805628T3/da active
- 1996-01-17 DE DE69636312T patent/DE69636312T2/de not_active Expired - Lifetime
- 1996-01-17 ES ES03004479T patent/ES2268182T3/es not_active Expired - Lifetime
- 1996-01-17 EP EP03004479A patent/EP1323346B1/en not_active Expired - Lifetime
- 1996-01-17 CA CA2210656A patent/CA2210656C/en not_active Expired - Lifetime
- 1996-01-17 JP JP52235696A patent/JP4026848B2/ja not_active Expired - Lifetime
- 1996-01-17 WO PCT/US1996/000597 patent/WO1996022024A1/en not_active Ceased
- 1996-01-17 DK DK03004479T patent/DK1323346T3/da active
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2007
- 2007-08-01 JP JP2007200621A patent/JP2008007513A/ja active Pending
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| DE69627820T2 (de) | 2004-04-08 |
| EP1323346B1 (en) | 2006-06-28 |
| JP2002515850A (ja) | 2002-05-28 |
| DK1323346T3 (da) | 2006-10-30 |
| EP1658772A2 (en) | 2006-05-24 |
| CA2210656C (en) | 2011-07-05 |
| EP0805628A4 (en) | 1999-03-24 |
| JP2008007513A (ja) | 2008-01-17 |
| CA2210656A1 (en) | 1996-07-25 |
| EP0805628A1 (en) | 1997-11-12 |
| ATE331438T1 (de) | 2006-07-15 |
| EP0805628B1 (en) | 2003-05-02 |
| PT1323346E (pt) | 2006-10-31 |
| EP1323346A2 (en) | 2003-07-02 |
| JP4026848B2 (ja) | 2007-12-26 |
| DE69636312D1 (de) | 2006-08-10 |
| DE69636312T2 (de) | 2007-06-06 |
| ES2268182T3 (es) | 2007-03-16 |
| DE69627820D1 (de) | 2003-06-05 |
| EP1658772A3 (en) | 2007-01-17 |
| WO1996022024A1 (en) | 1996-07-25 |
| EP1323346A3 (en) | 2003-11-26 |
| ES2194973T3 (es) | 2003-12-01 |
| ATE238668T1 (de) | 2003-05-15 |
| EP1658772A8 (en) | 2007-01-10 |
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