DK0811063T3 - Kemokin-receptor 88C og dens antistoffer - Google Patents

Kemokin-receptor 88C og dens antistoffer

Info

Publication number
DK0811063T3
DK0811063T3 DK96945669T DK96945669T DK0811063T3 DK 0811063 T3 DK0811063 T3 DK 0811063T3 DK 96945669 T DK96945669 T DK 96945669T DK 96945669 T DK96945669 T DK 96945669T DK 0811063 T3 DK0811063 T3 DK 0811063T3
Authority
DK
Denmark
Prior art keywords
chemokine receptors
antibodies
modulators
ligands
chemokine receptor
Prior art date
Application number
DK96945669T
Other languages
Danish (da)
English (en)
Inventor
Patrick W Gray
Vicki L Schweickart
Carol J Raport
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24302427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0811063(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of DK0811063T3 publication Critical patent/DK0811063T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96945669T 1995-12-20 1996-12-20 Kemokin-receptor 88C og dens antistoffer DK0811063T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/575,967 US6265184B1 (en) 1995-12-20 1995-12-20 Polynucleotides encoding chemokine receptor 88C
US08/661,393 US6268477B1 (en) 1995-12-20 1996-06-07 Chemokine receptor 88-C

Publications (1)

Publication Number Publication Date
DK0811063T3 true DK0811063T3 (da) 2006-04-10

Family

ID=24302427

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96945669T DK0811063T3 (da) 1995-12-20 1996-12-20 Kemokin-receptor 88C og dens antistoffer
DK07013395.4T DK1870465T3 (da) 1995-12-20 1996-12-20 Fremgangsmåde til chemokinreceptor 88C

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07013395.4T DK1870465T3 (da) 1995-12-20 1996-12-20 Fremgangsmåde til chemokinreceptor 88C

Country Status (17)

Country Link
US (7) US6265184B1 (fr)
EP (3) EP0811063B9 (fr)
JP (4) JP3288384B2 (fr)
CN (2) CN1222617C (fr)
AT (2) ATE309349T1 (fr)
AU (1) AU730463B2 (fr)
BR (1) BR9607300A (fr)
CA (1) CA2213331C (fr)
CZ (1) CZ261097A3 (fr)
DE (2) DE69638128D1 (fr)
DK (2) DK0811063T3 (fr)
ES (2) ES2255716T5 (fr)
HU (1) HUP9801127A3 (fr)
NO (2) NO973800L (fr)
PL (2) PL192294B1 (fr)
SK (1) SK112897A3 (fr)
WO (1) WO1997022698A2 (fr)

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US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
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US7018627B1 (en) 1995-06-07 2006-03-28 Icos Corporation Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
US7118859B2 (en) * 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
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ATE428785T1 (de) 1996-03-01 2009-05-15 Euroscreen Sa Aktive und inactive cc-chemokinrezeptoren und nukleinsäuremoleküle, die für diesen rezeptor kodieren
US7858298B1 (en) * 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
US6344545B1 (en) * 1996-06-14 2002-02-05 Progenics Pharmaceuticals, Inc. Method for preventing HIV-1 infection of CD4+ cells
EP0915969A4 (fr) 1996-04-02 2002-04-17 Progenics Pharm Inc Methode de prevention de l'infection des cellules cd4+ par le vih-1
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EP1012190A4 (fr) * 1996-04-26 2004-04-28 Merck & Co Inc Recepteur d'eotaxine eosinophile
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US5939320A (en) * 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US6258527B1 (en) 1996-05-20 2001-07-10 The Aaron Diamond Aids Research Center Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
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US20040086528A1 (en) * 1996-06-14 2004-05-06 Progenics Pharmaceuticals, Inc. Uses of a chemokine receptor for inhibiting HIV-1 infection
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US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
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US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
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US6287805B1 (en) 1998-03-20 2001-09-11 Millennium Pharmaceuticals, Inc. Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor
CA2235420A1 (fr) 1998-06-17 1999-12-17 Paolo Renzi Oligonucleoside antisens pour traiter ou prevenir les maladies atopiques et la proliferation de cellules neoplastiques
US20040228869A1 (en) * 1998-12-16 2004-11-18 Progenics Pharmaceuticals, Inc. Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto
US20080015348A1 (en) * 1998-12-16 2008-01-17 Progenics Pharmaceuticals, Inc. Nucleic acids encoding polypeptides of anti-CCR5 antibodies
JP4712975B2 (ja) 1999-01-12 2011-06-29 ケンブリッジ エンタープライズ リミティド 炎症反応を阻害又は増強するための組成物及び方法
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
JP2003523744A (ja) * 2000-02-09 2003-08-12 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Ｃｃｒ５に対する抗体
WO2002014532A2 (fr) 2000-08-15 2002-02-21 Millennium Pharmaceuticals, Inc. Methode d'identification de modulateurs des fonctions induites par 'mec' de ccr3 et/ou ccr10
US7138119B2 (en) * 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7175988B2 (en) * 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7060273B2 (en) * 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US20030104496A1 (en) * 2001-11-30 2003-06-05 Cytokinetics, Inc. Novel motor protein of P. falciparum and methods for its use
US7393934B2 (en) * 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
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US7122185B2 (en) * 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
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MX2007005083A (es) 2004-10-29 2007-10-03 Topigen Pharmaceuticals Inc Oligonucleotidos antisentido para tratar alergias y proliferacion celular neoplastica.
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US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
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EP2873423B1 (fr) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Trimères de glycoprotéines d'enveloppe du vih -1 soluble
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (fr) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Trimères de glycoprotéines de l'enveloppe du vih-1 soluble
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US4886742A (en) 1987-06-15 1989-12-12 Coulter Corporation Enzyme immunoassay for detecting HIV antigens in human sera
US4888920A (en) 1988-08-24 1989-12-26 Marulic Walter J Gutter anti-clogging device
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ATE428785T1 (de) 1996-03-01 2009-05-15 Euroscreen Sa Aktive und inactive cc-chemokinrezeptoren und nukleinsäuremoleküle, die für diesen rezeptor kodieren
US5939320A (en) 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
AU3375697A (en) 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
EP0956044A4 (fr) 1996-06-14 2005-01-05 Progenics Pharm Inc Utilisations d'un recepteur de la chemokine dans l'inhibition de l'infection par le vih-1
US5994515A (en) * 1996-06-25 1999-11-30 Trustees Of The University Of Pennsylvania Antibodies directed against cellular coreceptors for human immunodeficiency virus and methods of using the same

Also Published As

Publication number Publication date
CZ261097A3 (cs) 1998-06-17
HUP9801127A2 (hu) 1998-08-28
JP2001029089A (ja) 2001-02-06
US20040230037A1 (en) 2004-11-18
JP2009065976A (ja) 2009-04-02
DE69638128D1 (de) 2010-04-01
US20080032336A1 (en) 2008-02-07
EP0811063A2 (fr) 1997-12-10
JPH11503028A (ja) 1999-03-23
EP1870465B1 (fr) 2010-02-17
US6797811B1 (en) 2004-09-28
EP1642975A3 (fr) 2006-04-12
DE69635406D1 (de) 2005-12-15
US6268477B1 (en) 2001-07-31
EP1870465A3 (fr) 2008-04-23
DE69635406T2 (de) 2006-08-03
EP0811063B9 (fr) 2014-04-23
JP2001264324A (ja) 2001-09-26
NO20052202L (no) 1997-10-20
ATE309349T1 (de) 2005-11-15
MX9706316A (es) 1997-11-29
NO20052202D0 (no) 2005-05-04
DE69635406T3 (de) 2014-04-24
US20020150888A1 (en) 2002-10-17
EP1870465A2 (fr) 2007-12-26
EP0811063B2 (fr) 2013-12-04
EP1642975A2 (fr) 2006-04-05
US6265184B1 (en) 2001-07-24
PL192071B1 (pl) 2006-08-31
SK112897A3 (en) 1998-07-08
US20050260565A1 (en) 2005-11-24
HUP9801127A3 (en) 2000-12-28
CA2213331C (fr) 2011-09-27
CN1183805A (zh) 1998-06-03
EP0811063B1 (fr) 2005-11-09
ES2255716T5 (es) 2014-03-21
DK1870465T3 (da) 2010-05-17
CA2213331A1 (fr) 1997-06-26
BR9607300A (pt) 1997-11-25
ES2341371T3 (es) 2010-06-18
CN1222617C (zh) 2005-10-12
NO327506B1 (no) 2009-07-27
AU1689297A (en) 1997-07-14
PL321937A1 (en) 1998-01-05
US7662548B2 (en) 2010-02-16
NO973800L (no) 1997-10-20
ES2255716T3 (es) 2006-07-01
NO973800D0 (no) 1997-08-19
WO1997022698A2 (fr) 1997-06-26
CN1827646A (zh) 2006-09-06
JP3288384B2 (ja) 2002-06-04
PL192294B1 (pl) 2006-09-29
AU730463B2 (en) 2001-03-08
WO1997022698A3 (fr) 1997-09-12
ATE458052T1 (de) 2010-03-15

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