DK0815074T3 - O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse - Google Patents

O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse

Info

Publication number
DK0815074T3
DK0815074T3 DK96901562T DK96901562T DK0815074T3 DK 0815074 T3 DK0815074 T3 DK 0815074T3 DK 96901562 T DK96901562 T DK 96901562T DK 96901562 T DK96901562 T DK 96901562T DK 0815074 T3 DK0815074 T3 DK 0815074T3
Authority
DK
Denmark
Prior art keywords
phenylalanium
carbamoyl
compounds
preparation
phenylalanium compounds
Prior art date
Application number
DK96901562T
Other languages
English (en)
Inventor
Yong Moon Choi
Dong Il Han
Yong Kil Kim
Original Assignee
Sk Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Corp filed Critical Sk Corp
Application granted granted Critical
Publication of DK0815074T3 publication Critical patent/DK0815074T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96901562T 1995-02-11 1996-02-08 O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse DK0815074T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019950002543A KR0173862B1 (ko) 1995-02-11 1995-02-11 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
PCT/KR1996/000018 WO1996024577A1 (en) 1995-02-11 1996-02-08 O-carbamoyl-(d)-phenylalanilol compounds and process for preparing the same

Publications (1)

Publication Number Publication Date
DK0815074T3 true DK0815074T3 (da) 2002-01-28

Family

ID=19408007

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96901562T DK0815074T3 (da) 1995-02-11 1996-02-08 O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse

Country Status (11)

Country Link
US (1) US5705640C1 (da)
EP (1) EP0815074B1 (da)
JP (1) JP3828574B2 (da)
KR (1) KR0173862B1 (da)
CN (1) CN1070846C (da)
CA (1) CA2212326C (da)
DE (1) DE69615668T2 (da)
DK (1) DK0815074T3 (da)
ES (1) ES2165485T3 (da)
PT (1) PT815074E (da)
WO (1) WO1996024577A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0173863B1 (ko) * 1995-04-10 1999-04-01 조규향 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
WO1998015526A1 (en) * 1996-10-10 1998-04-16 Sk Corporation O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same
CA2587481A1 (en) * 2004-10-28 2006-05-11 Sk Corporation Phenylalkylamino carbamates adjunctive therapy for depression
PL1890684T3 (pl) * 2005-06-08 2014-05-30 Sk Biopharmaceuticals Co Ltd Leczenie zaburzeń snu i czuwania
ES2344469T3 (es) 2005-06-22 2010-08-27 Sk Holdings Co., Ltd. Tratamiento de disfuncion sexual.
EA200970377A1 (ru) * 2006-10-13 2009-10-30 Янссен Фармацевтика Нв Композиции фенилалкиламинокарбамата
US8642772B2 (en) 2008-10-14 2014-02-04 Sk Biopharmaceuticals Co., Ltd. Piperidine compounds, pharmaceutical composition comprising the same and its use
MX2012000034A (es) 2009-06-22 2012-02-21 Sk Biopharmaceuticals Co Ltd Metodos para el tratamiento o la prevencion de la fatiga.
US8232315B2 (en) * 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
US8927602B2 (en) 2009-11-06 2015-01-06 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
EP2496228B1 (en) * 2009-11-06 2014-01-15 SK Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
PT2968208T (pt) 2013-03-13 2022-10-28 Aerial Biopharma Llc Tratamento da cataplexia
US9226910B2 (en) 2013-07-18 2016-01-05 Jazz Pharmaceuticals International Iii Limited Treatment for obesity
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
TWI655179B (zh) 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
SG11201901998WA (en) 2016-09-06 2019-04-29 Jazz Pharmaceuticals International Iii Ltd Solvate form of (r)-2-amino-3-phenylpropyl carbamate
CN110049966A (zh) 2016-10-06 2019-07-23 杰资制药国际三期有限公司 氨基甲酰基苯丙氨醇化合物及其用途
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
WO2019027941A1 (en) 2017-07-31 2019-02-07 Jazz Pharmaceuticals International Iii Limited CARBAMOYL PHENYLALANINOL ANALOGUES AND USES THEREOF
CN110655500B (zh) * 2018-06-28 2020-12-08 浙江京新药业股份有限公司 氨基甲酸酯衍生物及其制备方法和用途
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물
AU2022390879A1 (en) * 2021-11-16 2024-06-13 Axsome Malta Ltd. Methods and compositions for treating cognitive impairment
KR20260016554A (ko) 2023-05-30 2026-02-03 액섬 테라퓨틱스, 인크. 폐쇄성 수면 무호흡 및 과도한 주간 졸림증과 연관된 인지 장애를 갖고 있는 대상체에서의 인지 장애를 치료하기 위한 솔리암페톨
KR20260033050A (ko) 2023-06-29 2026-03-10 액섬 테라퓨틱스, 인크. 수유 여성에게 솔리암페톨을 투여하는 방법
WO2025042959A1 (en) 2023-08-21 2025-02-27 Axsome Therapeutics, Inc. Use of solriamfetol for the treatment of orphan diseases
WO2025165760A1 (en) 2024-01-29 2025-08-07 Axsome Therapeutics, Inc. Phenylalkylamino carbamates for use in the treatment of attention deficit/hyperactivity disorder

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470277A1 (de) * 1963-04-18 1969-05-29 Siegfried Ag Verfahren zur Herstellung von spasmolytische und tremolytische Eigenschaften aufweisenden Carbaminaten
FR8411M (da) * 1968-12-31 1971-03-31
AT387572B (de) * 1983-05-20 1989-02-10 Ferrosan Ab Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden
KR100197892B1 (ko) * 1994-09-09 1999-06-15 남창우 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법

Also Published As

Publication number Publication date
CN1173863A (zh) 1998-02-18
CN1070846C (zh) 2001-09-12
KR960031427A (ko) 1996-09-17
DE69615668T2 (de) 2002-07-11
EP0815074A1 (en) 1998-01-07
WO1996024577A1 (en) 1996-08-15
EP0815074B1 (en) 2001-10-04
JPH11501617A (ja) 1999-02-09
JP3828574B2 (ja) 2006-10-04
CA2212326C (en) 2008-12-23
PT815074E (pt) 2002-03-28
ES2165485T3 (es) 2002-03-16
US5705640C1 (en) 2001-03-20
US5705640A (en) 1998-01-06
CA2212326A1 (en) 1996-08-15
KR0173862B1 (ko) 1999-04-01
DE69615668D1 (de) 2001-11-08

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