DK0817862T3 - Enzymatisk enkelt beholder-sulfateringsproces, hvor der anvendes 3'phosphoadenosin-5'phosphosulfat og genbrugte phosphorylerede adenosin-mellemprodukter - Google Patents

Enzymatisk enkelt beholder-sulfateringsproces, hvor der anvendes 3'phosphoadenosin-5'phosphosulfat og genbrugte phosphorylerede adenosin-mellemprodukter

Info

Publication number: DK0817862T3
Authority: DK; Denmark
Prior art keywords: recycled; phosphoadenosine; phosphosulfate; single vessel; phosphorylated adenosine
Prior art date: 1995-03-22

Application number

DK96908871T

Other languages

English (en)

Inventor

Chi-Huey Wong

Chun-Hung Lin

Gwo-Jenn Shen

Original Assignee

Scripps Research Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-22

Filing date

1996-03-21

Publication date

2003-06-02

1996-03-21 Application filed by Scripps Research Inst filed Critical Scripps Research Inst

2003-06-02 Application granted granted Critical

2003-06-02 Publication of DK0817862T3 publication Critical patent/DK0817862T3/da

Links

150000003838 adenosines Chemical class 0.000 title abstract 2
230000002255 enzymatic effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
GACDQMDRPRGCTN-KQYNXXCUSA-N 3'-phospho-5'-adenylyl sulfate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](OP(O)(O)=O)[C@H]1O GACDQMDRPRGCTN-KQYNXXCUSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
230000019635 sulfation Effects 0.000 title 1
238000005670 sulfation reaction Methods 0.000 title 1
102000004190 Enzymes Human genes 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
108010022348 Sulfate adenylyltransferase Proteins 0.000 abstract 2
102100040149 Adenylyl-sulfate kinase Human genes 0.000 abstract 1
102000004523 Sulfate Adenylyltransferase Human genes 0.000 abstract 1
102000004896 Sulfotransferases Human genes 0.000 abstract 1
108090001033 Sulfotransferases Proteins 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P11/00—Preparation of sulfur-containing organic compounds
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DK96908871T 1995-03-22 1996-03-21 Enzymatisk enkelt beholder-sulfateringsproces, hvor der anvendes 3'phosphoadenosin-5'phosphosulfat og genbrugte phosphorylerede adenosin-mellemprodukter DK0817862T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/408,774 US5919673A (en)	1995-03-22	1995-03-22	One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates
PCT/US1996/003792 WO1996029424A1 (en)	1995-03-22	1996-03-21	One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates

Publications (1)

Publication Number	Publication Date
DK0817862T3 true DK0817862T3 (da)	2003-06-02

Family

ID=23617712

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96908871T DK0817862T3 (da)	1995-03-22	1996-03-21	Enzymatisk enkelt beholder-sulfateringsproces, hvor der anvendes 3'phosphoadenosin-5'phosphosulfat og genbrugte phosphorylerede adenosin-mellemprodukter

Country Status (7)

Country	Link
US (1)	US5919673A (da)
EP (1)	EP0817862B1 (da)
AT (1)	ATE232908T1 (da)
AU (1)	AU5257096A (da)
DE (1)	DE69626277T2 (da)
DK (1)	DK0817862T3 (da)
WO (1)	WO1996029424A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9620209D0 (en) *	1996-09-27	1996-11-13	Cemu Bioteknik Ab	Method of sequencing DNA
GB9626815D0 (en)	1996-12-23	1997-02-12	Cemu Bioteknik Ab	Method of sequencing DNA
US6274320B1 (en) *	1999-09-16	2001-08-14	Curagen Corporation	Method of sequencing a nucleic acid
US7211390B2 (en) *	1999-09-16	2007-05-01	454 Life Sciences Corporation	Method of sequencing a nucleic acid
US7244559B2 (en) *	1999-09-16	2007-07-17	454 Life Sciences Corporation	Method of sequencing a nucleic acid
DE602004026033D1 (de) *	2003-01-29	2010-04-29	454 Corp	Zweiendige sequenzierung
US7575865B2 (en) *	2003-01-29	2009-08-18	454 Life Sciences Corporation	Methods of amplifying and sequencing nucleic acids
CA3126805A1 (en)	2019-01-15	2020-07-23	Optimvia, Llc	Engineered aryl sulfate-dependent enzymes
AU2020310172A1 (en)	2019-07-09	2022-03-03	Optimvia Llc	Methods for synthesizing anticoagulant polysaccharides
CN112708569B (zh) *	2019-10-24	2022-11-01	华熙生物科技股份有限公司	发酵生产硫酸软骨素的酵母工程菌及其应用
WO2021199445A1 (en) *	2020-04-03	2021-10-07	Rensselaer Polytechnic Institute	Method for producing sulfated polysaccharide and method for producing paps
CN113046402B (zh) *	2020-09-30	2023-04-28	江南大学	一种基于构建双功能酶合成paps的方法
WO2024222534A1 (zh) *	2023-04-28	2024-10-31	江南大学	一种基于aps和paps为活性磺酸供体的再生系统构建与应用方法
CN118853719A (zh) *	2024-06-26	2024-10-29	和度生物技术(上海)有限公司	一种用于催化胆固醇硫酸酯合成的工程微生物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4266048A (en) *	1977-10-11	1981-05-05	The United States Of America As Represented By The Department Of Health, Education And Welfare	Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS)
JP3098591B2 (ja) *	1991-11-14	2000-10-16	ユニチカ株式会社	３’−ホスホアデノシン−５’−ホスホ硫酸の製造方法

1995
- 1995-03-22 US US08/408,774 patent/US5919673A/en not_active Expired - Lifetime
1996
- 1996-03-21 DK DK96908871T patent/DK0817862T3/da active
- 1996-03-21 AU AU52570/96A patent/AU5257096A/en not_active Abandoned
- 1996-03-21 DE DE69626277T patent/DE69626277T2/de not_active Expired - Fee Related
- 1996-03-21 EP EP96908871A patent/EP0817862B1/en not_active Expired - Lifetime
- 1996-03-21 WO PCT/US1996/003792 patent/WO1996029424A1/en not_active Ceased
- 1996-03-21 AT AT96908871T patent/ATE232908T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU5257096A (en)	1996-10-08
DE69626277T2 (de)	2004-01-29
ATE232908T1 (de)	2003-03-15
WO1996029424A1 (en)	1996-09-26
US5919673A (en)	1999-07-06
EP0817862B1 (en)	2003-02-19
DE69626277D1 (de)	2003-03-27
EP0817862A4 (en)	1998-10-21
EP0817862A1 (en)	1998-01-14

Publication	Publication Date	Title
AU5257096A (en)	1996-10-08	One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates
ES2180757T3 (es)	2003-02-16	Sintesis enzimatica mejorada de oligosacaridos.
IL109381A0 (en)	1994-07-31	Processes for the isolation, selection and propagation of animal stem cells, genetically modified animals and animal cells, and vectors for the production thereof
MX9800499A (es)	1998-04-30	Inhibicion de la expresion de genes.
EP0674516A4 (da)	1995-10-25
ATE150487T1 (de)	1997-04-15	Verfahren zur herstellung von cytidin-diphosphat- cholin
NO975557D0 (no)	1997-12-02	Immortalisering og dismortalisering av celler
WO2001014566A3 (en)	2001-09-20	Enzymatic synthesis of deoxyribonucleosides
Kazarinoff et al.	1973	N-(5′-phospho-4′-pyridoxyl) amines as substrates for pyridoxine (pyridoxamine) 5′-phosphate oxidase
EP1672061A3 (en)	2006-07-12	Nucleotide sequences encoding ACC synthase enzymes
Ishii et al.	1989	Enzymatic production of 5-methyluridine from purine nucleosides and thymine by Erwinia carotovora AJ-2992
Zhang et al.	1995	Novel enzymatic cyclizations of pyridine nucleotide analogs: Cyclic-GDP-ribose and cyclic-HDP-ribose
AU4648985A (en)	1986-04-24	Depolymerase enzymes and treatment of fireblight
DE69920749D1 (de)	2004-11-04	Rekombinante bakterienstämme zur herstellung von natürlichen nucleosiden, sowie von modifizierten analogen davon
ES2181897T3 (es)	2003-03-01	Composicion enzimatica.
Shimizu et al.	1983	A high yield method for the preparative synthesis of coenzyme A by combination of chemical and enzymic reactions
DE69322974D1 (de)	1999-02-18	Enzymatisches triglycerid-umsetzverfahren
DK0751218T3 (da)	2005-01-10	Saccharose-stofskifte-mutanter
EP0189322A3 (en)	1986-10-08	Enzymatic synthesis of s-adenosylmethionine
MX9700951A (es)	1997-05-31	Promotor de fblato.
JPS5329994A (en)	1978-03-20	Continuous reaction using enzymes or microorganisms
MX9803566A (es)	1998-09-30	Un metodo para expresar beta-caseina humana, recombinante, fosforilada en un sistema bacteriano.
AU2002226085A1 (en)	2002-06-24	Active-site engineering of nucleotidyltransferases and enzymatic methods for the synthesis of natural and "unnatural" udp- and nucleotide sugars
ATE42341T1 (de)	1989-05-15	Herstellung von uridin.
DE59609945D1 (de)	2003-01-16	Verfahren zur enzymatischen Synthese von Nukleotid-6-desoxy-D-xylo-4-hexulosen