DK0824100T3 - Tricykliske piperidinylaminoforbindelser som substans P-antagonister - Google Patents

Tricykliske piperidinylaminoforbindelser som substans P-antagonister

Info

Publication number: DK0824100T3
Authority: DK; Denmark
Prior art keywords: compounds; chem; alkoxy; piperidinylamino; tricyclic
Prior art date: 1996-08-14

Application number

DK97306054T

Other languages

Danish (da)

English (en)

Inventor

Hiroki Koike

Hiroaki Wakabayashi

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-14

Filing date

1997-08-08

Publication date

2000-11-20

1997-08-08 Application filed by Pfizer filed Critical Pfizer

2000-11-20 Application granted granted Critical

2000-11-20 Publication of DK0824100T3 publication Critical patent/DK0824100T3/da

Links

-1 piperidinylamino compounds Chemical class 0.000 title 1
239000003890 substance P antagonist Substances 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
210000003169 central nervous system Anatomy 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
241000590002 Helicobacter pylori Species 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
206010042496 Sunburn Diseases 0.000 abstract 1
206010046543 Urinary incontinence Diseases 0.000 abstract 1
206010047700 Vomiting Diseases 0.000 abstract 1
230000002411 adverse Effects 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000033115 angiogenesis Effects 0.000 abstract 1
208000010643 digestive system disease Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000018685 gastrointestinal system disease Diseases 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229940037467 helicobacter pylori Drugs 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK97306054T 1996-08-14 1997-08-08 Tricykliske piperidinylaminoforbindelser som substans P-antagonister DK0824100T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IB9600798		1996-08-14

Publications (1)

Publication Number	Publication Date
DK0824100T3 true DK0824100T3 (da)	2000-11-20

Family

ID=11004463

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97306054T DK0824100T3 (da)	1996-08-14	1997-08-08	Tricykliske piperidinylaminoforbindelser som substans P-antagonister

Country Status (10)

Country	Link
US (2)	US5972930A (de)
EP (1)	EP0824100B1 (de)
AT (1)	ATE196470T1 (de)
BR (1)	BR9704352A (de)
CA (1)	CA2212784C (de)
DE (1)	DE69703143T2 (de)
DK (1)	DK0824100T3 (de)
ES (1)	ES2150739T3 (de)
GR (1)	GR3034775T3 (de)
MX (1)	MX9706196A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2409582C2 (ru) *	2004-08-31	2011-01-20	Глэксо Груп Лимитед	Конденсированные трициклические производные для лечения психотических расстройств
PE20060653A1 (es) *	2004-08-31	2006-09-27	Glaxo Group Ltd	Derivados triciclicos condensados como moduladores del receptor 5-ht1
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5232929A (en) *	1990-11-28	1993-08-03	Pfizer Inc.	3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
FI990419A7 (fi) *	1991-06-20	1999-02-26	Pfizer	Typpeä sisältävien hetrosyklisten yhdisteiden fluorialkoksibentsyyliaminojohdannaiset
ATE208376T1 (de) *	1992-08-19	2001-11-15	Pfizer	Substituierte benzylamin-stickstoff enthaltende nichtaromatische heterocyclen
IS4208A (is) *	1993-09-22	1995-03-23	Glaxo Group Limited	3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
MX9800187A (es) *	1995-07-07	1998-05-31	Pfizer	Compuestos de benzolactama substituidos como antagonistas de la substancia p.
TW340842B (en) *	1995-08-24	1998-09-21	Pfizer	Substituted benzylaminopiperidine compounds

1996
- 1996-08-14 MX MX9706196A patent/MX9706196A/es not_active IP Right Cessation
1997
- 1997-08-07 US US08/907,374 patent/US5972930A/en not_active Expired - Fee Related
- 1997-08-08 DK DK97306054T patent/DK0824100T3/da active
- 1997-08-08 AT AT97306054T patent/ATE196470T1/de not_active IP Right Cessation
- 1997-08-08 EP EP97306054A patent/EP0824100B1/de not_active Expired - Lifetime
- 1997-08-08 ES ES97306054T patent/ES2150739T3/es not_active Expired - Lifetime
- 1997-08-08 DE DE69703143T patent/DE69703143T2/de not_active Expired - Fee Related
- 1997-08-12 CA CA002212784A patent/CA2212784C/en not_active Expired - Fee Related
- 1997-08-13 BR BR9704352A patent/BR9704352A/pt not_active Application Discontinuation
1999
- 1999-07-12 US US09/351,011 patent/US6143767A/en not_active Expired - Fee Related
2000
- 2000-11-08 GR GR20000402464T patent/GR3034775T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2212784A1 (en)	1998-02-14
DE69703143T2 (de)	2001-03-22
EP0824100B1 (de)	2000-09-20
GR3034775T3 (en)	2001-02-28
ES2150739T3 (es)	2000-12-01
CA2212784C (en)	2001-02-27
EP0824100A1 (de)	1998-02-18
ATE196470T1 (de)	2000-10-15
DE69703143D1 (de)	2000-10-26
US5972930A (en)	1999-10-26
US6143767A (en)	2000-11-07
MX9706196A (es)	1998-02-28
BR9704352A (pt)	1999-01-05

Publication	Publication Date	Title
KR100366902B1 (ko)	2003-01-09	섭스턴스 ｐ 길항제로서 피페리디닐아미노메틸트리플루오로메틸 시클릭 에테르 화합물
MY114800A (en)	2003-01-31	Substituted benzylaminopiperidine compounds
DE69206820D1 (de)	1996-01-25	1,3-Dihydro-2H-Imidano 4,5-b-quinolin-2-ein Derivate als Phosphodiestenase Hemmer
LU91943I2 (fr)	2012-04-16	Tafluprost et ses dérivés pharmaceutiquement acceptables (SAFLUTAN®)
DE60138732D1 (de)	2009-06-25	Muscarin-rezeptor-agonisten
LU92113I2 (fr)	2013-02-12	Perampanel et ses dérivés pharmaceutiquement acceptables (FYCOMPA)
SE0104332D0 (sv)	2001-12-19	Therapeutic agents
ES2180693T3 (es)	2003-02-16	3-((bencil 5-sustituido)amino)-2-fenilpiperidinas como antagonistas de la sustancia p.
DK0824100T3 (da)	2000-11-20	Tricykliske piperidinylaminoforbindelser som substans P-antagonister
SE8505369D0 (sv)	1985-11-13	New thienopyridine derivatives, a process of preparation thereof and therapeutic compositions containing the same
DE69703725D1 (de)	2001-01-25	Tetrazolyl-substituierte Chinuclidine als Substanz P Antagonisten
ES2193047T3 (es)	2003-11-01	(3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas.
ES2141134T3 (es)	2000-03-16	Derivados de carbamoil pirrolidona para el tratamiento de la depresion y de los trastornos cerebrovasculares.
DK1049670T3 (da)	2002-11-11	Azetidincarboxamidderivater til behandling af CNS-lidelser
OA08045A (fr)	1987-01-31	Nouveaux dérivés de l'isoxazoloquinoléinone, procédé et intermédiaires de préparation, application à titre de médicaments, et compositions les renferment.