DK0826375T3 - Anvendelse af komplekse lipider som stabiliserende tilsætningsstoffer til farmaceutiske præparater af fordöjelsesenzymblandinger - Google Patents

Anvendelse af komplekse lipider som stabiliserende tilsætningsstoffer til farmaceutiske præparater af fordöjelsesenzymblandinger

Info

Publication number
DK0826375T3
DK0826375T3 DK97114330T DK97114330T DK0826375T3 DK 0826375 T3 DK0826375 T3 DK 0826375T3 DK 97114330 T DK97114330 T DK 97114330T DK 97114330 T DK97114330 T DK 97114330T DK 0826375 T3 DK0826375 T3 DK 0826375T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical preparations
digestive enzyme
stabilizing additives
enzyme mixtures
complex lipids
Prior art date
Application number
DK97114330T
Other languages
English (en)
Inventor
Manfred Galle
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Application granted granted Critical
Publication of DK0826375T3 publication Critical patent/DK0826375T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
DK97114330T 1996-08-28 1997-08-20 Anvendelse af komplekse lipider som stabiliserende tilsætningsstoffer til farmaceutiske præparater af fordöjelsesenzymblandinger DK0826375T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19634752 1996-08-28
DE19724845A DE19724845A1 (de) 1996-08-28 1997-06-12 Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (1)

Publication Number Publication Date
DK0826375T3 true DK0826375T3 (da) 2005-01-24

Family

ID=26028823

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97114330T DK0826375T3 (da) 1996-08-28 1997-08-20 Anvendelse af komplekse lipider som stabiliserende tilsætningsstoffer til farmaceutiske præparater af fordöjelsesenzymblandinger

Country Status (21)

Country Link
US (1) US5993806A (da)
EP (1) EP0826375B1 (da)
JP (1) JP4593697B2 (da)
CN (1) CN1199694C (da)
AR (1) AR008807A1 (da)
AT (1) ATE284225T1 (da)
AU (1) AU722151B2 (da)
BR (1) BR9704554B1 (da)
CA (1) CA2213151C (da)
CZ (1) CZ295329B6 (da)
DE (2) DE19724845A1 (da)
DK (1) DK0826375T3 (da)
EE (1) EE04179B1 (da)
ES (1) ES2235206T3 (da)
HU (1) HUP9701437A3 (da)
NO (1) NO973940L (da)
NZ (1) NZ328616A (da)
PL (1) PL190140B1 (da)
PT (1) PT826375E (da)
SK (1) SK284639B6 (da)
TR (1) TR199700872A3 (da)

Families Citing this family (25)

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US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) * 2000-08-03 2000-09-27 Danisco Solid phase glycerolysis
JP4139215B2 (ja) * 2000-11-02 2008-08-27 シリアン アクチェンゲゼルシャフト 消化を促進するための薬剤としての繊毛虫から得られた酵素の使用
US20030099626A1 (en) * 2001-11-20 2003-05-29 Health Education Corporation Nutrient absorption enhancing compositions and methods
ES2314646T3 (es) * 2004-03-22 2009-03-16 Solvay Pharmaceuticals Gmbh Composiciones farmaceuticas por via de productos que contienen lipasa , en particular de pancreatina, que contienen tensioactivos.
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
US7947321B2 (en) * 2005-07-20 2011-05-24 Brophy James S Modification of particle morphology to improve product functionality
HUE031042T2 (en) 2005-07-29 2017-06-28 Abbott Laboratories Gmbh Methods for producing pancreatin powder with low viral content
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) * 2006-07-20 2011-07-28 Brophy James S Modification of particle morphology to improve product functionality
US8444967B2 (en) 2010-07-09 2013-05-21 Master Supplements, Inc. Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
WO2010085975A1 (de) * 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches präparat enthaltend lipase bakteriellen ursprungs
UA111726C2 (uk) 2010-10-01 2016-06-10 Апталіс Фарма Лімітед Препарат панкреліпази низької сили з кишковорозчинним покриттям
CN106163544A (zh) 2013-08-09 2016-11-23 阿勒根制药国际有限公司 适于经肠施用的消化酶组合物
CN106659773A (zh) * 2013-11-05 2017-05-10 阿勒根制药国际有限公司 高效的胰酶药物组合物
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
MX391630B (es) * 2014-11-05 2025-03-19 Abbott Laboratories Gmbh Procesos para la producción de composiciones con perfil de seguridad mejorado teniendo actividad lipasa y composiciones adecuadas para medicamentos
WO2016126970A1 (en) 2015-02-04 2016-08-11 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114862A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956483A (en) * 1968-10-24 1976-05-11 Wilson Pharmaceutical & Chemical Corporation Preparing pancreatin
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) * 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
JPS58148814A (ja) * 1982-03-01 1983-09-05 Fujimoto Seiyaku Kk 消化酵素軟カプセル剤
JPS59169491A (ja) * 1983-03-15 1984-09-25 Duskin Franchise Co Ltd 酵素の安定化法
JPH0229950A (ja) * 1988-07-18 1990-01-31 Nec Corp 光ディスク
JP2679852B2 (ja) * 1989-11-29 1997-11-19 株式会社サム研究所 経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
ES2157898T3 (es) * 1991-01-24 2001-09-01 Martek Corp Aceites microbianos y usos de los mismos.
DE4200002A1 (de) * 1992-01-02 1993-07-08 Rudolf V Dipl Chem Dr Noronha Reinigungstablette fuer die zahnprothesen
AU7656894A (en) * 1993-09-15 1995-04-03 Unilever Plc Skin care method and composition
JPH09125096A (ja) * 1995-10-30 1997-05-13 Koei Sangyo:Kk 液状天然油脂洗剤

Also Published As

Publication number Publication date
DE59712108D1 (de) 2005-01-13
AR008807A1 (es) 2000-02-23
NO973940L (no) 1998-03-02
SK115997A3 (en) 1998-07-08
NO973940D0 (no) 1997-08-27
PL190140B1 (pl) 2005-11-30
HU9701437D0 (en) 1997-10-28
BR9704554B1 (pt) 2011-12-27
CZ295329B6 (cs) 2005-07-13
DE19724845A1 (de) 1998-03-05
HK1005224A1 (en) 1998-12-31
AU3530997A (en) 1998-03-05
HUP9701437A2 (hu) 1998-03-30
CA2213151C (en) 2008-04-01
PT826375E (pt) 2005-02-28
US5993806A (en) 1999-11-30
CZ218497A3 (cs) 1998-03-18
EP0826375A3 (de) 2002-08-14
ATE284225T1 (de) 2004-12-15
EE04179B1 (et) 2003-12-15
EP0826375A2 (de) 1998-03-04
EP0826375B1 (de) 2004-12-08
EE9700249A (et) 1998-04-15
CA2213151A1 (en) 1998-02-28
BR9704554A (pt) 1998-09-15
CN1174743A (zh) 1998-03-04
TR199700872A2 (xx) 1999-04-21
ES2235206T3 (es) 2005-07-01
SK284639B6 (sk) 2005-08-04
CN1199694C (zh) 2005-05-04
PL321825A1 (en) 1998-03-02
JP4593697B2 (ja) 2010-12-08
AU722151B2 (en) 2000-07-20
NZ328616A (en) 1999-01-28
TR199700872A3 (tr) 1999-04-21
HUP9701437A3 (en) 2001-03-28
JPH1077236A (ja) 1998-03-24

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