DK0839152T3 - Kombinatoriske biblioteker af mærkede, biokemiske forbindelser og fremgangsmåde til fremstilling af disse - Google Patents

Kombinatoriske biblioteker af mærkede, biokemiske forbindelser og fremgangsmåde til fremstilling af disse

Info

Publication number
DK0839152T3
DK0839152T3 DK96919473T DK96919473T DK0839152T3 DK 0839152 T3 DK0839152 T3 DK 0839152T3 DK 96919473 T DK96919473 T DK 96919473T DK 96919473 T DK96919473 T DK 96919473T DK 0839152 T3 DK0839152 T3 DK 0839152T3
Authority
DK
Denmark
Prior art keywords
labeled
labeled biochemical
biochemical compounds
combinatorial libraries
processes
Prior art date
Application number
DK96919473T
Other languages
English (en)
Inventor
Hao Chen
Jonathan M Brown
F C Thomas Allnutt
Richard Radmer
Original Assignee
Martek Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Biosciences Corp filed Critical Martek Biosciences Corp
Application granted granted Critical
Publication of DK0839152T3 publication Critical patent/DK0839152T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK96919473T 1995-06-21 1996-06-13 Kombinatoriske biblioteker af mærkede, biokemiske forbindelser og fremgangsmåde til fremstilling af disse DK0839152T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49330095A 1995-06-21 1995-06-21
PCT/US1996/010526 WO1997000887A1 (en) 1995-06-21 1996-06-13 Combinatorial libraries of labeled biochemical compounds and methods for producing same

Publications (1)

Publication Number Publication Date
DK0839152T3 true DK0839152T3 (da) 2002-07-08

Family

ID=23959668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96919473T DK0839152T3 (da) 1995-06-21 1996-06-13 Kombinatoriske biblioteker af mærkede, biokemiske forbindelser og fremgangsmåde til fremstilling af disse

Country Status (11)

Country Link
US (1) US5741713A (da)
EP (1) EP0839152B1 (da)
JP (1) JPH11509086A (da)
AT (1) ATE214396T1 (da)
AU (1) AU6180696A (da)
CA (1) CA2225313A1 (da)
DE (1) DE69619825T2 (da)
DK (1) DK0839152T3 (da)
ES (1) ES2174075T3 (da)
PT (1) PT839152E (da)
WO (1) WO1997000887A1 (da)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055825A1 (en) * 1998-04-30 1999-11-04 Mirus Corporation A process of making a compound by forming a polymer from a template drug
WO2001044828A1 (en) * 1999-12-17 2001-06-21 Maxygen, Inc. Methods for parallel detection of compositions having desired characteristics by means of mri spectroscopy
JP5305553B2 (ja) 2000-10-12 2013-10-02 ユニバーシティー オブ ロチェスター 癌細胞の増殖を阻害する組成物
US7367155B2 (en) 2000-12-20 2008-05-06 Monsanto Technology Llc Apparatus and methods for analyzing and improving agricultural products
EP1572168B1 (en) 2002-02-06 2010-05-26 Vicor Technologies, Inc. Anti-infarction molecules
EP1534729A2 (en) * 2002-02-26 2005-06-01 University of Utah Research Foundation Variants of nedd4l associated with hypertension and viral budding
EP1499545B1 (en) 2002-04-04 2007-12-12 Monsanto Technology LLC Automated picking, weighing and sorting system for particulate matter
US20050287648A1 (en) 2002-08-05 2005-12-29 University Of Rochester Protein Transducing Domain/Deaminase Chimeric Proteins, Related Compounds, and Uses Thereof
US20040214232A1 (en) * 2002-08-16 2004-10-28 Burke Martin D. Generation of skeletal diversity within a combinatorial library
EP1540741B1 (en) 2002-09-05 2014-10-29 Nanosys, Inc. Nanostructure and nanocomposite based compositions and photovoltaic devices
US7600642B2 (en) 2003-09-23 2009-10-13 Monsanto Technology, Llc High throughput automated seed analysis system
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
MX2007002307A (es) 2004-08-26 2007-04-16 Monsanto Technology Llc Prueba automatizada de semillas.
US8076090B2 (en) 2005-04-05 2011-12-13 Corning Incorporated Label free biosensors and cells
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
WO2006127020A1 (en) 2005-05-19 2006-11-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention FUNCTIONAL EPITOPES OF STREPTOCOCCUS PNEUMONIAE PsaA ANTIGEN AND USES THEREOF
ES2909600T3 (es) 2005-06-07 2022-05-09 Dsm Nutritional Products Ag Microorganismos eucarióticos para producir lípidos y antioxidantes
EP2395076A1 (en) 2005-10-14 2011-12-14 MUSC Foundation For Research Development Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy
US8080534B2 (en) 2005-10-14 2011-12-20 Phigenix, Inc Targeting PAX2 for the treatment of breast cancer
US8399201B2 (en) * 2005-10-31 2013-03-19 Janssen Pharmaceutica N.V. Polypeptide complex of TRPM8 and calmodulin and its uses thereof
US8028469B2 (en) 2006-03-02 2011-10-04 Monsanto Technology Llc Automated high-throughput seed sampler and methods of sampling, testing and bulking seeds
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
GB0605584D0 (en) * 2006-03-20 2006-04-26 Olink Ab Method for analyte detection using proximity probes
CN101505883B (zh) 2006-06-28 2014-03-12 孟山都技术有限公司 小物体分类系统和方法
US9023616B2 (en) * 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
EP2066812A4 (en) 2006-09-21 2010-04-28 Univ Rochester COMPOSITIONS AND METHODS RELATED TO PROTEIN SHIFT THERAPY FOR MYOTONE DYSTROPHY
WO2008136852A2 (en) 2006-11-01 2008-11-13 University Of Rochester Methods and compositions related to the structure and function of apobec3g
US20100129358A1 (en) 2006-12-22 2010-05-27 University Of Utah Research Foundation Method of detecting ocular diseases and pathologic conditions and treatment of same
JP2010514839A (ja) 2007-01-03 2010-05-06 バーナム インスティテュート フォー メディカル リサーチ クロット結合化合物に関連する方法および組成物
WO2008098182A1 (en) 2007-02-08 2008-08-14 University Of Utah Research Foundation Methods and compositions related to inhibition of viral entry
BRPI0811990A2 (pt) 2007-05-31 2014-09-23 Monsanto Technology Llc Separador de semente
PT2192946T (pt) 2007-09-25 2022-11-17 Otsuka Pharma Co Ltd Dispositivo no corpo com amplificação de sinal dipolo virtual
WO2010027641A2 (en) * 2008-08-15 2010-03-11 Georgetown University Na channels, disease, and related assays and compositions
US20120070443A1 (en) 2008-12-02 2012-03-22 University Of Utah Research Foundation Pde1 as a target therapeutic in heart disease
CA2745839C (en) 2008-12-05 2017-09-19 C2N Diagnostics Methods for measuring concentrations of biomolecules
SG10201810784SA (en) 2009-04-28 2018-12-28 Proteus Digital Health Inc Highly Reliable Ingestible Event Markers And Methods For Using The Same
US20120149663A1 (en) 2009-08-18 2012-06-14 Georgetown University Boronic acid compositions and methods related to cancer
JP2013507365A (ja) 2009-10-07 2013-03-04 サンフォード−バーナム メディカル リサーチ インスティテュート 血餅結合脂質化合物に関する方法および組成物
EP2512497A1 (en) 2009-12-18 2012-10-24 Sanford-Burnham Medical Research Institute Methods and compositions related to clot-binding compounds
GB201004292D0 (en) * 2010-03-15 2010-04-28 Olink Ab Assay for localised detection of analytes
GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
US20140323392A1 (en) 2011-03-28 2014-10-30 University Of Utah Research Foundation Methods and compositions related to inhibition of viral entry
PE20141562A1 (es) 2011-10-14 2014-11-12 Genentech Inc Anticuerpos anti-htra1 y metodos de uso
AU2012345902A1 (en) * 2011-12-02 2014-06-26 C2N Diagnostics Methods for measuring concentrations of biomolecules
GB201201547D0 (en) 2012-01-30 2012-03-14 Olink Ab Method and product
WO2014139979A1 (en) 2013-03-12 2014-09-18 Ventana Medical Systems, Inc. Quantum dot in situ hybridization
DK2971064T3 (da) 2013-03-12 2019-12-16 Ventana Med Syst Inc Nærhedsassay til in situ-påvisning af mål
AU2014229307B2 (en) 2013-03-13 2017-08-31 Dsm Nutritional Products Ag Engineering microorganisms
CN107003323B (zh) 2014-11-25 2019-06-04 文塔纳医疗系统公司 使用化学连接和半抗原转移的邻近测定法
GB201518655D0 (en) 2015-10-21 2015-12-02 Olink Ab Method for generating proximity probes
BR112018007703A2 (pt) 2015-10-30 2018-11-06 Genentech Inc anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
US12025615B2 (en) 2017-09-15 2024-07-02 Arizona Board Of Regents On Behalf Of Arizona State University Methods of classifying response to immunotherapy for cancer
MX2020006150A (es) 2017-12-15 2020-11-11 Flagship Pioneering Innovations Vi Llc Composiciones que comprenden polirribonucleotidos circulares y usos de las mismas.
MA55082A (fr) 2019-03-01 2022-01-05 Flagship Pioneering Innovations Vi Llc Compositions, procédés, et kits pour l'administration de polyribonucléotides
JP7618577B2 (ja) 2019-03-25 2025-01-21 フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー 修飾環状ポリリボヌクレオチドを含む組成物及びその使用
US20220257794A1 (en) 2019-06-14 2022-08-18 Flagship Pioneering Innovations Vi, Llc Circular rnas for cellular therapy
AU2020296190A1 (en) 2019-06-19 2022-01-06 Flagship Pioneering Innovations Vi, Llc Methods of dosing circular polyribonucleotides
EP4038222A4 (en) 2019-10-02 2023-10-18 Arizona Board of Regents on behalf of Arizona State University Methods and compositions for identifying neoantigens for use in treating and preventing cancer
EP4096681A1 (en) 2020-01-29 2022-12-07 Flagship Pioneering Innovations VI, LLC Delivery of compositions comprising circular polyribonucleotides
BR112022025113A2 (pt) 2020-06-30 2022-12-27 Monsanto Technology Llc Sistemas automatizados para uso em separação de pequenos objetos, e métodos relacionados
US12653400B2 (en) 2021-01-29 2026-06-16 The Regents Of The University Of California Implantable imagers for in vivo imaging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2102984T3 (es) * 1989-06-14 1997-08-16 Martek Corp Medios para el crecimiento de celulas y procedimiento para preparar los mismos.
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
HUT72495A (en) * 1992-10-01 1996-05-28 Cold Spring Harbor Lab Complex combinatorial chemical libraries encoded with tags

Also Published As

Publication number Publication date
AU6180696A (en) 1997-01-22
WO1997000887A1 (en) 1997-01-09
EP0839152A1 (en) 1998-05-06
ES2174075T3 (es) 2002-11-01
ATE214396T1 (de) 2002-03-15
DE69619825T2 (de) 2002-10-10
US5741713A (en) 1998-04-21
DE69619825D1 (de) 2002-04-18
CA2225313A1 (en) 1997-01-09
EP0839152B1 (en) 2002-03-13
JPH11509086A (ja) 1999-08-17
PT839152E (pt) 2002-09-30

Similar Documents

Publication Publication Date Title
PT839152E (pt) Bibliotecas combinatorias de compostos bioquimicos marcados e metodos para as produzir.
DK0933082T3 (da) Fremgangsmåde til manipulation af celledifferentiering
ATE343791T1 (de) Verfahren zur sichtung einer bibliothek von chemischen verbindungen
ATE261581T1 (de) Verfahren zum entwerfen und herstellung von zielmolekulbindenden liganden
DK0751950T3 (da) Fremgangsmåde til identifikation af elementer af kombinatoriske biblioteker
WO2001094946A3 (en) Microarrays for performing proteomic analyses
WO2003061570A3 (en) Engineered binding proteins
ATE355312T1 (de) Verfahren zur herstellung polymerer festphasenträger
LU91759I2 (fr) Denosumab et ses dérivés pharmaceutique acceptables (PROLIA®)
ZA200106630B (en) Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof.
ATE216777T1 (de) Affinitäts-selektion von liganden mittels massenspektroskopie
GB9318612D0 (en) An assay
ATE545019T1 (de) Mikrofluidisches extraktionsverfahren
DE69628194D1 (de) Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden
JPH1025299A (ja) 整列ペプチド、及びそれを用いたタンパク質の結合・相互作用部位検出方法
DK0870197T3 (da) Anvendelse af nuclear magnetisk resonans til design af ligander rettet mod biomolekyler
WO1997035194A3 (en) Enantiomeric screening process, and compositions therefor
WO2001050127A3 (en) Screening using biological target molecules with metal-ion binding sites
IL143045A0 (en) A method for determining a mimotope sequence
WO2002014858A3 (de) Verfahren zur herstellung und ermittlung geeigneter effektoren von zielmolekülen mit substanzbibliotheken
ATE408816T1 (de) Verfahren zur bestimmung sekundärer molekülmodifikationen unter verwendung von arrays
ITRM930391A0 (it) Metodologia per la selezione di sequenze amminoacidiche, che interferiscono con il legame ligando-recettore, mediante librerie combinatoriali di peptidi sintetici sintetici multimerici.
Zapala Rozdzial mieszaniny wieloskladnikowej metoda adsorpcyjnej chromatografii cieczowej na przykladzie poreakcyjnej mieszaniny izomerow chloronitrobenzenu.