DK0854146T3 - Substitueret 4-(6-fluor-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridin til behandling af CNS forstyrrelser - Google Patents

Substitueret 4-(6-fluor-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridin til behandling af CNS forstyrrelser

Info

Publication number
DK0854146T3
DK0854146T3 DK98300249T DK98300249T DK0854146T3 DK 0854146 T3 DK0854146 T3 DK 0854146T3 DK 98300249 T DK98300249 T DK 98300249T DK 98300249 T DK98300249 T DK 98300249T DK 0854146 T3 DK0854146 T3 DK 0854146T3
Authority
DK
Denmark
Prior art keywords
tetrahydropyridine
indol
fluoro
substituted
treatment
Prior art date
Application number
DK98300249T
Other languages
English (en)
Inventor
John Fairhurst
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0854146T3 publication Critical patent/DK0854146T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98300249T 1997-01-17 1998-01-14 Substitueret 4-(6-fluor-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridin til behandling af CNS forstyrrelser DK0854146T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9700895.7A GB9700895D0 (en) 1997-01-17 1997-01-17 Pharmaceutical compounds
EP98300249A EP0854146B1 (en) 1997-01-17 1998-01-14 Substituted 4-(6-fluoro-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders

Publications (1)

Publication Number Publication Date
DK0854146T3 true DK0854146T3 (da) 2000-06-05

Family

ID=10806121

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98300249T DK0854146T3 (da) 1997-01-17 1998-01-14 Substitueret 4-(6-fluor-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridin til behandling af CNS forstyrrelser

Country Status (29)

Country Link
US (1) US20010053783A1 (da)
EP (1) EP0854146B1 (da)
JP (1) JPH10204090A (da)
KR (1) KR20000070221A (da)
AR (1) AR011422A1 (da)
AT (1) ATE190617T1 (da)
AU (1) AU5569298A (da)
CA (1) CA2227132A1 (da)
CZ (1) CZ290318B6 (da)
DE (1) DE69800092T2 (da)
DK (1) DK0854146T3 (da)
EA (1) EA001469B1 (da)
ES (1) ES2144888T3 (da)
GB (1) GB9700895D0 (da)
GR (1) GR3033316T3 (da)
HU (1) HUP0000854A3 (da)
ID (1) ID21920A (da)
IL (1) IL129647A (da)
NO (1) NO993372D0 (da)
NZ (1) NZ335493A (da)
PE (1) PE99399A1 (da)
PL (1) PL334569A1 (da)
PT (1) PT854146E (da)
SI (1) SI0854146T1 (da)
SV (1) SV1998000088A (da)
TR (1) TR199901583T2 (da)
TW (1) TW396156B (da)
WO (1) WO1998031686A1 (da)
ZA (1) ZA98300B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8743098A (en) * 1997-08-22 1999-03-16 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
GB9825413D0 (en) * 1998-11-19 1999-01-13 Lilly Co Eli Pharmaceutical compounds
GB9903784D0 (en) * 1999-02-18 1999-04-14 Lilly Co Eli Pharmaceutical compounds
AR028945A1 (es) * 2000-06-19 2003-05-28 Lundbeck & Co As H Derivados de indol
KR101165996B1 (ko) 2010-04-23 2012-07-18 주식회사 녹십자 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
CN105949190B (zh) * 2016-07-04 2018-06-29 烟台凯博医药科技有限公司 一种制备1，8-萘啶及衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
DK158590D0 (da) * 1990-07-02 1990-07-02 Lundbeck & Co As H Indolderivater
FR2675801A1 (fr) * 1991-04-24 1992-10-30 Rhone Poulenc Rorer Sa Piperidines, leur preparation et les medicaments les contenant.
DE19500689A1 (de) * 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
PT854146E (pt) 2000-08-31
EA199900667A1 (ru) 2000-02-28
CA2227132A1 (en) 1998-07-17
ES2144888T3 (es) 2000-06-16
HUP0000854A2 (hu) 2000-11-28
SI0854146T1 (en) 2000-10-31
SV1998000088A (es) 2000-10-10
AU5569298A (en) 1998-08-07
EA001469B1 (ru) 2001-04-23
NZ335493A (en) 2000-09-29
PE99399A1 (es) 1999-11-11
NO993372L (no) 1999-07-08
DE69800092T2 (de) 2000-09-14
CZ290318B6 (cs) 2002-07-17
AR011422A1 (es) 2000-08-16
WO1998031686A1 (en) 1998-07-23
ID21920A (id) 1999-08-12
NO993372D0 (no) 1999-07-08
DE69800092D1 (de) 2000-04-20
GB9700895D0 (en) 1997-03-05
JPH10204090A (ja) 1998-08-04
US20010053783A1 (en) 2001-12-20
EP0854146B1 (en) 2000-03-15
ZA98300B (en) 1998-09-10
CZ151099A3 (cs) 1999-09-15
HUP0000854A3 (en) 2002-06-28
TW396156B (en) 2000-07-01
ATE190617T1 (de) 2000-04-15
EP0854146A1 (en) 1998-07-22
PL334569A1 (en) 2000-03-13
TR199901583T2 (xx) 1999-11-22
KR20000070221A (ko) 2000-11-25
IL129647A0 (en) 2000-02-29
IL129647A (en) 2002-02-10
GR3033316T3 (en) 2000-09-29

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