DK0865281T3 - Naphthylsubstituerede benzimidazolderivater som antikoagulerende midler - Google Patents

Naphthylsubstituerede benzimidazolderivater som antikoagulerende midler

Info

Publication number: DK0865281T3
Authority: DK; Denmark
Prior art keywords: anticoagulants; naphthyl; benzimidazole derivatives; substituted benzimidazole; substituted
Prior art date: 1995-12-08

Application number

DK96944123T

Other languages

Danish (da)

English (en)

Inventor

Damian O Arnaiz

Brian D Griedel

Stephen T Sakata

Kenneth J Shaw

Zuchan Zhao

Original Assignee

Berlex Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-08

Filing date

1996-12-05

Publication date

2002-07-29

1996-12-05 Application filed by Berlex Lab filed Critical Berlex Lab

2002-07-29 Application granted granted Critical

2002-07-29 Publication of DK0865281T3 publication Critical patent/DK0865281T3/da

Links

239000003146 anticoagulant agent Substances 0.000 title abstract 2
229940127219 anticoagulant drug Drugs 0.000 title abstract 2
229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Preventing Corrosion Or Incrustation Of Metals (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)

DK96944123T 1995-12-08 1996-12-05 Naphthylsubstituerede benzimidazolderivater som antikoagulerende midler DK0865281T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/570,057 US5849759A (en)	1995-12-08	1995-12-08	Naphthyl-substituted benzimidazole derivatives as anti-coagulants
PCT/IB1996/001496 WO1997021437A1 (en)	1995-12-08	1996-12-05	Naphthyl-substituted benzimidazole derivatives as anticoagulants

Publications (1)

Publication Number	Publication Date
DK0865281T3 true DK0865281T3 (da)	2002-07-29

Family

ID=24278023

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96944123T DK0865281T3 (da)	1995-12-08	1996-12-05	Naphthylsubstituerede benzimidazolderivater som antikoagulerende midler

Country Status (22)

Country	Link
US (1)	US5849759A (es)
EP (1)	EP0865281B1 (es)
JP (1)	JP2000502082A (es)
KR (1)	KR19990071974A (es)
CN (1)	CN1110305C (es)
AT (1)	ATE215371T1 (es)
CZ (1)	CZ177698A3 (es)
DE (1)	DE69620443T2 (es)
DK (1)	DK0865281T3 (es)
ES (1)	ES2175179T3 (es)
HU (1)	HUP9904066A3 (es)
IL (1)	IL124537A (es)
MX (1)	MX9804597A (es)
NO (1)	NO312673B1 (es)
NZ (1)	NZ325449A (es)
PL (1)	PL327169A1 (es)
PT (1)	PT865281E (es)
RU (1)	RU98112597A (es)
SK (1)	SK282767B6 (es)
UA (1)	UA49869C2 (es)
WO (1)	WO1997021437A1 (es)
ZA (1)	ZA9610315B (es)

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PE27997A1 (es) *	1994-04-29	1997-09-20	Lilly Co Eli	Antagonistas de receptores de taquicininas

1995
- 1995-12-08 US US08/570,057 patent/US5849759A/en not_active Expired - Fee Related
1996
- 1996-12-05 RU RU98112597/04A patent/RU98112597A/ru not_active Application Discontinuation
- 1996-12-05 EP EP96944123A patent/EP0865281B1/en not_active Expired - Lifetime
- 1996-12-05 PT PT96944123T patent/PT865281E/pt unknown
- 1996-12-05 NZ NZ325449A patent/NZ325449A/xx unknown
- 1996-12-05 JP JP9521899A patent/JP2000502082A/ja not_active Ceased
- 1996-12-05 WO PCT/IB1996/001496 patent/WO1997021437A1/en not_active Ceased
- 1996-12-05 AT AT96944123T patent/ATE215371T1/de not_active IP Right Cessation
- 1996-12-05 CN CN96199921A patent/CN1110305C/zh not_active Expired - Fee Related
- 1996-12-05 IL IL12453796A patent/IL124537A/en not_active IP Right Cessation
- 1996-12-05 HU HU9904066A patent/HUP9904066A3/hu unknown
- 1996-12-05 MX MX9804597A patent/MX9804597A/es not_active IP Right Cessation
- 1996-12-05 SK SK746-98A patent/SK282767B6/sk unknown
- 1996-12-05 ES ES96944123T patent/ES2175179T3/es not_active Expired - Lifetime
- 1996-12-05 CZ CZ981776A patent/CZ177698A3/cs unknown
- 1996-12-05 KR KR1019980704265A patent/KR19990071974A/ko not_active Ceased
- 1996-12-05 PL PL96327169A patent/PL327169A1/xx unknown
- 1996-12-05 DE DE69620443T patent/DE69620443T2/de not_active Expired - Fee Related
- 1996-12-05 DK DK96944123T patent/DK0865281T3/da active
- 1996-12-05 UA UA98073607A patent/UA49869C2/uk unknown
- 1996-12-06 ZA ZA9610315A patent/ZA9610315B/xx unknown
1998
- 1998-06-05 NO NO19982606A patent/NO312673B1/no unknown

Also Published As

Publication number	Publication date
HK1018208A1 (en)	1999-12-17
HUP9904066A2 (hu)	2000-03-28
CN1110305C (zh)	2003-06-04
ATE215371T1 (de)	2002-04-15
HUP9904066A3 (en)	2001-11-28
ZA9610315B (en)	1997-06-17
WO1997021437A1 (en)	1997-06-19
DE69620443T2 (de)	2002-11-28
UA49869C2 (uk)	2002-10-15
EP0865281A1 (en)	1998-09-23
IL124537A0 (en)	1998-12-06
SK282767B6 (sk)	2002-12-03
CZ177698A3 (cs)	1998-09-16
NO312673B1 (no)	2002-06-17
PL327169A1 (en)	1998-11-23
KR19990071974A (ko)	1999-09-27
PT865281E (pt)	2002-09-30
US5849759A (en)	1998-12-15
MX9804597A (es)	1998-10-31
JP2000502082A (ja)	2000-02-22
SK74698A3 (en)	1998-12-02
AU1395697A (en)	1997-07-03
DE69620443D1 (de)	2002-05-08
NO982606D0 (no)	1998-06-05
AU700894B2 (en)	1999-01-14
RU98112597A (ru)	2000-10-20
NO982606L (no)	1998-08-10
NZ325449A (en)	2000-01-28
ES2175179T3 (es)	2002-11-16
EP0865281A4 (en)	1999-07-28
EP0865281B1 (en)	2002-04-03
CN1209062A (zh)	1999-02-24
IL124537A (en)	2002-04-21

Publication	Publication Date	Title
NO982606D0 (no)	1998-06-05	Naftylsubstituerte benzimidazolderivater som antikoagulanter
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
KR950700894A (ko)	1995-02-20	탁솔 유도체(Taxol derivatives)
DK0868424T3 (da)	2003-05-19	4-Pyrimidinyl- eller 4-pyrazinyl-piperazinyl-phenyloxazolidinonderivater, fremstilling deraf og anvendelse deraf som antibakterielle midler
TR199700844T1 (xx)	1998-01-21	Pirazolil-Benzoil T�revleri.
DK1040108T3 (da)	2004-05-24	Orthoanthranilamidderivater som antikoagulanter
ES2097174T3 (es)	1997-04-01	Derivados de la 2-ciclohexan-1-il amina.
ES2187660T3 (es)	2003-06-16	Derivados de rapamicina.
DE69705300D1 (de)	2001-07-26	Cyclopropylalkansäurederivate
TR199800011T1 (xx)	1998-04-21	Benzo$g] kuinolin t�revleri
NO963370D0 (no)	1996-08-13	Nye mercaptoacetylamido-1,3,4,5-tetrahydro-benzo[cÅazepin-3-on-disulfidderivater som er anvendbare som inhibitorer av enkefalinase og ACE
DE60317884T8 (de)	2009-06-04	Natriumkanalblocker
LU92263I2 (fr)	2013-10-07	Imépitoïne et ses dérivés pharmaceutiquement acceptables (PEXION)
TR200001452T2 (tr)	2004-12-21	Bifenilamidin türevleri.
TR199700206A2 (xx)	1997-10-21	Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
BR0210746A (pt)	2004-07-20	Derivados de 6-'2-(fosfonometóxi)alcóxi-pirimidina tendo atividade antiviral
ATE117677T1 (de)	1995-02-15	Indolderivate.
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
DK0777653T3 (da)	2001-10-08	Dihydropyridinderivater som bradykininantagonister
HRP20010885B1 (en)	2010-07-31	Ethanesulfonyl-piperidine derivatives
DK0660822T3 (da)	1997-08-25	Cykliske benzylamino-, benzylamido- og benzylimidoderivater som antipsykotiske midler
EP0702014A4 (en)	1996-08-07	DC-89 DERIVATIVES
EA199900684A1 (ru)	2000-04-24	Производные иминоазаантрациклинона для лечения амилоидоза
TW346483B (en)	1998-12-01	Benzene derivatives
ES2103675A1 (es)	1997-09-16	Nuevas piperidinas sustituidas.