DK0882725T3 - Quinoloncarboxylsyrederivater eller deres salte - Google Patents
Quinoloncarboxylsyrederivater eller deres salteInfo
- Publication number
- DK0882725T3 DK0882725T3 DK97902618T DK97902618T DK0882725T3 DK 0882725 T3 DK0882725 T3 DK 0882725T3 DK 97902618 T DK97902618 T DK 97902618T DK 97902618 T DK97902618 T DK 97902618T DK 0882725 T3 DK0882725 T3 DK 0882725T3
- Authority
- DK
- Denmark
- Prior art keywords
- salts
- acid derivatives
- optionally substituted
- carboxylic acid
- halogeno
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- XOQQVKDBGLYPGH-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carboxylic acid Chemical class C1=CC=C2NC(=O)C(C(=O)O)=CC2=C1 XOQQVKDBGLYPGH-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4793696 | 1996-02-09 | ||
| PCT/JP1997/000317 WO1997029102A1 (en) | 1996-02-09 | 1997-02-07 | Quinolonecarboxylic acid derivatives or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0882725T3 true DK0882725T3 (da) | 2003-01-13 |
Family
ID=12789268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97902618T DK0882725T3 (da) | 1996-02-09 | 1997-02-07 | Quinoloncarboxylsyrederivater eller deres salte |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6025370A (da) |
| EP (1) | EP0882725B1 (da) |
| KR (1) | KR100276477B1 (da) |
| CN (2) | CN100395244C (da) |
| AT (1) | ATE229950T1 (da) |
| AU (1) | AU711914B2 (da) |
| CA (1) | CA2242242C (da) |
| DE (1) | DE69717970T2 (da) |
| DK (1) | DK0882725T3 (da) |
| ES (1) | ES2188890T3 (da) |
| HK (1) | HK1039118B (da) |
| HU (1) | HU228567B1 (da) |
| IL (1) | IL124944A (da) |
| NO (1) | NO316666B1 (da) |
| NZ (1) | NZ330775A (da) |
| PT (1) | PT882725E (da) |
| WO (1) | WO1997029102A1 (da) |
| ZA (1) | ZA971023B (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2321042T3 (es) | 1997-09-15 | 2009-06-01 | THE PROCTER & GAMBLE COMPANY | Quinolonas antimicrobianas, composiciones y usos de las mismas. |
| US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
| NZ504084A (en) * | 1997-10-27 | 2003-02-28 | Toyama Chemical Co Ltd | Processes for producing 7-isoindolinequinolonecarboxylic derivatives and its intermediates, as well as salts of 7-isoindolinequinolonecarboxylic acid derivatives, its hydrates and composition comprising the same as active ingredient |
| JP3281872B2 (ja) | 1998-03-20 | 2002-05-13 | 富山化学工業株式会社 | ７−イソインドリン−３−キノリンカルボン酸の塩、その水和物およびそれらを活性成分とする組成物 |
| BRPI9909456B8 (pt) * | 1998-04-06 | 2021-07-06 | Toyama Chemical Co Ltd | Ácido quinolonecarboxílico ou sais dos mesmos |
| JP4499846B2 (ja) * | 1998-05-07 | 2010-07-07 | 富山化学工業株式会社 | ７−イソインドリン−キノロンカルボン酸誘導体の製造法並びにイソインドリン−５−ボロン酸誘導体の製造法 |
| JP4549461B2 (ja) * | 1998-08-31 | 2010-09-22 | 富山化学工業株式会社 | ７−ブロモ−キノロンカルボン酸誘導体の製造法 |
| JP2000229946A (ja) * | 1998-12-10 | 2000-08-22 | Toyama Chem Co Ltd | キノロンカルボン酸の製造法およびその中間体 |
| CA2367373C (en) | 1999-03-17 | 2011-09-20 | Daiichi Pharmaceutical Co., Ltd. | Medicinal compositions |
| WO2003077842A2 (en) * | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | Palatable oral suspension and method |
| WO2004113321A1 (ja) * | 2003-06-19 | 2004-12-29 | Daiichi Pharmaceutical Co., Ltd. | 選択的なアミノ置換基導入法 |
| DE10337191A1 (de) * | 2003-08-13 | 2005-03-17 | Bayer Healthcare Ag | Neue Verwendung von Chinolon-Antibiotika |
| KR100981351B1 (ko) * | 2003-10-29 | 2010-09-10 | 주식회사 엘지생명과학 | 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법 |
| US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| KR101408393B1 (ko) * | 2005-03-03 | 2014-06-17 | 제이엔씨 주식회사 | 클로로플루오로벤젠 액정 화합물, 액정 조성물, 및 액정표시 소자 |
| EP1999106B1 (en) | 2006-03-28 | 2012-06-27 | TaiGen Biotechnology Co., Ltd. | A hydride reduction process for preparing quinolone intermediates |
| WO2007110835A2 (en) | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | A coupling process for preparing quinolone intermediates |
| US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
| CN101298418B (zh) * | 2008-06-13 | 2010-12-15 | 江苏康鹏农化有限公司 | 3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法 |
| CN102212056A (zh) * | 2010-04-09 | 2011-10-12 | 山东轩竹医药科技有限公司 | 新的双环喹诺酮类化合物 |
| WO2013121439A2 (en) * | 2012-02-15 | 2013-08-22 | Glenmark Generics Limited | Process for garenoxacin mesylate |
| CA2904387C (en) | 2013-03-15 | 2021-12-07 | Melinta Therapeutics, Inc. | Methods of treating infections in overweight and obese patients using antibiotics |
| GB201516614D0 (en) * | 2015-09-18 | 2015-11-04 | Redx Pharma Plc | Antibacterial compounds |
| CN105837555B (zh) * | 2016-03-31 | 2019-01-25 | 南京华威医药科技集团有限公司 | 加雷沙星及其中间体制备方法 |
| CN111620901B (zh) * | 2020-06-08 | 2023-03-21 | 蚌埠医学院第二附属医院 | 一种含硅氧烷基的氟喹诺酮化合物、其制备方法及用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6199835A (ja) * | 1984-10-22 | 1986-05-17 | Shimadzu Corp | 振動試験機の波形補正装置 |
| MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
| RU2049777C1 (ru) * | 1989-08-16 | 1995-12-10 | Пфайзер Инк. | Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения |
| EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
| JPH07300472A (ja) * | 1992-12-28 | 1995-11-14 | Korea Res Inst Chem Technol | 新規キノロンカルボン酸誘導体およびその製造方法 |
| JPH06199835A (ja) * | 1993-01-08 | 1994-07-19 | Hokuriku Seiyaku Co Ltd | ８−ジフルオロメトキシキノリン−３−カルボン酸誘導体 |
| DE4301246A1 (de) * | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
| JPH0848629A (ja) * | 1994-08-08 | 1996-02-20 | Dainippon Pharmaceut Co Ltd | ピリドンカルボン酸誘導体およびそれを有効成分とする抗ピロリ菌剤 |
| ATE245638T1 (de) * | 1994-08-12 | 2003-08-15 | Toyama Chemical Co Ltd | Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze |
-
1997
- 1997-02-07 WO PCT/JP1997/000317 patent/WO1997029102A1/ja not_active Ceased
- 1997-02-07 NZ NZ330775A patent/NZ330775A/xx not_active IP Right Cessation
- 1997-02-07 CA CA002242242A patent/CA2242242C/en not_active Expired - Lifetime
- 1997-02-07 US US09/125,016 patent/US6025370A/en not_active Expired - Lifetime
- 1997-02-07 CN CNB011012323A patent/CN100395244C/zh not_active Expired - Lifetime
- 1997-02-07 EP EP97902618A patent/EP0882725B1/en not_active Expired - Lifetime
- 1997-02-07 IL IL12494497A patent/IL124944A/xx not_active IP Right Cessation
- 1997-02-07 PT PT97902618T patent/PT882725E/pt unknown
- 1997-02-07 ES ES97902618T patent/ES2188890T3/es not_active Expired - Lifetime
- 1997-02-07 KR KR1019980706138A patent/KR100276477B1/ko not_active Expired - Lifetime
- 1997-02-07 AT AT97902618T patent/ATE229950T1/de active
- 1997-02-07 CN CN97192130A patent/CN1100053C/zh not_active Expired - Lifetime
- 1997-02-07 AU AU16701/97A patent/AU711914B2/en not_active Expired
- 1997-02-07 DK DK97902618T patent/DK0882725T3/da active
- 1997-02-07 DE DE69717970T patent/DE69717970T2/de not_active Expired - Lifetime
- 1997-02-07 HU HU9901966A patent/HU228567B1/hu unknown
- 1997-02-07 ZA ZA9701023A patent/ZA971023B/xx unknown
-
1998
- 1998-08-07 NO NO19983625A patent/NO316666B1/no not_active IP Right Cessation
-
2002
- 2002-01-16 HK HK02100336.1A patent/HK1039118B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1039118B (zh) | 2009-01-30 |
| AU1670197A (en) | 1997-08-28 |
| DE69717970T2 (de) | 2003-04-30 |
| EP0882725A4 (en) | 1999-05-06 |
| US6025370A (en) | 2000-02-15 |
| CA2242242C (en) | 2001-08-07 |
| DE69717970D1 (de) | 2003-01-30 |
| EP0882725A1 (en) | 1998-12-09 |
| KR19990082406A (ko) | 1999-11-25 |
| ATE229950T1 (de) | 2003-01-15 |
| AU711914B2 (en) | 1999-10-21 |
| NZ330775A (en) | 1999-08-30 |
| ZA971023B (en) | 1997-09-25 |
| KR100276477B1 (ko) | 2000-12-15 |
| NO983625D0 (no) | 1998-08-07 |
| PT882725E (pt) | 2003-04-30 |
| CA2242242A1 (en) | 1997-08-14 |
| IL124944A (en) | 2003-06-24 |
| CN1210533A (zh) | 1999-03-10 |
| ES2188890T3 (es) | 2003-07-01 |
| IL124944A0 (en) | 1999-01-26 |
| HUP9901966A2 (hu) | 1999-09-28 |
| HU228567B1 (en) | 2013-04-29 |
| NO983625L (no) | 1998-08-07 |
| EP0882725B1 (en) | 2002-12-18 |
| WO1997029102A1 (en) | 1997-08-14 |
| HK1039118A1 (zh) | 2002-04-12 |
| HUP9901966A3 (en) | 2002-01-28 |
| CN1100053C (zh) | 2003-01-29 |
| NO316666B1 (no) | 2004-03-29 |
| CN100395244C (zh) | 2008-06-18 |
| CN1314355A (zh) | 2001-09-26 |
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