ATE229950T1 - Chinolin carbonsaure-derivate und ihre salze - Google Patents

Chinolin carbonsaure-derivate und ihre salze

Info

Publication number: ATE229950T1
Authority: AT; Austria
Prior art keywords: salts; acid derivatives; optionally substituted; carbonic acid; halogeno
Prior art date: 1996-02-09

Application number

AT97902618T

Other languages

English (en)

Inventor

Yozo Todo

Kazuya Hayashi

Masahiro Takahata

Yasuo Watanabe

Hirokazu Narita

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-09

Filing date

1997-02-07

Publication date

2003-01-15

1997-02-07 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

2003-01-15 Application granted granted Critical

2003-01-15 Publication of ATE229950T1 publication Critical patent/ATE229950T1/de

Links

150000003839 salts Chemical class 0.000 title abstract 2
CIRQMILQJVWYKN-UHFFFAOYSA-N carbonic acid;quinoline Chemical class OC(O)=O.N1=CC=CC2=CC=CC=C21 CIRQMILQJVWYKN-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Indole Compounds (AREA)

AT97902618T 1996-02-09 1997-02-07 Chinolin carbonsaure-derivate und ihre salze ATE229950T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP4793696		1996-02-09
PCT/JP1997/000317 WO1997029102A1 (en)	1996-02-09	1997-02-07	Quinolonecarboxylic acid derivatives or salts thereof

Publications (1)

Publication Number	Publication Date
ATE229950T1 true ATE229950T1 (de)	2003-01-15

Family

ID=12789268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97902618T ATE229950T1 (de)	1996-02-09	1997-02-07	Chinolin carbonsaure-derivate und ihre salze

Country Status (18)

Country	Link
US (1)	US6025370A (de)
EP (1)	EP0882725B1 (de)
KR (1)	KR100276477B1 (de)
CN (2)	CN1100053C (de)
AT (1)	ATE229950T1 (de)
AU (1)	AU711914B2 (de)
CA (1)	CA2242242C (de)
DE (1)	DE69717970T2 (de)
DK (1)	DK0882725T3 (de)
ES (1)	ES2188890T3 (de)
HK (1)	HK1039118B (de)
HU (1)	HU228567B1 (de)
IL (1)	IL124944A (de)
NO (1)	NO316666B1 (de)
NZ (1)	NZ330775A (de)
PT (1)	PT882725E (de)
WO (1)	WO1997029102A1 (de)
ZA (1)	ZA971023B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK286420B6 (sk)	1997-09-15	2008-09-05	The Procter & Gamble Company	Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
US6387928B1 (en)	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
AU750760B2 (en) *	1997-10-27	2002-07-25	Toyama Chemical Co. Ltd.	Processes for producing 7-isoindolinequinolonecarboxylic derivatives and intermediates therefor, salts of 7-isoindolinequinolonecarboxylic acids, hydrates thereof, and composition containing the same as active ingredient
JP3281872B2 (ja)	1998-03-20	2002-05-13	富山化学工業株式会社	７−イソインドリン−３−キノリンカルボン酸の塩、その水和物およびそれらを活性成分とする組成物
BRPI9909456B8 (pt) *	1998-04-06	2021-07-06	Toyama Chemical Co Ltd	Ácido quinolonecarboxílico ou sais dos mesmos
JP4499846B2 (ja) *	1998-05-07	2010-07-07	富山化学工業株式会社	７−イソインドリン−キノロンカルボン酸誘導体の製造法並びにイソインドリン−５−ボロン酸誘導体の製造法
JP4549461B2 (ja) *	1998-08-31	2010-09-22	富山化学工業株式会社	７−ブロモ−キノロンカルボン酸誘導体の製造法
JP2000229946A (ja) *	1998-12-10	2000-08-22	Toyama Chem Co Ltd	キノロンカルボン酸の製造法およびその中間体
AU3192700A (en)	1999-03-17	2000-10-04	Daiichi Pharmaceutical Co., Ltd.	Medicinal compositions
WO2003077842A2 (en) *	2002-03-12	2003-09-25	Bristol-Myers Squibb Company	Palatable oral suspension and method
EP1634879A4 (de) *	2003-06-19	2007-09-05	Daiichi Seiyaku Co	Verfahren zur selektiven einführung eines aminosubstituenten
DE10337191A1 (de) *	2003-08-13	2005-03-17	Bayer Healthcare Ag	Neue Verwendung von Chinolon-Antibiotika
KR100981351B1 (ko) *	2003-10-29	2010-09-10	주식회사 엘지생명과학	7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법
US20090156577A1 (en) *	2004-09-09	2009-06-18	Benjamin Davis	7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
JP4941290B2 (ja) *	2005-03-03	2012-05-30	Ｊｎｃ株式会社	クロロフルオロベンゼン系液晶性化合物、液晶組成物および液晶表示素子
MX2008012488A (es)	2006-03-28	2008-10-10	Procter & Gamble	Un proceso de acoplamiento para preparar intermedios de quinolona.
CA2647457C (en)	2006-03-28	2011-05-24	The Procter & Gamble Company	A hydride reduction process for preparing quinolone intermediates
US7902227B2 (en) *	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN101298418B (zh) *	2008-06-13	2010-12-15	江苏康鹏农化有限公司	3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法
CN102212056A (zh) *	2010-04-09	2011-10-12	山东轩竹医药科技有限公司	新的双环喹诺酮类化合物
WO2013121439A2 (en) *	2012-02-15	2013-08-22	Glenmark Generics Limited	Process for garenoxacin mesylate
KR102237887B1 (ko)	2013-03-15	2021-04-07	멜린타 서브시디어리 코프.	항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법
GB201516614D0 (en) *	2015-09-18	2015-11-04	Redx Pharma Plc	Antibacterial compounds
CN105837555B (zh) *	2016-03-31	2019-01-25	南京华威医药科技集团有限公司	加雷沙星及其中间体制备方法
CN111620901B (zh) *	2020-06-08	2023-03-21	蚌埠医学院第二附属医院	一种含硅氧烷基的氟喹诺酮化合物、其制备方法及用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6199835A (ja) *	1984-10-22	1986-05-17	Shimadzu Corp	振動試験機の波形補正装置
IL90062A (en) *	1988-04-27	1994-10-07	Daiichi Seiyaku Co	Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
WO1991002526A1 (en) *	1989-08-16	1991-03-07	Pfizer Inc.	Azabicyclo quinolone carboxylic acids
EG20543A (en) *	1992-10-30	1999-07-31	Procter & Gamble	Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
JPH07300472A (ja) *	1992-12-28	1995-11-14	Korea Res Inst Chem Technol	新規キノロンカルボン酸誘導体およびその製造方法
JPH06199835A (ja) *	1993-01-08	1994-07-19	Hokuriku Seiyaku Co Ltd	８−ジフルオロメトキシキノリン−３−カルボン酸誘導体
DE4301246A1 (de) *	1993-01-19	1994-07-21	Bayer Ag	Chinolon- und Naphthyridoncarbonsäurederivate
JPH0848629A (ja) *	1994-08-08	1996-02-20	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体およびそれを有効成分とする抗ピロリ菌剤
EP0775702B1 (de) *	1994-08-12	2003-07-23	Toyama Chemical Co., Ltd.	Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze

1997
- 1997-02-07 AT AT97902618T patent/ATE229950T1/de active
- 1997-02-07 HU HU9901966A patent/HU228567B1/hu unknown
- 1997-02-07 WO PCT/JP1997/000317 patent/WO1997029102A1/ja not_active Ceased
- 1997-02-07 PT PT97902618T patent/PT882725E/pt unknown
- 1997-02-07 KR KR1019980706138A patent/KR100276477B1/ko not_active Expired - Lifetime
- 1997-02-07 CN CN97192130A patent/CN1100053C/zh not_active Expired - Lifetime
- 1997-02-07 CA CA002242242A patent/CA2242242C/en not_active Expired - Lifetime
- 1997-02-07 IL IL12494497A patent/IL124944A/xx not_active IP Right Cessation
- 1997-02-07 US US09/125,016 patent/US6025370A/en not_active Expired - Lifetime
- 1997-02-07 DK DK97902618T patent/DK0882725T3/da active
- 1997-02-07 CN CNB011012323A patent/CN100395244C/zh not_active Expired - Lifetime
- 1997-02-07 NZ NZ330775A patent/NZ330775A/xx not_active IP Right Cessation
- 1997-02-07 EP EP97902618A patent/EP0882725B1/de not_active Expired - Lifetime
- 1997-02-07 DE DE69717970T patent/DE69717970T2/de not_active Expired - Lifetime
- 1997-02-07 ES ES97902618T patent/ES2188890T3/es not_active Expired - Lifetime
- 1997-02-07 AU AU16701/97A patent/AU711914B2/en not_active Expired
- 1997-02-07 ZA ZA9701023A patent/ZA971023B/xx unknown
1998
- 1998-08-07 NO NO19983625A patent/NO316666B1/no not_active IP Right Cessation
2002
- 2002-01-16 HK HK02100336.1A patent/HK1039118B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL124944A0 (en)	1999-01-26
EP0882725A1 (de)	1998-12-09
KR100276477B1 (ko)	2000-12-15
AU1670197A (en)	1997-08-28
ES2188890T3 (es)	2003-07-01
IL124944A (en)	2003-06-24
NO983625D0 (no)	1998-08-07
NZ330775A (en)	1999-08-30
NO316666B1 (no)	2004-03-29
DE69717970T2 (de)	2003-04-30
CN1210533A (zh)	1999-03-10
ZA971023B (en)	1997-09-25
NO983625L (no)	1998-08-07
EP0882725A4 (de)	1999-05-06
CA2242242A1 (en)	1997-08-14
CN100395244C (zh)	2008-06-18
KR19990082406A (ko)	1999-11-25
HUP9901966A2 (hu)	1999-09-28
HU228567B1 (en)	2013-04-29
CN1314355A (zh)	2001-09-26
DE69717970D1 (de)	2003-01-30
WO1997029102A1 (en)	1997-08-14
HUP9901966A3 (en)	2002-01-28
EP0882725B1 (de)	2002-12-18
CN1100053C (zh)	2003-01-29
US6025370A (en)	2000-02-15
AU711914B2 (en)	1999-10-21
PT882725E (pt)	2003-04-30
HK1039118B (zh)	2009-01-30
DK0882725T3 (da)	2003-01-13
CA2242242C (en)	2001-08-07
HK1039118A1 (zh)	2002-04-12

Legal Events

Date

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2003-06-15

UEP

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