DK0885208T3 - Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser - Google Patents

Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser

Info

Publication number
DK0885208T3
DK0885208T3 DK97908304T DK97908304T DK0885208T3 DK 0885208 T3 DK0885208 T3 DK 0885208T3 DK 97908304 T DK97908304 T DK 97908304T DK 97908304 T DK97908304 T DK 97908304T DK 0885208 T3 DK0885208 T3 DK 0885208T3
Authority
DK
Denmark
Prior art keywords
compounds
taxoids
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
DK97908304T
Other languages
English (en)
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0885208T3 publication Critical patent/DK0885208T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97908304T 1996-03-06 1997-03-05 Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser DK0885208T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602804A FR2745814B1 (fr) 1996-03-06 1996-03-06 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1997/000386 WO1997032869A1 (fr) 1996-03-06 1997-03-05 Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK0885208T3 true DK0885208T3 (da) 2001-10-15

Family

ID=9489910

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97908304T DK0885208T3 (da) 1996-03-06 1997-03-05 Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser

Country Status (34)

Country Link
US (1) US6160135A (da)
EP (1) EP0885208B1 (da)
JP (1) JP2000506158A (da)
KR (1) KR19990087398A (da)
CN (1) CN1210525A (da)
AP (1) AP1023A (da)
AT (1) ATE204266T1 (da)
AU (1) AU715228B2 (da)
BG (1) BG63693B1 (da)
BR (1) BR9707887A (da)
CA (1) CA2248195A1 (da)
CZ (1) CZ283498A3 (da)
DE (1) DE69706146T2 (da)
DK (1) DK0885208T3 (da)
EA (1) EA001516B1 (da)
EE (1) EE03611B1 (da)
ES (1) ES2161446T3 (da)
FR (1) FR2745814B1 (da)
GE (1) GEP20012517B (da)
GR (1) GR3036410T3 (da)
HU (1) HUP9902425A3 (da)
IL (1) IL125998A (da)
IS (1) IS4809A (da)
NO (1) NO983472D0 (da)
NZ (1) NZ331040A (da)
OA (1) OA10855A (da)
PL (1) PL328691A1 (da)
PT (1) PT885208E (da)
SK (1) SK121598A3 (da)
TR (1) TR199801732T2 (da)
TW (1) TW474928B (da)
WO (1) WO1997032869A1 (da)
YU (1) YU38398A (da)
ZA (1) ZA971746B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
MA23823A1 (fr) 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
EP1044971A4 (en) * 1997-12-19 2001-11-07 Yakult Honsha Kk TAXAN DERIVATIVES
EP1020188A1 (en) * 1999-01-13 2000-07-19 Aventis Pharma S.A. New use of taxoid derivatives
CO5280224A1 (es) * 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
PL350028A1 (en) * 2000-02-02 2002-10-21 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents
JP2004525860A (ja) 2000-09-22 2004-08-26 ブリストル−マイヤーズ スクイブ カンパニー 併用化学療法剤の毒性を低下させる方法
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
CN1960721A (zh) 2004-03-05 2007-05-09 佛罗里达州立大学研究基金有限公司 C7乳酰氧基取代的紫杉烷类
CN101835769A (zh) * 2007-08-22 2010-09-15 6570763加拿大有限公司 将9-二氢-13-乙酰基浆果赤霉素ⅲ转化为多烯紫杉醇或太平洋紫杉醇的方法
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
AU2010310986A1 (en) 2009-10-29 2012-06-14 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
CN104650012A (zh) 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
KR930702323A (ko) * 1991-07-17 1993-09-08 하지메 나까가와 항종양 활성을 가진 화합물(nsc-lsc1) 및 그의 제조방법
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
DK1227093T3 (da) * 1993-03-22 2005-08-29 Univ Florida State Beta-lactamer, der kan anvendes til fremstilling af taxaner med en furyl- eller thienylsubstitueret sidekæde
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
AU684218B2 (en) * 1994-07-26 1997-12-04 Indena S.P.A. Semi-synthetic taxanes with anti-tumoural activity
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
ATE204266T1 (de) 2001-09-15
AP1023A (en) 2001-11-16
NO983472L (no) 1998-07-28
IS4809A (is) 1998-07-24
EE9800264A (et) 1999-02-15
GR3036410T3 (en) 2001-11-30
CN1210525A (zh) 1999-03-10
DE69706146D1 (de) 2001-09-20
CZ283498A3 (cs) 1999-01-13
EA001516B1 (ru) 2001-04-23
YU38398A (sh) 1999-07-28
DE69706146T2 (de) 2002-05-02
FR2745814A1 (fr) 1997-09-12
US6160135A (en) 2000-12-12
OA10855A (fr) 2003-02-05
BG102753A (en) 1999-09-30
KR19990087398A (ko) 1999-12-27
EP0885208A1 (fr) 1998-12-23
NZ331040A (en) 2000-02-28
EP0885208B1 (fr) 2001-08-16
SK121598A3 (en) 1999-01-11
AU715228B2 (en) 2000-01-20
IL125998A0 (en) 1999-04-11
HUP9902425A3 (en) 2001-08-28
NO983472D0 (no) 1998-07-28
AP9801335A0 (en) 1998-09-30
JP2000506158A (ja) 2000-05-23
FR2745814B1 (fr) 1998-04-03
HUP9902425A2 (hu) 2001-04-28
TR199801732T2 (xx) 1998-12-21
PT885208E (pt) 2001-11-30
EA199800795A1 (ru) 1999-02-25
PL328691A1 (en) 1999-02-15
IL125998A (en) 2002-02-10
EE03611B1 (et) 2002-02-15
ES2161446T3 (es) 2001-12-01
GEP20012517B (en) 2001-08-27
WO1997032869A1 (fr) 1997-09-12
ZA971746B (en) 1997-09-16
BR9707887A (pt) 1999-09-21
TW474928B (en) 2002-02-01
BG63693B1 (bg) 2002-09-30
AU2030297A (en) 1997-09-22
CA2248195A1 (fr) 1997-09-12

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