EE03611B1 - Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents

Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number
EE03611B1
EE03611B1 EE9800264A EE9800264A EE03611B1 EE 03611 B1 EE03611 B1 EE 03611B1 EE 9800264 A EE9800264 A EE 9800264A EE 9800264 A EE9800264 A EE 9800264A EE 03611 B1 EE03611 B1 EE 03611B1
Authority
EE
Estonia
Prior art keywords
taxoids
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
EE9800264A
Other languages
English (en)
Other versions
EE9800264A (et
Inventor
Bouchard Herv
Bourzat Jean-Dominique
Commer�on Alain
Original Assignee
Rh�Ne-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rh�Ne-Poulenc Rorer S.A. filed Critical Rh�Ne-Poulenc Rorer S.A.
Publication of EE9800264A publication Critical patent/EE9800264A/et
Publication of EE03611B1 publication Critical patent/EE03611B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
EE9800264A 1996-03-06 1997-03-05 Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid EE03611B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602804A FR2745814B1 (fr) 1996-03-06 1996-03-06 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1997/000386 WO1997032869A1 (fr) 1996-03-06 1997-03-05 Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EE9800264A EE9800264A (et) 1999-02-15
EE03611B1 true EE03611B1 (et) 2002-02-15

Family

ID=9489910

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800264A EE03611B1 (et) 1996-03-06 1997-03-05 Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (34)

Country Link
US (1) US6160135A (et)
EP (1) EP0885208B1 (et)
JP (1) JP2000506158A (et)
KR (1) KR19990087398A (et)
CN (1) CN1210525A (et)
AP (1) AP1023A (et)
AT (1) ATE204266T1 (et)
AU (1) AU715228B2 (et)
BG (1) BG63693B1 (et)
BR (1) BR9707887A (et)
CA (1) CA2248195A1 (et)
CZ (1) CZ283498A3 (et)
DE (1) DE69706146T2 (et)
DK (1) DK0885208T3 (et)
EA (1) EA001516B1 (et)
EE (1) EE03611B1 (et)
ES (1) ES2161446T3 (et)
FR (1) FR2745814B1 (et)
GE (1) GEP20012517B (et)
GR (1) GR3036410T3 (et)
HU (1) HUP9902425A3 (et)
IL (1) IL125998A (et)
IS (1) IS4809A (et)
NO (1) NO983472L (et)
NZ (1) NZ331040A (et)
OA (1) OA10855A (et)
PL (1) PL328691A1 (et)
PT (1) PT885208E (et)
SK (1) SK121598A3 (et)
TR (1) TR199801732T2 (et)
TW (1) TW474928B (et)
WO (1) WO1997032869A1 (et)
YU (1) YU38398A (et)
ZA (1) ZA971746B (et)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
MA23823A1 (fr) 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
KR100551945B1 (ko) * 1997-12-19 2006-02-20 가부시키가이샤 야쿠루트 혼샤 택산 유도체
EP1020188A1 (en) * 1999-01-13 2000-07-19 Aventis Pharma S.A. New use of taxoid derivatives
CO5280224A1 (es) * 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
SK13632001A3 (sk) * 2000-02-02 2002-06-04 Florida State University Research Foundation, Inc. C10 karbonátom substituované taxány ako protinádorové činidlá
MXPA03002494A (es) 2000-09-22 2004-05-24 Bristol Myers Squibb Co Metodo para reducir toxicidad de quimio terapias combinadas.
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
PA8625301A1 (es) 2004-03-05 2006-06-02 Univ Florida State Res Found Taxanos con sustituyente lactiloxilo en el c7
US20110118473A1 (en) * 2007-08-22 2011-05-19 6570763 Canada Inc. Process for converting 9-dihydro-13acetylbaccatin iii paclitaxel and docetaxel
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
EP2493466B1 (en) 2009-10-29 2021-03-10 Sanofi Mature IP Novel antitumoral use of cabazitaxel
CN104650012A (zh) * 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
KR930702323A (ko) * 1991-07-17 1993-09-08 하지메 나까가와 항종양 활성을 가진 화합물(nsc-lsc1) 및 그의 제조방법
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
DK0690867T3 (da) * 1993-03-22 2003-06-10 Univ Florida State Taxaner med furyl- eller thienylsubstitueret sidekæde
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
HU222496B1 (hu) * 1994-07-26 2003-07-28 Indena S.P.A. Félszintetikus taxánszármazékok, eljárás ezek előállítására, valamint ezeket tartalmazó gyógyászati készítmények
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
EE9800264A (et) 1999-02-15
WO1997032869A1 (fr) 1997-09-12
IS4809A (is) 1998-07-24
EA199800795A1 (ru) 1999-02-25
HUP9902425A2 (hu) 2001-04-28
BG102753A (en) 1999-09-30
EP0885208A1 (fr) 1998-12-23
AU715228B2 (en) 2000-01-20
PL328691A1 (en) 1999-02-15
HUP9902425A3 (en) 2001-08-28
BG63693B1 (bg) 2002-09-30
KR19990087398A (ko) 1999-12-27
GEP20012517B (en) 2001-08-27
NZ331040A (en) 2000-02-28
FR2745814A1 (fr) 1997-09-12
BR9707887A (pt) 1999-09-21
TW474928B (en) 2002-02-01
OA10855A (fr) 2003-02-05
ES2161446T3 (es) 2001-12-01
AP9801335A0 (en) 1998-09-30
IL125998A (en) 2002-02-10
PT885208E (pt) 2001-11-30
EP0885208B1 (fr) 2001-08-16
CA2248195A1 (fr) 1997-09-12
ZA971746B (en) 1997-09-16
DK0885208T3 (da) 2001-10-15
NO983472D0 (no) 1998-07-28
EA001516B1 (ru) 2001-04-23
TR199801732T2 (xx) 1998-12-21
NO983472L (no) 1998-07-28
YU38398A (sh) 1999-07-28
ATE204266T1 (de) 2001-09-15
IL125998A0 (en) 1999-04-11
GR3036410T3 (en) 2001-11-30
JP2000506158A (ja) 2000-05-23
US6160135A (en) 2000-12-12
DE69706146D1 (de) 2001-09-20
DE69706146T2 (de) 2002-05-02
CZ283498A3 (cs) 1999-01-13
FR2745814B1 (fr) 1998-04-03
SK121598A3 (en) 1999-01-11
AP1023A (en) 2001-11-16
AU2030297A (en) 1997-09-22
CN1210525A (zh) 1999-03-10

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Legal Events

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Effective date: 20020305