DK0895592T3 - Biosensoranordning og fremgangsmåde - Google Patents
Biosensoranordning og fremgangsmådeInfo
- Publication number
- DK0895592T3 DK0895592T3 DK97917194T DK97917194T DK0895592T3 DK 0895592 T3 DK0895592 T3 DK 0895592T3 DK 97917194 T DK97917194 T DK 97917194T DK 97917194 T DK97917194 T DK 97917194T DK 0895592 T3 DK0895592 T3 DK 0895592T3
- Authority
- DK
- Denmark
- Prior art keywords
- ligand
- peptide
- binding
- biosensor
- bound
- Prior art date
Links
- 239000003446 ligand Substances 0.000 abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000011230 binding agent Substances 0.000 abstract 2
- 239000000833 heterodimer Substances 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/002—Electrode membranes
- C12Q1/003—Functionalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/908—Gravimetric analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Electrotherapy Devices (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1638596P | 1996-04-25 | 1996-04-25 | |
| US1619696P | 1996-04-25 | 1996-04-25 | |
| PCT/CA1997/000275 WO1997041424A1 (fr) | 1996-04-25 | 1997-04-25 | Biocapteur et methode afferente |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0895592T3 true DK0895592T3 (da) | 2003-06-23 |
Family
ID=26688293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97917194T DK0895592T3 (da) | 1996-04-25 | 1997-04-25 | Biosensoranordning og fremgangsmåde |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6165335A (fr) |
| EP (1) | EP0895592B1 (fr) |
| JP (1) | JP2001503849A (fr) |
| AT (1) | ATE234461T1 (fr) |
| AU (1) | AU711956B2 (fr) |
| DE (1) | DE69719742T2 (fr) |
| DK (1) | DK0895592T3 (fr) |
| ES (1) | ES2194193T3 (fr) |
| IL (1) | IL126582A (fr) |
| MX (1) | MXPA98008826A (fr) |
| PT (1) | PT895592E (fr) |
| WO (1) | WO1997041424A1 (fr) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0855913A (ja) * | 1994-06-07 | 1996-02-27 | Texas Instr Inc <Ti> | サブミクロン相互接続の選択的空隙充填方法 |
| US6165335A (en) | 1996-04-25 | 2000-12-26 | Pence And Mcgill University | Biosensor device and method |
| US7105307B2 (en) | 1997-08-30 | 2006-09-12 | Cyclacel, Ltd. | Compositions and methods for screening for modulators of enzymatic activity |
| GB9718358D0 (en) * | 1997-08-30 | 1997-11-05 | Univ Leeds | Chemical modification |
| EP0962759B1 (fr) * | 1998-06-02 | 2003-08-20 | International Business Machines Corporation | Méthode et dispositif pour l'identification d'une substance utilisant des interactions de surfaces |
| US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
| US6897073B2 (en) | 1998-07-14 | 2005-05-24 | Zyomyx, Inc. | Non-specific binding resistant protein arrays and methods for making the same |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6682942B1 (en) | 1998-07-14 | 2004-01-27 | Zyomyx, Inc. | Microdevices for screening biomolecules |
| NL1009871C2 (nl) * | 1998-08-14 | 2000-02-15 | Holland Biomaterials Group B V | Inrichting voor het onderzoeken van chemische interacties en werkwijze die gebruik maakt van een dergelijke inrichting. |
| AU2898500A (en) | 1999-03-02 | 2000-09-21 | Helix Biopharma Corporation | Biosensor device and method |
| US6300141B1 (en) * | 1999-03-02 | 2001-10-09 | Helix Biopharma Corporation | Card-based biosensor device |
| US7312087B2 (en) * | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US7435579B2 (en) * | 2000-04-17 | 2008-10-14 | Purdue Research Foundation | Biosensor and related method |
| US7306924B2 (en) * | 2000-04-17 | 2007-12-11 | Purdue Research Foundation | Biosensor and related method |
| WO2001079529A1 (fr) | 2000-04-17 | 2001-10-25 | Purdue Research Foundation | Biocapteur et procede associe |
| CA2314398A1 (fr) * | 2000-08-10 | 2002-02-10 | Edward Shipwash | Jeux ordonnes de microechantillons et microsystemes pour l'analyse d'acides amines et le sequencage de proteines |
| AU2001287451A1 (en) * | 2000-09-01 | 2002-03-13 | Helix Biopharma Corporation | Biosensor assay device and method |
| WO2002063280A1 (fr) * | 2001-02-06 | 2002-08-15 | Auburn University | Dispositifs de detection de ligands et utilisation de ces dispositifs |
| EP1390732A4 (fr) * | 2001-04-03 | 2006-09-27 | Combimatrix Corp | Electrode superieure pour microreseaux electrochimiques |
| ATE380342T1 (de) * | 2001-05-07 | 2007-12-15 | Hipep Lab | Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben |
| US20030143576A1 (en) * | 2001-08-22 | 2003-07-31 | Heman Chao | Method and device for integrated protein expression, purification and detection |
| DE10141691A1 (de) * | 2001-08-25 | 2003-03-13 | Friz Biochem Gmbh | Verdrängungsassay zur Detektion von Ligat-Ligand-Assoziationsereignissen |
| US6778316B2 (en) * | 2001-10-24 | 2004-08-17 | William Marsh Rice University | Nanoparticle-based all-optical sensors |
| AU2003208811A1 (en) * | 2002-02-05 | 2003-09-02 | Immunolex Therapeutics Aps | A pair of antibody fv fragments stabilized by coiledcoil peptides |
| US20040014946A1 (en) * | 2002-04-25 | 2004-01-22 | Heman Chao | Protein interaction method and composition |
| US20040072208A1 (en) * | 2002-05-23 | 2004-04-15 | Peter Warthoe | Surface acoustic wave sensors and method for detecting target analytes |
| US6903023B2 (en) * | 2002-09-16 | 2005-06-07 | International Business Machines Corporation | In-situ plasma etch for TERA hard mask materials |
| US7015471B2 (en) * | 2002-09-25 | 2006-03-21 | North Carolina State University | Surface plasmon resonance systems and methods having a variable charge density layer |
| US7430039B2 (en) * | 2002-10-11 | 2008-09-30 | Canon Kabushiki Kaisha | Sensor |
| US20040258832A1 (en) * | 2003-06-17 | 2004-12-23 | Barklund Anna M. | Method of chemical analysis using microwells patterned from self-assembled monolayers and substrates |
| AT501110A1 (de) * | 2003-09-16 | 2006-06-15 | Upper Austrian Res Gmbh | Arrays zur bindung von molekülen |
| US9645091B2 (en) * | 2004-01-28 | 2017-05-09 | Bamburgh Marrsh, Llc | Specimen sample collection device and test system |
| US7786261B2 (en) | 2004-09-02 | 2010-08-31 | National Research Council Of Canada | Coiled-coil fusion proteins comprising cell receptor domains |
| JP2006153831A (ja) * | 2004-10-27 | 2006-06-15 | Mitsubishi Chemicals Corp | カンチレバーセンサ、センサシステム及び検体液中の検出対象物質の検出方法 |
| US7892414B1 (en) * | 2004-11-19 | 2011-02-22 | The United States Of America As Represented By The Secretary Of Army | Electrochemical biosensors, applications and methods of making biosensors |
| US7745143B2 (en) * | 2004-11-19 | 2010-06-29 | Plexera, Llc | Plasmon resonance biosensor and method |
| US20090262356A1 (en) * | 2008-03-27 | 2009-10-22 | Plexera, Llc | User interface and method for using an spr system |
| US7889347B2 (en) | 2005-11-21 | 2011-02-15 | Plexera Llc | Surface plasmon resonance spectrometer with an actuator driven angle scanning mechanism |
| US7463358B2 (en) | 2005-12-06 | 2008-12-09 | Lumera Corporation | Highly stable surface plasmon resonance plates, microarrays, and methods |
| GB2433505A (en) * | 2005-12-20 | 2007-06-27 | Sharp Kk | Capture agents for binding a ligand |
| GB2433506A (en) * | 2005-12-20 | 2007-06-27 | Sharp Kk | A method of producing a multimeric capture agent |
| GB2433591A (en) * | 2005-12-20 | 2007-06-27 | Sharp Kk | Method for functionalising a hydrophobic substrate |
| WO2009005542A2 (fr) * | 2007-02-09 | 2009-01-08 | Stc.Unm | Détection d'agents biologiques à l'aide d'un capteur biologique à ondes acoustiques de surface à cisaillement horizontal |
| US8263377B2 (en) | 2007-04-03 | 2012-09-11 | Plexera, Llc | Label free kinase assays and reagents |
| GB0711994D0 (en) | 2007-06-21 | 2007-08-01 | Foundation For Res And Technol | Molecular Conformation Biosensing |
| US7695976B2 (en) * | 2007-08-29 | 2010-04-13 | Plexera Bioscience, Llc | Method for uniform analyte fluid delivery to microarrays |
| US8004669B1 (en) | 2007-12-18 | 2011-08-23 | Plexera Llc | SPR apparatus with a high performance fluid delivery system |
| KR101644165B1 (ko) * | 2009-09-25 | 2016-07-29 | 삼성전자주식회사 | 표면탄성파 디바이스 및 바이오센서 |
| EP2630479B1 (fr) | 2010-10-20 | 2020-04-08 | Qorvo US, Inc. | Appareil et procédé de mesure de cinétiques de liaison et de concentration avec un capteur résonant |
| EP2934901A4 (fr) | 2012-12-20 | 2016-07-20 | Hewlett Packard Development Co | Support d'impression comprenant une couche de traitement |
| TWI504891B (zh) * | 2014-05-08 | 2015-10-21 | 中原大學 | 尿酸偵測電極與其製法 |
| JP7280590B2 (ja) * | 2016-01-28 | 2023-05-24 | ロズウェル バイオテクノロジーズ,インコーポレイテッド | 大スケールの分子電子工学センサアレイを使用する被分析物を測定するための方法および装置 |
| GB201714478D0 (en) | 2017-09-08 | 2017-10-25 | Univ Bristol | Sensor |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3891507A (en) | 1974-05-30 | 1975-06-24 | American Cyanamid Co | Organ function test cards |
| US4038030A (en) | 1975-04-10 | 1977-07-26 | American Hospital Supply Corporation | Profile analysis pack and method |
| US3990850A (en) | 1976-01-06 | 1976-11-09 | Akzona Incorporated | Diagnostic test card |
| GB8417301D0 (en) | 1984-07-06 | 1984-08-08 | Serono Diagnostics Ltd | Assay |
| EP0215669A3 (fr) | 1985-09-17 | 1989-08-30 | Seiko Instruments Inc. | Diagnostique et procédé d'analyse de composés biochimiques, microbes et cellules |
| US5192507A (en) | 1987-06-05 | 1993-03-09 | Arthur D. Little, Inc. | Receptor-based biosensors |
| CA1335879C (fr) | 1987-07-27 | 1995-06-13 | Bruce Andrew Cornell | Membranes dotees de recepteurs |
| DE3870156D1 (de) | 1987-10-13 | 1992-05-21 | Taiyo Yuden Kk | Chemische sensoren und deren bestandteile. |
| SE8804074D0 (sv) | 1988-11-10 | 1988-11-10 | Pharmacia Ab | Sensorenhet och dess anvaendning i biosensorsystem |
| SE462408B (sv) | 1988-11-10 | 1990-06-18 | Pharmacia Ab | Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5200051A (en) | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5212050A (en) * | 1988-11-14 | 1993-05-18 | Mier Randall M | Method of forming a permselective layer |
| US5089112A (en) | 1989-03-20 | 1992-02-18 | Associated Universities, Inc. | Electrochemical biosensor based on immobilized enzymes and redox polymers |
| DK0418355T3 (da) | 1989-04-04 | 1994-09-12 | Urban Gerald | Fremgangsmåde til immobilisering af proteiner, peptider, coenzymer, etc. på et substrat |
| US5116481A (en) | 1989-04-07 | 1992-05-26 | Hitachi, Ltd. | Anion-selective, sensitive film, electrode containing the same and the use thereof |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5268305A (en) | 1989-06-15 | 1993-12-07 | Biocircuits Corporation | Multi-optical detection system |
| US5491097A (en) | 1989-06-15 | 1996-02-13 | Biocircuits Corporation | Analyte detection with multilayered bioelectronic conductivity sensors |
| US5368712A (en) * | 1989-11-02 | 1994-11-29 | Synporin Technologies, Inc. | Biologically mimetic synthetic ion channel transducers |
| US5288636A (en) | 1989-12-15 | 1994-02-22 | Boehringer Mannheim Corporation | Enzyme electrode system |
| IL93020A (en) * | 1990-01-09 | 1995-06-29 | Yeda Res & Dev | Biosensors comprising a lipid bilayer doped with ion channels anchored to a recording electrode by bridging molecules |
| US5104619A (en) | 1990-01-24 | 1992-04-14 | Gds Technology, Inc. | Disposable diagnostic system |
| US5478756A (en) | 1990-07-24 | 1995-12-26 | Fisons Plc | Chemical sensor for detecting binding reactions |
| DK0639269T3 (da) | 1991-03-27 | 2002-10-07 | Ambri Ltd | Ionreservoir ved elektrodeoverflade |
| WO1993015110A1 (fr) * | 1992-01-31 | 1993-08-05 | Whitehead Institute For Biomedical Research | Sequences d'acides amines s'appariant de maniere specifique |
| WO1993021528A1 (fr) | 1992-04-22 | 1993-10-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | Capteurs a membranes lipidiques |
| US5736410A (en) | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| JPH08505123A (ja) | 1992-10-01 | 1996-06-04 | オーストラリアン メンブレイン アンド バイオテクノロジィ リサーチ インスティチュート | 改良されたセンサー膜 |
| EP0722563A4 (fr) | 1993-08-24 | 1998-03-04 | Metrika Lab Inc | Nouveau dispositif electronique d'analyse jetable |
| US5527711A (en) | 1993-12-13 | 1996-06-18 | Hewlett Packard Company | Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques |
| IL108726A (en) | 1994-02-22 | 1999-12-31 | Yissum Res Dev Co | Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor |
| FR2720832A1 (fr) | 1994-04-22 | 1995-12-08 | Francis Garnier | Electrodes et membranes électroactives à base de peptides bioactifs, pour la reconnaissance, l'extraction ou le relargage d'espèces biologiquement actives. |
| US5824483A (en) | 1994-05-18 | 1998-10-20 | Pence Inc. | Conformationally-restricted combinatiorial library composition and method |
| ATE196297T1 (de) * | 1994-05-18 | 2000-09-15 | Synthetic Peptides Inc | Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung |
| US5514501A (en) | 1994-06-07 | 1996-05-07 | The United States Of America As Represented By The Secretary Of Commerce | Process for UV-photopatterning of thiolate monolayers self-assembled on gold, silver and other substrates |
| EP0690306A1 (fr) | 1994-06-28 | 1996-01-03 | Mochida Pharmaceutical Co., Ltd. | Méthode et dispositif à utiliser dans les essais de liaisons spécifiques |
| WO1996002830A1 (fr) | 1994-07-14 | 1996-02-01 | Technobiochip | Biocapteur, et procede et instrument permettant de deposer des couches monomoleculaires alternees |
| US5485277A (en) | 1994-07-26 | 1996-01-16 | Physical Optics Corporation | Surface plasmon resonance sensor and methods for the utilization thereof |
| DE4430023A1 (de) | 1994-08-24 | 1996-02-29 | Boehringer Mannheim Gmbh | Elektrochemischer Sensor |
| US5624537A (en) | 1994-09-20 | 1997-04-29 | The University Of British Columbia - University-Industry Liaison Office | Biosensor and interface membrane |
| DE4433980C2 (de) | 1994-09-23 | 1996-08-22 | Boehringer Ingelheim Int | Verfahren und Biosensorhit zur Untersuchung der Wechselwirkung von Biomolekülen mittels Oberflächen-Plasma-Resonanz |
| SE9403245D0 (sv) | 1994-09-26 | 1994-09-26 | Pharmacia Biosensor Ab | Improvements relating to bilayer lipid membranes |
| US5567301A (en) | 1995-03-01 | 1996-10-22 | Illinois Institute Of Technology | Antibody covalently bound film immunobiosensor |
| US5798030A (en) | 1995-05-17 | 1998-08-25 | Australian Membrane And Biotechnology Research Institute | Biosensor membranes |
| AUPN366995A0 (en) | 1995-06-20 | 1995-07-13 | Australian Membrane And Biotechnology Research Institute | Self-assembly of bilayer membrane sensors |
| IT1275482B (it) | 1995-07-05 | 1997-08-07 | Cooperativa Centro Ricerche Po | Biosensori elettrochimici basati su trasduttori compositi |
| FR2737825B1 (fr) | 1995-08-11 | 1997-09-12 | Sextant Avionique | Procede d'exploitation du signal de sortie d'un capteur ou d'un convertisseur recevant une energie impulsionnelle intermittente, et dispositif de mise en oeuvre |
| US6165335A (en) * | 1996-04-25 | 2000-12-26 | Pence And Mcgill University | Biosensor device and method |
| US5955379A (en) | 1996-04-25 | 1999-09-21 | Mcgill University | Biosensor device and method |
| WO1997041425A1 (fr) | 1996-04-25 | 1997-11-06 | Pence, Inc. | Biocapteur et methode afferente |
| US5707502A (en) | 1996-07-12 | 1998-01-13 | Chiron Diagnostics Corporation | Sensors for measuring analyte concentrations and methods of making same |
| US6074616A (en) | 1998-01-05 | 2000-06-13 | Biosite Diagnostics, Inc. | Media carrier for an assay device |
-
1997
- 1997-04-24 US US08/845,660 patent/US6165335A/en not_active Expired - Fee Related
- 1997-04-25 DK DK97917194T patent/DK0895592T3/da active
- 1997-04-25 ES ES97917194T patent/ES2194193T3/es not_active Expired - Lifetime
- 1997-04-25 AT AT97917194T patent/ATE234461T1/de not_active IP Right Cessation
- 1997-04-25 PT PT97917194T patent/PT895592E/pt unknown
- 1997-04-25 IL IL12658297A patent/IL126582A/en not_active IP Right Cessation
- 1997-04-25 WO PCT/CA1997/000275 patent/WO1997041424A1/fr not_active Ceased
- 1997-04-25 DE DE69719742T patent/DE69719742T2/de not_active Expired - Fee Related
- 1997-04-25 EP EP97917194A patent/EP0895592B1/fr not_active Expired - Lifetime
- 1997-04-25 JP JP53842197A patent/JP2001503849A/ja active Pending
- 1997-04-25 AU AU25638/97A patent/AU711956B2/en not_active Ceased
- 1997-04-25 MX MXPA98008826A patent/MXPA98008826A/es unknown
-
2000
- 2000-05-24 US US09/578,353 patent/US6478939B1/en not_active Expired - Fee Related
- 2000-07-27 US US09/626,775 patent/US6461490B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2563897A (en) | 1997-11-19 |
| US6461490B1 (en) | 2002-10-08 |
| PT895592E (pt) | 2003-07-31 |
| EP0895592A1 (fr) | 1999-02-10 |
| EP0895592B1 (fr) | 2003-03-12 |
| MXPA98008826A (es) | 2002-06-11 |
| ES2194193T3 (es) | 2003-11-16 |
| WO1997041424A1 (fr) | 1997-11-06 |
| AU711956B2 (en) | 1999-10-28 |
| DE69719742D1 (de) | 2003-04-17 |
| IL126582A0 (en) | 1999-08-17 |
| US6165335A (en) | 2000-12-26 |
| IL126582A (en) | 2004-03-28 |
| JP2001503849A (ja) | 2001-03-21 |
| DE69719742T2 (de) | 2004-03-18 |
| US6478939B1 (en) | 2002-11-12 |
| ATE234461T1 (de) | 2003-03-15 |
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